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Telephone: +44 (0)1638 781709

Going waterless

CondenSyn waterless condenser from AsyntThe CondenSyn waterless condenser from Asynt has been adopted by the Technicians Sustainability Working Group (TSWG) operating within the Biomolecular Science and Medicinal Chemistry Division at Nottingham University (UK).

Lee Hibbett, a founder member of the TSWG, said: ‘Water condensers have been used in our scientific labs for decades for refluxing reactions. With a typical reflux reaction running for 16 hours we calculated a single water condenser uses 20-litres of water/hour equating to a waste of 320L/reaction. Scaling this by our 37 scientists doing two reactions/week, this equates to a saving of 1,231,360L/year by adopting the CondenSyn waterless condensers.’

The CondenSyn is very easy to clean and maintain. An anti-roll feature helps prevent it rolling off laboratory surfaces. A typical laboratory, replacing standard water condensers with CondenSyn air cooled condensers, can expect to see a return on its investment in as little as six months.

For further information about the Biomolecular Science and Medicinal Chemistry Division at Nottingham University, visit:


Telephone: +81-466 238382

Comparison of seals and silicone mats

BioChromato Rapid Slit SealsBioChromato reports the pharmacokinetics department at a leading Japanese pharmaceutical company has found RAPID Slit Seals offer significant benefits, compared with conventional silicone mats, for maintaining the integrity of microplate samples. A self-closing microplate seal, it returns to its original state even when punched with an HPLC or LC/MS autosampler.

Traditionally, the department used silicone mats to maintain the integrity of 96-well microplates. While this approach worked well, it was expensive and the seals had to be carefully washed before reuse as contamination was a concern. Switching to disposible seals has eliminated contamination and significantly reduced the cost/analysis.

In addition, the autosampler injection hole in the disposible plate seals rapidly closes after each injection, making it ideal for samples that might be selected for further analysis. Even when stored for several days in volatile solvents, such as acetonitrile, the seals were found to minimise solvent loss through evaporation ensuring sample integrity and the validity of repeat analyses.



Telephone: +44 (0)845 864 7747

The Cold Coil II Flow Reactor Module from UniqsisLow temperature flow chemistry

The Cold Coil II Flow Reactor Module from Uniqsis provides a flexible, entry-level solution for low temperature flow chemistry. An external thermoregulation circulator can maintain temperatures between -78°C and +150°C for extended periods. A glass cover eliminates convective effects within fume cupboards; a vacuum jacketed cover is available for very low temperatures.

It is compatible with all Uniqsis coil reactors, from 2.0ml to 60ml capacity. A clamping mechanism holds the reactor in place and ensures optimal thermal contact while allowing easy reactor interchange. It can be converted into a photoreactor with a Uniqsis PhotoSyn high power LED light unit. An optional Glass Static Mixer chip module allows it to be used as a rapid mixing device before flowing directly into a coil reactor as an incubator module.

It is compatible with the Uniqsis HotColumn multiple column reactor adaptor for packed bed applications. For remote measurement, an optional internal temperature probe can be connected.