25 March - 27 March 2015

32nd SCI Process Development Symposium

Organised by:

SCI’s Fine Chemicals Group

Churchill College, Cambridge, UK

Registration Closed

This event is no longer available for registration.

Synopsis

The area of Process Development continues to be a challenging and important area for the research into and application of modern synthetic organic chemistry, as well as enabling technologies. Process Development is the application of chemistry to the scale up of new synthetic processes from the laboratory, through pilot plant to full scale commercial manufacture and into life cycle management. It is an extremely broad discipline, crossing the boundaries between synthetic organic chemistry, process technology and chemical engineering.

Attendees

The symposium aims to bring together a wide range of speakers and delegates from across the Pharmaceutical, Agrochemical and Fine Chemical industries, as well as from an academic background.

Programme

Day 1 - Wednesday 25 March

11:00: Registration and refreshments
12:15: Lunch
13:25: Opening remarks
13:30: Scale-up from the lab to the plant - have you got the correct safety data?
Dr Ian Priestley, Syngenta Ltd, UK
14:10: Chem21 - All made by biology? New opportunities and challenges for process chemistry
Dr Anton Glieder, Graz University of Technology, Austria
14:50: Control in process development - evolution of the manufacturing route to Vestipitant
Dr Richard Horan, GlaxoSmithKline, UK
15:30: Refreshment break and exhibition
16:10: Pd, Cr and Ag in C-H activation: reactivity and selectivity control in the synthesis of biaryls
Prof Igor Larrosa, University of Manchester, UK
16:50: Aspects of the chemistry of buprenorphine and related compounds
Dr John Carey, Indivior, UK
17:30: Closing remarks
17:45: Wine reception (sponsored by Johnston Matthey) and exhibition
19:00: Dinner for residents

Day 2 - Thursday 26 March

09:00: Sirturo™: the process development story
Dr Lucie Zimmer, Johnson & Johnson, Switzerland
09:40: The value and practice of NMR in process development
Dr Mike Bernstein, Mestrelab Research, UK
10:20: Refreshment break and exhibition
10:50: The value of recycling in early process design
Mr Andrew Robinson, Tradebe Solvent Recycling Ltd, UK
11:30: Reducing waste and adding value to by-products through novel processing technologies
Dr James Tunstall, The Biorenewables Development Centre, UK
12:10: Lunch and exhibition
13:10: Definition of starting materials for the synthesis of chemical active substances: the EMA view
Dr Robert Bream, European Medicines Agency, UK
13:50: New continuous flow process for the preparation of (chiral) amines
Prof John Blacker, University of Leeds, UK
14:30: Process models for design space exploration using continuous flow reactors
Mr Christopher Hone, Institute of Process Research and Development (iPRD), UK
15:10: Refreshment break and exhibition
15:40: Electrochemistry with on-line mass spectrometry - a technique with Potential for accelerating pharmaceutical R+D
Dr Mark Taylor, Pfizer Worldwide R+D, UK
16:20: Syngenta, AstraZeneca and Pfizer prize for process chemistry research 2014
Prof Steven Nolan, University of St Andrew's, UK
17:20: Closing remarks
17:30: Wine reception and exhibition
19:00: Conference dinner

Day 3 - Friday 27 March

09:00: Process development of biopharmaceuticals
Dr Paul Varley, Medimmune, UK
09:40: Overcoming electronics with strategy: development of an efficient synthesis of a novel antiretroviral
Dr David Conlon, Bristol-Myers Squibb, USA
10:20: Refreshment break and exhibition
10:50: A chemist's guide to impurities - how to navigate the impurity maze
Dr Andrew Teasdale, AstraZeneca, UK
11:30: Development of a commercial reductive amination
Dr Marie Kissane, Eli Lilly S.A., Ireland
12:10: Close

Venue and Contact

Churchill College

University of Cambridge
Storey's Way
Cambridge
CB3 0DS

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org

Fees

Earlybird fees - before 23 January 2015
GB£365 . . . . . . . . . .SCI Member
GB£255. . . . . . . . . . SCI Subsidised Member
GB£395 . . . . . . . . . .Non Member

Standard fees - after 23 January 2015
GB£490 . . ... . . . . . .SCI Member
GB£280. . . . . . . . . . SCI Subsidised Member
GB£545 . . . . . . . . . .Non Member

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Booking Process/Deadlines

For booking terms and conditions click here.

CPD Info

SCI Members attending this meeting are able to claim CPD points.

Additional Info

Exhibition

An exhibition will run alongside the conference during refreshment breaks, for companies and related organisations who may wish to exhibit. For further information and prices please email jacqui.maguire@soci.org.

Accommodation

Accommodation for delegates at the college comprises either single study ensuite or single study standard bedrooms. Rooms will be allocated on a first-come, first served basis.

The accommodation package is for 2 nights - Wednesday 25 and Thursday 26 March and includes Full English or Continental breakfast plus an evening meal on Wednesday 25 March. Rooms must be vacated by 10.00am on the day of departure. Luggage storage will be available.
Those not wishing to stay in college accommodation can book accommodation directly through www.visitcambridge.org

Travel

Travel to Cambridge is convenient by road or rail. Churchill College is on Storey's Way, off the A1303 one mile west of the city centre and close to the M11 motorway. There are frequent train services to Cambridge from London King's Cross and Liverpool Street Stations. The nearest international airport is London Stansted (30 miles) which has rail and coach links to Cambridge. From London Heathrow and Gatwick Airports there are express rail links to central London for onward rail journeys as above. There are also coach links from both airports direct to Cambridge.