11 April - 13 April 2018

35th SCI Process Development Symposium

Organised by:

SCI's Fine Chemicals Group

Cambridge

Registration Closed

This event is no longer available for registration.

Synopsis

Process Development is the application of chemistry to the scale up of new synthetic processes from the laboratory, through pilot plant to full scale commercial manufacture and into life cycle management. It is an extremely broad discipline, crossing the boundaries between synthetic organic chemistry, process technology and chemical engineering.

The area of Process Development continues to be a challenging and important area for the research into and application of modern synthetic organic chemistry, as well as enabling technologies.

Attendees
The symposium aims to bring together a wide range of speakers from across the Pharmaceutical, Agrochemical and Fine Chemical industries, as well as from an academic background. This meeting brings together experts from across the entire spectrum of the discipline to present state of the art process development. As an established and well attended meeting, the process development symposium offers an excellent opportunity for networking between like-minded process scientists of all levels of experience and from all areas of the chemical industry.
Programme

Day 1 - 11th April 2018

Event Schedule
11:00
Registration and refreshments
12:15
Lunch and exhibition Please note: Bedrooms at the college will be available from 14:00 onwards CHAIR: Dr Alan Robinson, Syngenta, Switzerland
13:25
Opening remarks
13:30
Developing, understanding and incorporating photomediated transformations in pharmaceutical development Dr Danielle Schultz, Merck Sharp and Dohme, USA
14:10
C-H functionalisation: oxidative carbon-heteroatom bond formation using base metal catalysis and oxygen Prof Bert Maes, University of Antwerp, Belgium
14:50
Use of sponge metal catalysts for the continuous hydrogenation of an aliphatic nitro group Dr Glynn Williams, GlaxoSmithKline, UK
15:30
Refreshment break and exhibition CHAIR: Dr David Lathbury, Astute Chemical Development Consulting Ltd, UK
16:10
Enabling preparation and use of dibromoformaldoxime via continuous processing Dr Edouard Godineau, Syngenta, Switzerland
16:50
Monitoring chemical changes during food sterilisation Dr James Marshall, Mars Petcare, UK
17:30
Closing remarks
17:45
Wine reception (sponsored by Chrialquest) and exhibition
19:00
Dinner for residents (Churchill college dining hall)

Day 2 - 12th April 2018

Event Schedule
09:00
Catalytic asymmetric dearomatization (CADA) reactions Prof Shu-Li You, Shanghai Institute of Organic Chemistry, (SIOC), China
09:40
The manufacture of a process surprises during the development of an aliskiren intermediate Dr Thomas Allmendinger, Novartis, Switzerland
10:20
Refreshment break and exhibition CHAIR: Mr Robert Walton, Pfizer Ltd, UK
10:50
Process development challenges in the manufacture of synthetic peptides Dr Alastair Hay, Almac, UK
11:30
Fluorination technology development in the agrichemical industry Dr Linhua Wang, Syngenta, USA
12:10
Lunch and exhibition CHAIR: Dr David Pascoe, GlaxoSmithKline, UK
13:10
Case study - Safety Dr Andy Payne, GlaxoSmithKline, UK
14:30
Potent compound manufacturing at pilot plant scale. Development of a method for production of the cytostatic agent melflufen Dr Johan Wennerberg, Magle Chemoswed, Sweden
15:10
Refreshment break and exhibition CHAIR: Dr Louis Diorazio, AstraZeneca, UK
1540
Large-scale manufacturing of the PI3K beta-sparing inhibitor taselisib Dr Remy Angelaud, Genentech, USA
16:20
AstraZeneca, GlaxoSmithKline, Pfizer & Syngenta prize for process chemistry research 2018 Selective Direct Fluorination Strategies Prof Graham Sandford, Durham University
17:20
Closing remarks
17:30
Wine Reception (sponsorsed by Johnson Matthey) and exhibition
1900
Symposium dinner (Churchill college dining hall)

Day 3 - 13th April 2018

Event Schedule
09:00
Development of a sustainable and scalable process for step 1 and 2 of talazoparib tosylate Mr Craig Knight, Pfizer, UK
09:40
Development of a commercial route to the reversible BTK inhibitor BMS-986142-01 Dr Steven Wisniewski, BMS, USA
10:20
Refreshment break and exhibition CHAIR: Dr Andy Wells, Charnwood Technical Consulting Ltd, UK
10:50
Lesinurad - following the science to a treatment for Gout Dr Alexandra Parker, AstraZeneca, UK
11:30
Case Study Dr John Pavey, UCB, UK
12:10
Symposium close
Venue and Contact

Churchill College

Storey’s Way
Cambridge
CB3 0DS
UK

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org

Fees

Early bird fees before Friday 26 January 2018

GB£370 . . . . . . . . . . . . . . . . . SCI Member
GB£255 . . . . . . . . . . . . . . . . . SCI Subsidised Member
GB£400 . . . . . . . . . . . . . . . . . Non-Member

Standard fees after Friday 26 January 2018

GB£540 . . . . . . . . . . . . . . . . SCI Member
GB£280 . . . . . . . . . . . . . . . . SCI Subsidised Member
GB£595 . . . . . . . . . . . . . . . . Non-Member

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Booking Process/Deadlines
For booking terms and conditions click here.
CPD Info

SCI Members attending this meeting are able to claim CPD points.

Accredited cpd Centre - The CPD Standards Office - CPD Provider 41057 - www.cpdstandards.com

Sponsors
Johnson Matthey Logo
Chiral Quest
American Elements, global manufacturer of high purity chemicals & reagents for process development and R&D in the pharmaceutical, engineering, biotech & chemical manufacturing industries
Additional Info

Accommodation

To book accommodation, please contact the accommodation office on 01223 336164 or email accommodation@chu.cam.ac.uk

For those who have already booked accommodation, please download and complete the guest registration form. You will need to hand this in when you arrive at the Porters' lodge.