Read the organic chemistry highlights from C&I Issue 6 2022 written by G. Richard Stephenson, University of East Anglia, UK on building pyrrole rings to create axial chirality, spirocycles from an enantioselective Diels−Alder reaction and perylenes with a diagonal distortion of electron density.
Read the Biomedical highlight by Kevin Burgess, Texas A&M University, US in C&I Issue 6 2022 on bettering Nature’s PD-1: Meta-mimicry, application of multicomponent reactions in fragment compilation: Small molecules PD-1 mimics and Applications of PD-1•PD-L1 therapy.