12 November - 13 November 2018

2nd SCI/RSC Symposium on Antimicrobial Drug Discovery

Organised by:

SCI's Fine Chemicals Group and RSC's Biological and Medicinal Chemistry Sector

London, UK

Registration Closed

This event is no longer available for registration.

Synopsis

Rising antimicrobial resistance is decreasing the efficacy of existing treatments for infection. With the alarming prospect of a post-antibiotic era, it is vital that we refresh the drug pipeline with new therapies and therapeutics that act through novel modes of action. With pressure from governments and increased public awareness of this growing problem, renewed interest from industry and academia has led to a resurgence in antimicrobial drug discovery, with the exciting prospect of new and innovative technologies and approaches for combating infection.

Following the first successful event in 2016, this meeting will examine the current state of the art in antimicrobial drug discovery from a medicinal chemist's perspective. Coinciding with World Antibiotics Awareness week, a two-day programme of speakers from industry and academia wil highlight the challenges associated with discovering and developing new antimicrobials, whilst also showcasing emerging strategies that are being developed to tackle infection.


Attendees
Bringing together leading exponents in the field from industry and academia, the meeting will appeal to anyone with an interest in antimicrobial resistance and antimicrobial drug discovery. With great opportunities for academic-industrial partnerships, researchers from both sectors will also benefit from the networking opportunities that the meeting will offer.
Programme
12:00 Registration, exhibition and lunch
   
13:00 Opening remarks
   
13:10 Antibiotics: challenges and opportunities
Dr Stephen Baker, GlaxoSmithKline
   
13:55 Rational and irrational discovery of novel interventions to treat drug-resistant infections
Prof Matt Cooper, University of Queensland and Inflazome
   
14:40 Flash poster presentations
   
15:00 Refreshment break and exhibition
   
15:30 Towards photopharmacological antimicrobial chemotherapy
Dr Matthew Fuchter, Imperial College London
   
16.00 SPARKing new antibiotic discovery
Wes Kim, The Pew Charitable Trusts
   
16:30 Research and development of new antimicrobial drugs and combinations: a not-for-profit approach
Prof Laura Piddock, Global Antibiotic Research & Development Partnership
(GARDP)
   
17:15 Networking and refreshments
   

Tuesday 13 November

09:00 Rules for bacterial penetration - what we know and what we don't
Dr Paul Finn, Oxford Drug Design
   
09:30 Reversing efflux-mediated resistance to reinvent broad-spectrum antibiotics
Dr K Miraz Rahman, King's College London
   
10:00 Predictive guidelines for compound accumulation lead to new broad-spectrum antibiotics
Prof Paul Hergenrother, University of Illinois
   
10:45 Refreshment break and exhibition
   
11:15 Non-hydroxamate LpxC inhibitors
Dr Alastair Parkes, Evotec
   
11:45 Novel immunotherapeutics to target Gram-negative bacterial infections
Dr Emma Leire, Centauri Therapeutics
   
12:15 Analysis of potassium (K+) efflux systems (Kef) as an antibiotic target in pathogenic bacteria
Catherine Haslam, University of Oxford
   
12:30 Turning strength into a weakness: exploiting resistance as a novel therapeutic target
Lindsay Evans, Imperial College London
   
12:45 MAPS: Multiparameter Assay for Profiling Susceptibility
Dr Lisa Miller, University of York
   
13:00 Lunch and exhibition
   
14:00 Short antimicrobial peptides - their potential against multidrug resistant bacteria
Dr Kai Hilpert, St George's, University of London
   
14:30 From HTS to preclinical candidate: a novel small-molecule antibiotic for the treatment of drug-resistant Neisseria gonorrhoeae
Dr Paul Meo, Summit Therapeutics
   
15:00 Refreshment break and exhibition
   
15:30 Metallo β-lactamase inhibitors: an approach to combat the threat of emerging carbapenem resistance due to metallo β-lactamase enzymes in Gram-negative bacteria
Dr David Davies, AntaBio
   
16:00 Challenges in antibacterial drug discovery
Prof Ian Gilbert, University of Dundee
   
16:45 Closing remarks

Venue and Contact

SCI

14/15 Belgrave Square
London
SW1X 8PS

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org


Fees

Early bird fees before Friday 5 October 2018

£150 SCI / RSC Member
£50 SCI / RSC Student Member
£100 SCI / RSC Subsidised Member
£180 One Nucleus Member
£200 Non-Member

 

Standard fees after Friday 5 October 2018

£180 SCI / RSC Member
£60 SCI / RSC Student Member
£120 SCI / RSC Subsidised Member
£220 One Nucleus Member
£240 Non-Member

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Booking Process/Deadlines
For booking terms and conditions click here.
Partners

Exhibitors

Sponsors

Additional Info

Call for Abstracts for Short Talks from Early Career Researchers

Early career researchers wishing to give a short talk (10 minutes) are encouraged to submit a one-page abstract to conferences@soci.org by Friday 15 June 2018 with "AMR short talk abstract" in the subject line. Unsuccessful applicants will automatically be considered to present a poster.

Call for Poster Abstracts

Anyone wishing to present a poster should submit a one-page abstract to conferences@soci.org by Friday 14 September 2018 with "AMR - poster abstract" in the subject line. Selected poster presenters will be given the opportunity to give a flash presentation.

Bursaries

A limited number of bursaries are available to SCI/RSC student members to cover their registration fees and contribute to their travel and accommodation costs. To apply for a bursary, please send an email to conferences@soci.org by Friday 14 September 2018 with "AMR II - bursary application" in the subject line.

Exhibition and Sponsorship

An exhibition will take place alongside the conference. Companies and related organisations who may wish to exhibit, please email conferences@soci.org for further information and prices. Spaces are limited and will be allocated on a first-come, first-served basis.

Organising Committee

  • Dr Liam Cox, SCI / University of Birmingham
  • Dr Caroline Low, SCI / Computational Medicinal Chemistry Consultant
  • Dr Sarah Major, SCI / Evotec (UK) Ltd
  • Dr Pascal Savy, SCI / Charles River Laboratories
  • Dr Francis Wilson, RSC / Summit Therapeutics

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