22 June 2021

FCG/YCP Webinar Series III

Organised by:

SCI’s Fine Chemicals Group and Young Chemists’ Panel

Online Webinar 15.00 - 16.15 BST

Registration Closed

This event is no longer available for registration.

Synopsis
The SCI’s Fine Chemicals Group and Young Chemist’s Panel are pleased to invite you to join our programme of webinars to support constant development and inspire chemists in industry and academia. This series of online sessions will be held weekly during June 2021 and will encompass a range of topics, demonstrating high quality chemistry in a format accessible worldwide. Talks from industrial and academic speakers will be jointly contributing on exciting developments in catalysis, biocatalysis, continuous flow processing and medicinal chemistry. 

Sign up for what promises to be an engaging series of talks!

Further information and videos from the previous webinar series are available here.
 

Speakers
Hosea Nelson

Hosea Nelson

UCLA

Prof Nelson began his academic career at City College of San Francisco. He then earned a B.S. in Chemistry from University of California at Berkeley in 2005 and a Ph.D. from the California Institute of Technology in 2013. After postdoctoral training at University of California at Berkeley, Prof. Nelson joined the UCLA faculty in 2015. Broadly speaking, Prof. Nelson’s research program is focused on the development of enabling technologies for chemical synthesis. His group approaches this goal through several research areas including reaction discovery, electron crystallography, biocatalysis and total synthesis.

Katherine Wheelhouse

Katherine Wheelhouse

GSK

Katherine Wheelhouse studied for her MChem at Jesus College, Oxford, graduating in 2004; her MChem project was carried out under the supervision of Professor Tim Donohoe in the area of ring-closing metathesis for heterocycle synthesis. She stayed in the Donohoe group for a DPhil, working on osmium-mediated oxidative cyclisation reactions before joining GSK as a process chemist in 2008. Since 2011 Katherine has specialised in application of chemical cataysis to pharmaceutical manufacture, working on projects across all stages of development. She is a GSK scientific fellow, a member of the RSC Applied Catalysis Committee, the PharmaCat Industrial Steering Committee and also of the editorial advisory board of the journal Organic Process Research and Development.

John McIntosh

John McIntosh

MDS

MSD

John McIntosh studied his PhD in Eric Schmidt’s laboratory at the University of Utah, where he studied the biosynthesis of the cyanobactin family of cyclic peptide natural products. After finishing graduate school he pursued his post doctorate for Frances Arnold at Caltech where he studied non-natural reactions of cytochrome P450s and other heme proteins. John has been part of the MSD’s Small-Molecule Process Research and Development Department since 2015 where he has worked in the Biocatalysis and Protein Engineering groups. He is presently an associate principal scientist.

Anne Foley

Anne Foley

UCB

UCB

I am a Senior Scientist in the Medicinal Chemistry Department at UCB, UK working on early and late stage NCE programs. I joined UCB after completing a DPhil at Oxford University with Prof. David Hodgson on Alkene Selective Ring-Closing Metathesis and Chromium(II)-Mediated E-Alkenylstannylation. Before my DPhil, I worked at AZ, Loughborough in the Research Analytical Group. Whilst at UCB, I have worked on numerous NCE projects within multiple therapeutic areas, including oncology and inflammation including kinase, integrin and PPI inhibitor programs, such as TNF-α, successfully delivering candidates into development. Outside the lab, I enjoy taking part in STEM outreach activities and inspiring young people.

Chloe Townley

Chloe Townley

Astex

astex pharmaceuticals logo

Chloe completed her PhD from the university of Leeds in 2020 under the supervision of Prof’s Adam Nelson, Steve Marsden and Dr Lindsay McMurray (AstraZeneca).
She joined Astex in summer 2020 as a medicinal chemist and is currently working in the synthesis and technology group.

Julie Shanu

Julia Shanu Wilson

Hypha Discovery

Julia earned her degree and PhD in biochemistry from Imperial College London. Her PhD focussed on the discovery of microbial alkaloids using radiolabelled probes.
Following a post doc in New Zealand on the biosynthesis of indole diterpenoids, Julia joined the pharmaceutical industry as a Research Scientist, becoming a Programme Discovery Leader for Cubist Pharmaceuticals (subsequently bought by Merck). She was responsible for the team discovering new natural product derived anti-bacterial drugs, and was part of the cross-continent team responsible for bringing daptomycin to the market. Julia joined Hypha in 2013 and is on the Management Team.

Oliver Kappe

Oliver Kappe

University of Graz, Austria

Oliver Kappe is Professor of Chemistry at the University of Graz (Austria) and Scientific Director of the Center of Continuous Flow Synthesis and Processsing (CC FLOW). He received his diploma (1989) and his doctoral (1992) degrees in organic chemistry from the University of Graz and after two postdoctoral stays (University of Queensland and Emory University) returned to Graz in 1996 to start his indepenent acacdemic career and was appointed Full Professor in 2011. For the past decade the focus of his research has been directed towards flow chemistry/microreaction technology, encompassing a wide variety of synthetic transformations and experimental techniques. His research group is actively involved in projects dealing with API synthesis and manufacturing, employing a number of different enabling and process intensification strategies.


Programme

Tuesday 1 June

Topic: Catalysis
Talk 1:
Twists and turns along the path of reactivity-driven methods development
Prof Hosea Nelson, UCLA
Talk 2:
Industrialisation of chemical catalysis at GSK
Katherine Wheelhouse, GSK

Tuesday 8 June

Topic: Biocatalysis/Covid
Talk 1:
Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19
John McIntosh, MSD
Talk 2:
Hydroxylating drugs; not too late in the game for enzymes?
Dr Julia Shanu-Wilson, Hypha Discovery

Tuesday 15 June

Topic: Flow
Talk 1:
Enhancing the Efficiency of Organometallic Transformations Using Microreaction Technology
Prof Oliver Kappe, University of Graz, Austria
Talk 2:
Flow Chemistry in Drug Discovery as a tool to escape from flatland
Dr Jesus Alcazar, Janssen Pharmaceutical

Tuesday 22 June

Topic: Medchem/synthesis
Talk 1:
Discovery of Novel Small Molecule Modulators of TNFα Binding and Signalling
Dr Anne Foley , UCB
Talk 2:
Enabling Synthesis in Fragment-based Drug Discovery with Emerging Technologies
Dr Chloe Townley, Astex

Fees

SCI members: Free
SCI student members : Free
Non-members: £50 

Please note that fees are for the four webinars and cannot be changed to accommodate one or two webinars.

Corp Partners and SMEs
Employees of SCI Corporate and SME Partner organisations are entitled to attend these webinars free of charge. If you work for an SCI Corporate or SME Partner organisation and are not yet registered as an SCI member, contact membership@soci.org prior to registering for this event to upgrade your account.

Not sure if your organisation is an SCI Corporate or SME Partner?  Please see a list here or contact us to find out more: membership@soci.org

Membership
Sign-up for SCI membership today and you can attend FCG/YCP Series III free of charge. Your membership entitles you to a range of benefits including free or discounted access to our calendar of upcoming events, such as the following organised by SCI’s Fine Chemical Group and Young Chemists’ Panel:
What’s New in Immunotherapies 2021
New Approaches in Medicinal Chemistry 2021

If you need any assistance to sign-up for membership, please contact membership@soci.org

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Booking terms and conditions


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Contact

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org