23 January 2018
Ketamine, Glutamate and Brain Imaging
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UCL, London, UK
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Synopsis
The recent interest in the potential for ketamine as an antidepressant has led to speculation about the possible mechanisms that might underlie this effect. Although they do not permit the study of intracellular mechanisms, neuroimaging methods allow the study of biologically relevant changes in brain function and neurochemistry, which may help to elucidate the processes underlying the therapeutic benefit of ketamine in patients with depression. In this presentation, I will discuss current theories about the biological underpinnings of the antidepressant effects of ketamine. I will discuss the acute and subacute effects of ketamine on brain glutamate levels, as measured using proton magnetic resonance spectroscopy. I will also discuss ketamine effects on functional connectivity, blood flow and neuroreceptor binding, and consider how these might be related to its antidepressant properties.Venue and Contact
UCL
Department of Chemistry
University College London
20 Gordon Street
London, WC1H 0AJ
SCI Communications Team
Tel: +44 (0) 20 7598 1594
Email: communications@soci.org
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This is a FREE event. No need to book. Please check this page for any updates or changes before attending the event.
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