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15th May 2018
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Asynt

Parallel synthesiser

Asynt reports on how a DrySyn OCTO 8-position parallel synthesiser has benefited early stage discovery chemistry at Cancer Research UK (Cambridge, UK). Designed to work with any hotplate stirrer, the Octo has enabled the CRUK Therapeutic Discovery Laboratories to increase the productivity of their small-scale synthetic reactions.

Dr Peter Blencowe, a senior scientist at the CRUK Therapeutic Discovery Laboratories, commented: ‘We have used the DrySyn OCTO to perform a variety of heterogeneous catalysis reactions under nitrogen to eliminate formation of side products. Parallel reactions are very easy to set up saving time on the degassing and space on the heating arrangement required. We all like the unit and it has particularly helped us improve workflow when tasked with doing arrays of heated reactions in early discovery chemistry.’

The compact synthesiser accommodates low cost consumable reaction tubes each with a working volume of 5-6 ml. The large surface area of these tubes enables the OCTO to be used for air cooled gentle reflux reactions.

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