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6th December 2018
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Organic chemistry

G Richard Stephenson, 06/12/2018

Combining two achiral natural product (NP) fragments together, as in (3), can introduce chirality. In this case, the chromane (1) and tetrahydropyrimidinone (2) sections are each commonly found in larger structures that have a wide selection of types of bioactivity: antitumour, antibacterial, and central nervous system bioactivity in the case of chromanes, and antibiotic, carotinoid biosynthesis inhibition and antiproliferative effects for tetrahydropyrimidinones.

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Our quantum world

Dennis Rouvray, 06/12/2018

Because of its exceptionally wide applicability, quantum mechanics can now arguably be claimed to occupy pride of place in the current pantheon of physical theories.

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Staying healthy

John Mann, 06/12/2018

The study of immunology began with the experiments of Edward Jenner in 1796. His observation that milkmaids who had been exposed to cowpox never contracted smallpox encouraged him to experiment with inoculation with pus from cowpox pustules.

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