21 April - 22 April 2020

3rd SCI-RSC Symposium on Transporters in Drug Discovery and Development

Organised by:

SCI's Fine Chemicals Group, RSC’s Biological and Medicinal Chemistry Sector and the Drug Metabolism Discussion Group (DMDG)

London, UK

Synopsis

Cell surface transporters play a key role in human health and disease, both through their impact on drug disposition and as therapeutic targets in their own right. This third meeting in the series will feature talks on transporter structural biology, the impact of transporters on ADME and biodistribution, transporters as therapeutic targets and other aspects of transporters relevant to drug discovery and development


Attendees
Bringing together leading exponents in the field from industry and academia, the meeting will appeal to medicinal chemists, DMPK scientists and other workers interested in the impact of transporters on human health. 

Programme
Tuesday 21 April
12.00
Registration and lunch
13.00
Opening remarks
13.10
The evolution of transporters in drug discovery
Anna-Lena Ungell, UCB, UK
14.00
New model for P-gp and CNS at the blood-brain barrier
Mohammed Ullah, Roche, Switzerland
14.50
Refreshment break, exhibition and posters
15.20
SLC transporters as drug targets
Graham Belfield, AstraZeneca, Sweden
16.10
UCB Plenary Lecture: Genomics of transporters – informing drug development
Kathy Giacomini, UCSF, USA
17.10
Networking reception, exhibition and posters
18.00
Close
Wednesday 22 April
09.00
PBPK of transporter-mediated hepatic disposition using the imaging biomarker gadoxetate
Daniel Scotcher, University of Manchester, UK
09.50
Transporter PBPK modelling and DDI
Venkatesh Pilla Reddy, AstraZeneca, UK
10.40
Refreshments, exhibition and posters
11.10
TBC
11.35
TBC
12.00
Heteromeric amino acid transporters: disease and structure
Manuel Palacin, Institute for Research in Biomedicine, Spain
12.30
Lunch, exhibitors, posters
14.00
Structural insight into substrate and inhibitor interactions with human multi-drug transporters ABCB1 and ABCG2
Kaspar Locher, ETH Zurich, Switzerland
14.50
Strategies for the pharmacological modulation of ABC transporters
Christopher Koth, Genentech, USA
15.40
Malarial transporters
Jeremy Burrows, Medicines for Malaria Venture, Switzerland
16.30
Closing remarks

Venue and Contact

SCI

14/15 Belgrave Square
London
SW1X 8PS

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org


Fees
Early bird fees before Tuesday 10 March 2020
£170
SCI / RSC / DMDG Member
£60
SCI / RSC / DMDG Student Member
£105
SCI / RSC / DMDG Subsidised Member
£215
Non-Member
Standard fees after Tuesday 10 March 2020
£240
SCI / RSC / DMDG Member
£85
SCI / RSC / DMDG Student Member
£150
SCI / RSC / DMDG Subsidised Member
£300
Non-Member

If you are an RSC / DMDG member and would like to register for this event, please first contact conferences@soci.org referencing the event name, your full name, organisation and RSC / DMDG member number.


Bursaries

A limited number of bursaries are available to students to cover their registration fees and contribute to their travel and accommodation costs. To apply, please complete and return this form to conferences@soci.org by Friday 20 March.

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Booking Process

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Partners

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Call for abstracts

An abstract of maximum one A4 page or 300 words, indicating title, authors and preference for presentation option (oral or poster) should be sent to conferences@soci.org by Monday 9 March 2020 with the subject line “Transporters – abstract submission”. An abstract template can be downloaded here.


Exhibition and Sponsorship

An exhibition will take place alongside the conference during refreshment breaks for companies and related organisations who may wish to exhibit. For further information and prices, please email conferences@soci.org. Spaces are limited and will be allocated on a first come, first served basis.


Organising Committee
  • Emmanuel Callens, Selcia
  • John Cumming, Roche
  • Jamie Henshall, UCB
  • Fabien Lecomte, UCB
  • Martin Lowe, UCB
  • Mohammed Ullah, Roche