2 April - 4 April 2014

31st SCI Process Development Symposium

Organised by:

SCI’s Fine Chemicals Group

Churchill College, Cambridge

Registration Closed

This event is no longer available for registration.

Synopsis

The symposium aims to bring together a wide range of speakers from across the Pharmaceutical, Agrochemical and Fine Chemical industries, as well as from an academic background.

The area of Process Development continues to be a challenging and important area for the research into and application of modern synthetic organic chemistry, as well as enabling technologies. Process Development is the application of chemistry to the scale up of new synthetic processes from the laboratory, through pilot plant to full scale commercial manufacture and into life cycle management. It is an extremely broad discipline, crossing the boundaries between synthetic organic chemistry, process technology and chemical engineering.

Attendees

This meeting brings together experts from across the entire spectrum of the discipline to present state of the art process development. As an established and well attended meeting, the process development symposium offers an excellent opportunity for networking between like-minded process scientists of all levels of experience and from all areas of the chemical industry.

Programme

Day 1 - Wednesday 2 April

11:00: Registration and refreshments
12:15: Lunch
13:25: Opening remarks
13:30: Evaluation of several routes to advanced pregabalin intermediates: Synthesis and enantioselective enzymatic reduction using ene-reductases
Dr Simon Davies, Pfizer, Ireland
14:10: Flow chemistry at the interface of research and development
Dr Glyn Hughes, Novartis Institutes for Biomedical Research, UK
14:50: Continuous processes - sustainable manufacturing
Dr Jörg Schrickel, CABB, Switzerland
15:30: Refreshment break
16:10: Process research and development of a challenging drug candidate
Dr Yi-Yin Ku, Abbvie, US
16:50: Cediranib crude: Understanding as a guide to the development of a simple alkylation
Dr Ian Ashworth, AstraZeneca, UK
17:30: Discussion and close
17:45: Drinks reception sponsored by AMRI Global
19:00: Dinner for residents

Day 2 - Thursday 3 April

09:00: Process research and development to enable large scale synthesis of merck drug candidates
Dr Edward Cleator, Merck Sharp and Dohme, UK
09:40: Implementing PAT for pharmaceutical processes
Dr Jacques Wiss, Novartis Pharma AG, Switzerland
10:20: Refreshment break
10:50: From hydrogenation to dehydrogenation - developing versatile catalysts for fine chemicals synthesis
Prof Jianliang Xiao, University of Liverpool, UK
11:30: Vilanterol trifenatate: chemistry, manufacturing and control
Dr Matt Popkin, GlaxoSmithKline, UK
12:10: Lunch
13:10: Use of continuous process for the production of pharmaceutical products in SK
Dr Junku Park, SK Biopharmaceuticals, Korea
13:50: Once through continuous slurry hydrogenations
Prof Frans Muller, University of Leeds, UK
14:30: Refreshment break
15:00: Towards a scalable synthesis of the desoxy-biphenomycin B core
Dr Joachim Krueger, Bayer Pharma AG, Global Drug Discovery - Chemical Development, Germany
15:40: Synthetic organic photochemistry: batch or flow?
Prof Kevin Booker–Milburn
16:40: Discussion and close
17:30: Drinks reception sponsored by Johnson Matthey
19:00: Symposium dinner

Day 3 - Friday 4 April

09:00: The biocatalysis toolbox - current successes and future victories
Dr Andy Wells, Chem 21/Charnwood Technical Consulting, UK
09:40: Application of advanced process control to the design and optimisation of crystallisation processes
Prof Brian Glennon, University College Dublin, Ireland
10:20: Refreshment break
10:50: Route and process design for a potent anti-inflammatory drug candidate - fun with catalysis!
Mr Alan Pettman, Pfizer Chemical Research and Development, UK
11:30: Utilising Vilsmeier and intramolecular Diels Alder reactions to derive an isoindolone API
Mr Michael Golden, AstraZeneca, UK
12:10: Close of meeting

Accessibility Grants

SCI accessibility grants are available to support SCI members with disabilities, long term health conditions, those who require a carer, and members who are nursing parents to attend SCI events. Download an application form to apply for a grant.

Venue and Contact

Churchill College

Churchill College is one of 31 Colleges that comprises the University of Cambridge. Founded in 1960, it is a 15 minute walk from the centre of Cambridge. Despite the concentration of hi-tech and science industries around Cambridge, the centre still retains the atmosphere of a small town, renowned for the many university colleges and places of interest. Further information about Cambridge and alternative accommodation can be found on the following website: www.visitcambridge.org. Please click here for a location map.

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org

Fees

Earlybird rates before 31 January 2014
GB£360 . . . . . . . . . . . . . . . .SCI Member
GB£390 . . . . . . . . . . . . . . . .Non-Member
GB£255 . . . . . . . . . . . . . . . .Subsidised Member

Standard rates after 31 January 2014
GB£485 . . . . . . . . . . . . . . . . SCI Member
GB£540 . . . . . . . . . . . . . . . . Non-Member
GB£280 . . . . . . . . . . . . . . . . Subsdised Member

Accommodation fees

GB£176. . . . . . . . Single Ensuite Room (with private bathroom)
GB£140.. . . . . . . .Single Standard Room (with shared bathroom)

To register for the symposium and to book accommodation at the college please call conferences on +44 (0) 20 7598 1561

Become an SCI Member and save on this and future events

See Membership Options

Booking Process/Deadlines

For booking terms and conditions click here.

CPD Info

SCI Members attending this meeting are able to claim CPD points.

Additional Info

Organising committee

Dr Louis Diorazio, AstraZeneca, UK
Dr Alan Ironmonger, GlaxoSmithKline, UK
Dr David Lathbury, AMRI Global, UK
Dr Lisa Mitchell, Syngenta, UK
Mr Robert Walton, Pfizer, UK

Exhibition

An exhibition will run alongside the conference during refreshment breaks, for companies and related organisations who may wish to exhibit. For further information and prices please email jacqui.maguire@soci.org.

Accommodation

Accommodation for delegates at the college comprises either single study ensuite or single study standard bedrooms. Rooms will be allocated on a first-come, first served basis.

The accommodation package is for 2 nights - Wednesday 2 and Thursday 4 April and includes Full English or Continental breakfast plus an evening meal on Wednesday 2 April. Rooms must be vacated by 10.00am on the day of departure. Luggage storage will be available.
Those not wishing to stay in college accommodation can book accommodation directly through www.visitcambridge.org

Please note: Bedrooms at the college will be available from 14.00 on the day of arrival.

Travel

Travel to Cambridge is convenient by road or rail. Churchill College is on Storey's Way, off the A1303 one mile west of the city centre and close to the M11 motorway. There are frequent train services to Cambridge from London King's Cross and Liverpool Street Stations. The nearest international airport is London Stansted (30 miles) which has rail and coach links to Cambridge. From London Heathrow and Gatwick Airports there are express rail links to central London for onward rail journeys as above. There are also coach links from both airports direct to Cambridge.