16 January - 17 January 2013

Protein-Protein Interactions: Emerging Science and Therapeutic Potential

Organised by:

An international multidisciplinary two-day conference organised jointly by PPI-net, BMCS, MGMS and SCI

London

Registration Closed

This event is no longer available for registration.

Attendees
International academics and industrialists engaged in the research of protein-protein interaction.
Programme

16 january

Event Schedule
10:00
Registration and refreshments
10:45
Welcome
1100
Fragments: a good first step towards modulating protein-protein interactions Chris Abell, University of Cambridge, UK
1100
Controlling cell fate with PPI-targeting biophotonic nanoswitches Rudolf Allemann, Cardiff University, UK
12:00
Protein-protein interaction inhibitors of transcription factors and enzymes Thorsten Berg, University of Leipzig, Germany
12:30
Lunch and posters
13:45
Protein-protein interactions as drug targets: time to reach for the barge pole? Alex Breeze, AstraZeneca, UK
14:15
3 x 15 Minute short talks
15:00
Molecular insights and targeting of Nuclear Receptor - protein interactions Luc Brunsveld, Eindhoven University of Technology, The Netherlands
15:30
Refreshments
15:50
Drug-like inhibitors of protein-protein interactions: peptide mimicry and fragment approaches David Fry, Hoffman-La Roche Inc, USA
16:20
Protein-protein interaction and drugs - a resolvable paradox? Mike Hann, GlaxoSmithKline, UK
16:50
Combining drug-discovery approaches to tackle challenging targets Michelle Arkin, University of California San Francisco, USA
17:40
Wine reception and poster prizes

17 January

Event Schedule
09:00
Structural networks of signalling pathways on the cellular scale Ruth Nussinov, National Cancer Institute, SAIC-Frederick, USA
09:50
Approaches to the discovery of small-molecule MDM2-p53 inhibitors Ian Hardcastle, Newcastle University, UK
10:20
Refreshments
10:40
Selective targeting of epigenetic effector domains of the bromodomain family Stefan Knapp, Oxford University, UK
11:10
Structure-based guided development of focused chemical libraries dedicated to orthosteric modulation of protein-protein interactions Xavier Morelli, Centre National de la Recherche Scientifique, France
11:40
Small molecule modulation of 14-3-3 protein-protein interactions Christian Ottman, Technical University Eindhoven, The Netherlands
12:10
Lunch and posters
13:25
Exploring protein-protein interactions in the malaria parasite Ed Tate, Imperial College London, UK
13:55
3 x 15 Minute short talks
14:40
Refreshments
15:00
Inhibition of protein-protein interactions using designed molecules Andrew Wilson, University of Leeds, UK
15:30
Fragment-based approches to protein-protein interaction targets: discovery of antagonists and allosteric modulators Christopher Johnson, Astex Pharmaceuticals, UK
16:00
Inhibition protein-protein interactions with peptidic foldamers Sam Gellman, University of Wisconsin Madison, USA
16:50
Close
Accessibility Grants

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Venue and Contact

The Royal Society

The Royal Society, 6-9 Carlton House Terrace, London, SW1Y 5AG, UK
Please click here for a location map.
The nearest tube stations are Charing Cross (Northern and Bakerloo lines) and Piccadilly Circus (Piccadilly and Bakerloo lines).

PPI Conference Team

Tel: +44 (0)20 7598 1561

Email: conference@ppi-net.org

Fees

Earlybird fees - before 16 December 2012

Standard delegate fee.......GB£200
Student* delegate fee.......GB£110 
* Undergraduates and PhD students only (not post-graduates)

Standard fees - after 16 December 2012

Standard delegate fee.......GB£250
Student* delegate fee.......GB£150 
* Undergraduates and PhD students only (not post-graduates)

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Booking Process/Deadlines

Booking terms and conditions

CPD Info

SCI Members attending this meeting are able to claim CPD points.

Accredited cpd Centre - The CPD Standards Office - CPD Provider 41057 - www.cpdstandards.com

Additional Info

Student travel grants

PPI-net will award a limited number of travel bursaries to UK students in the field of PPI.
In addition, the Molecular Graphics and Modelling Society (MGMS) will sponsor the attendance of two computational students.

Sponsors

GlaxoSmithKline
Eisai
RSC Bioorganics Group
MGMS

Exhibition

A limited number of exhibition stand spaces are available at a rate of GB£800. Please contact conference@ppi-net.org if you would like to be included in the exhibiton.