27 March - 29 March 2019
36th SCI Process Development Symposium
Organised by:
SCI's Fine Chemicals Group
Cambridge, UK
Synopsis
Process Development is the application of chemistry to the scale up of new synthetic processes from the laboratory, through pilot plant to full scale commercial manufacture and into life cycle management. It is an extremely broad discipline, crossing the boundaries between synthetic organic chemistry, process technology and chemical engineering.
The area of Process Development continues to be a challenging and important area for the research into and application of modern synthetic organic chemistry, as well as enabling technologies.Attendees
The symposium aims to bring together a wide range of speakers from across the Pharmaceutical, Agrochemical and Fine Chemical industries, as well as from an academic background. This meeting brings together experts from across the entire spectrum of the discipline to present state of the art process development. As an established and well attended meeting, the process development symposium offers an excellent opportunity for networking between like-minded process scientists of all levels of experience and from all areas of the chemical industry.Wednesday 27 March 2019
| 11.00 | Registration and refreshments | |
| 12.15 | Lunch | |
| CHAIR: David Pascoe, GlaxoSmithKline, UK | ||
| 13.25 | Opening remarks | |
| 13.30 |
Approaches to Synthesis and Scale-up of a Wee-1 Kinase Inhibitor |
|
| 14.10 |
Novel industrial applications for electrochemistry - expecting the unexpected |
|
| 14.50 |
Homogeneous catalysis research @ BASF: A new Pd-catalyzed low pressure carbonylation |
|
| 15.30 | Refreshment break and exhibition | |
| CHAIR: Stella James, Bionow, UK | ||
| 16.10 |
New catalytic strategies for complex alkyl amine synthesis |
|
| 16.50 |
MK-8591 — development of an enzymatic cascade for commercial manufacture |
|
| 17.30 | Closing remarks | |
| 17.45 | Wine reception sponsored by Chiralquest | |
| 19.00 | Dinner for residents |
Thursday 28 March 2019
| CHAIR: David Lathbury, Astute Chemical Development Consulting Ltd, UK | ||
| 09.00 |
Total synthesis of polycyclic natural products |
|
| 09.40 |
Some process development aspects of industrial fluorine chemistry |
|
| 10.20 | Refreshment break and exhibition | |
| CHAIR: Rob Walton, Pfizer, UK | ||
| 10.50 |
Authorisation: Aprotic solvents and the pharmaceutical industry |
|
| 11.30 |
Scaling up Photoredox Reactions via Flow Chemistry |
|
| 12.10 | Lunch and exhibition | |
| 13.10 |
Leveraging integrated technology platform and intimate partnership in innovative API development and manufacturing |
|
| 13.50 |
Flow chemistry, an enabling technology in Pharma |
|
| 14.30 |
Impurity evaluation — current areas of interest and future challenges |
|
| 15.10 | Refreshment break and exhibition | |
| CHAIR: Alan Robinson, Syngenta, Switzerland | ||
| 15.40 |
Making a difference to malaria sufferers throughout the world – Process development of Tafenoquine Succinate |
|
| 16.20 | Process Chemistry Award winner 2019: Mechanistic investigations driving catalyst development: solving reactions of industrial relevance through academic curiosity Prof Ian Fairlamb, University of York, UK |
|
| 17.20 | Closing remarks | |
| 17.30 | Wine reception sponsored by Johnson Matthey | |
| 19.00 | Conference dinner |
Friday 29 March 2019
| CHAIR: Louis Diorazio, AstraZeneca, UK | ||
| 09.00 |
ERK Inhibitor LY3214996 Development and Route Selection (ERK = extracellular signal-regulated kinases) |
|
| 09.40 |
ReactIR and FBRM in manufacturing process development |
|
| 10.20 | Refreshment break and exhibition | |
| 10.50 |
Scaling Up of Continuous Flow Processes for Active Pharmaceutical |
|
| 11.30 |
The JAK3 Inhibitor PF-06651600 – Commercial Route Identification |
|
| 12.10 | Conference close |
Venue and Contact
SCI
Storey’s Way
Cambridge
CB3 0DS
Conference Team
Tel: +44 (0)20 7598 1561
Email: conferences@soci.org
Fees
Early bird fees before Friday 1 February 2019
| £375 | SCI Member | |
| £260 | SCI Subsidised Member | |
| £420 | Non-Member |
Standard fees after Friday 1 February 2019
| £495 | SCI Member | |
| £290 | SCI Subsidised Member | |
| £550 | Non-Member |
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CPD Info
SCI Members attending this meeting are able to claim CPD points.
Sponsors
Additional Info
Accommodation
Accommodation can be booked for delegates at the college in single study ensuite or standard bedrooms. Bedrooms will be allocated on a first come, first served basis.
The accommodation package is for 2 nights - Wednesday 27 and Thursday 28 March and includes full English or Continental breakfast. Rooms must be vacated by 10.00am on the day of departure. To make a reservation, please click here.
Please note: Bedrooms at the college will be available from 14.00 on the day of arrival. Those not wishing to stay in college accommodation can book accommodation directly through www.visitcambridge.org.
Exhibition and Sponsorship
An exhibition will run alongside the conference during refreshment breaks, for companies and related organisations who may wish to exhibit. For further information and prices please email jacqui.maguire@soci.org
Organising Committee
- Dave Lathbury, SCI/Astute Chemical Development Ltd
- David Pascoe, SCI/GlaxoSmithKline
- Robert Walton, SCI/Pfizer
- Louis Diorazio, SCI/AstraZeneca
- Stella James, SCI/Bionow
- Alan Robinson, SCI/Syngenta
- Steven Oliver, Merck Sharp & Dohme
- Andy Wells, Charnwood Technical Consulting Ltd