22 October 2014

Introduction to Epigenetic Drug Discovery

Organised by:

SCI’s Young Chemists' Panel

Nuffield Department of Medicine Research Building, Oxford, UK

Registration Closed

This event is no longer available for registration.

Epigenetics is a rapidly expanding area of research whose importance for the generation of novel therapeutics is becoming increasingly apparent.

This is the second meeting organised by SCI's Young Chemists' Panel covering this emerging area of drug discovery. The aim of the day is to provide participants with a fundamental understanding of Epigenetics and how it relates to Drug Discovery, from an introduction to the underpinning biology and the discovery of novel therapeutic targets to the development of chemical probes and small molecule inhibitors. The day will comprise of a series of lectures from some of the leading names in Epigenetic research from both UK academia and industry. The day will close with a question and answer session which all of the speakers will be involved in.

The meeting is aimed at those studying for a postgraduate degree in the area of medicinal chemistry or working in pharmaceutical or biotechnology industries, in particular those wishing to gain a greater understanding of the fundamental aspects of this emerging area of drug discovery.


Day 1

Registration and refreshments
Welcome and introduction
Epigenetic drug discovery - why it matters and why it’s tough
Nessa Carey, PraxisUnico
Selective targeting of protein interactions mediated by epigenetic reader domains
Stefan Knapp, SGC
Synergy of multiple hit identification approaches and structural biology to find epigenetic modulators
Chun-wa Chung, GlaxoSmithKline
Developing inhibitors of the bromodomain-histone interaction
Stuart Conway, University of Oxford
The KDM5 histone demethylases as targets in drug discovery
Peter Staller, Epitherapeutics
The design and synthesis of selective Peptidyl Arginine Deiminase 4 (PAD4) tool inhibitors
Stephen Atkinson, GlaxoSmithKline
Paul Brennan, SGC
Closing remarks and wine reception
Accessibility Grants

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Venue and Contact

Structural Genomics Consortium

Nuffield Department of Medicine Research Building
University of Oxford
Old Road Campus
Oxford, OX3 7FZ


Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org

SCI Member GB£80
SCI Student Member GB£30
SCI Subsidised Member GB£55
Non-Member GB£110

Standard Rate - after 12 September 2014

SCI Member GB£100
SCI Student Member GB£35
SCI Subsidised Member GB£65
Non-Member GB£130

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Booking Process/Deadlines
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Additional Info

Organising Committee

Ben Buckley, Loughborough University
Tom Hayhow, GlaxoSmithKline
Michael Lainchbury, Argenta
Ben Whittaker, Biofocus