Young Chemist in Industry 2016

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10:00

Registration and refreshments

10:30

Introduction

10:35

Optimisation of a series of potent and selective GR antagonists Benoit Gourdet, Sygnature Discovery

11:00

Fluorocompounds in cement - ‘bringing science to the sell’ Sheryl Johnson, Mexichem

11:25

Refreshment break

11:45

Synthetic approaches to a [1.1.1] bicyclopentane and its incorporation into darapladib as a phenyl bioisostere Nicholas Measom, GlaxoSmithKline

12:10

The development of novel smoothened inhibitors with improved aqueous solubility and potential use as orally or topically administered anti-cancer agents Louise Sargent, RedX Oncology

12:35

Lunch

13:30

Studies towards palladium sp3 C-H activation of tetraalkyl piperazine-based scaffolds Thomas Alanine, AstraZeneca

13:55

Tentoxin: exploring small cyclic peptides as herbicides Elizabeth Frye, Syngenta

14:20

Osimertinib mesylate: process development and scale-up of an API on the critical path Shaun Hughes, AstraZeneca

14:45

Refreshment break

15:10

N-Functionalisation of tertiary amines powered by visible light Joshua Barham, GlaxoSmithKline

15:35

Plenary talk: discovery and characterisation of potent and selective inhibitors of ATR kinase as anti-cancer agents Joanne Pinder, Vertex

16:20

Prize giving followed by wine reception