29 March - 31 March 2023

39th SCI Process Development Symposium

Organised by:

SCI's Fine Chemicals Group

Churchill College, Cambridge, UK

Register for this event

Prices start from £395.00

Early bird offer ends 16 February 2023

Synopsis

Process Development is the application of chemistry to the scale up of new synthetic processes from the laboratory, through pilot plant to full scale commercial manufacture and into life cycle management. It is an extremely broad discipline, crossing the boundaries between synthetic organic chemistry, process technology and chemical engineering.

The area of Process Development continues to be a challenging and important area for the research into and application of modern synthetic organic chemistry, as well as enabling technologies.  


Attendees

The symposium aims to bring together a wide range of speakers from across the Pharmaceutical, Agrochemical and Fine Chemical industries, as well as from an academic background. This meeting brings together experts from across the entire spectrum of the discipline to present state of the art process development. 


Accommodation

Accommodation can be booked for delegates at the college in single study ensuite or single study standard bedrooms. Single ensuite rooms have a private bathroom and single standard rooms have a shared bathroom.

Bedrooms will be allocated on a first come, first served basis. The accommodation package is for 2 nights – Wednesday 29 and Thursday 30 March and includes full English or Continental breakfast plus an evening meal on Wednesday 29 March. Rooms must be vacated by 10.00am on the day of departure. Those not wishing to stay in college accommodation can book accommodation directly through www.visitcambridge.org

Please note: Bedrooms at the college will be available from 14:00 on the day of arrival.


Exhibition and Sponsorship

For further information and prices, please email conferences@soci.org.


Programme

Wednesday 29 March

11:00
Registration and refreshments
12:15
Lunch and exhibition
CHAIRPERSON: Dr Hazmi Tajuddin, Syngenta, UK
13:25
Opening remarks
13:30
Process research and development of a herbicide candidate dioxopyritrione
Dr Helmars Smits, Syngenta, Switzerland
14:10
Title to be confirmed
Dr Ekaterina Melikhova, CatSci, UK
14:50
Route invention and scale up of a biotransformation
Dr Shane McKenna, BMS, UK
CHAIRPERSON: Dr Robert Walton, Pfizer, UK
16:10
Process enablement of COVID-19 oral inhibitor nirmatrelvir at unprecedented speed from milligrams to metric tons in 18 months
Dr Chris Allais, Pfizer Groton, USA
16:50
Your chemistry has got potential: highly reactive intermediates without the “bang”
Dr Kevin Lam, University of Greenwich, UK
17:30
Closing remarks
17:45
Wine reception sponsored by Chiralquest
19:00
Dinner for residents

Thursday 30 March

CHAIRPERSON: Dr Max Espensen, Pharmaron, UK
09:00
Title to be confirmed
Speaker from Pharmaron, UK
09:40
Title to be confirmed
Speaker from Pfizer, UK
10:20
Refreshment break and exhibition
CHAIRPERSON: Dr David Lathbury, Astute Chemical Development Ltd, UK
10:50
Case studies for stacked CSTRs: scalability and opportunities
Dr Nikolay Cherkasov, Stoli Chem
11:30
Discovery of AbbVie’s first-generation HCV protease inhibitor paritaprevir through process chemistry research
Dr Yi-Yin Ku, Abbvie, USA
12:10
Lunch and exhibition
CHAIRPERSON: Dr Hilmar Weinman, Janssen Pharmaceutical Companies of Johnson & Johnson, Belgium
13:10
Development of a scaleable transaminase process for highly volatile substrates
Dr Katharina Neufeld, Janssen Pharmaceutica N.V., Belgium
13:50
BAY 1163877 – complexity without chirality. A process R&D case study
Dr Joerg Griess, Bayer, Germany
14:30
Toward a safe and scalable preparation of 3-(3-methoxyisoxazol-5-yl)propanoic acid
Dr Cédric Bürki, Idorsia Pharmaceuticals Ltd, Switzerland
15:10
Refreshment break and exhibition
CHAIRPERSON: Dr Matt Burns, AstraZeneca, UK
15:40
Continuous processing for oligonucleotide building blocks
Dr Heena Panchal, AstraZeneca, UK
16:20
Process chemistry award winner 2022
17:20
Closing remarks
17:30
Wine reception
19:00
Symposium dinner

Friday 31 March

CHAIRPERSON: Dr Richard Horan, GlaxoSmithKline, UK
09:00
Development of a phosphorylative activation for the synthesis of BET inhibitor GSK525762
Miss Rhiannon Jones, GlaxoSmithKline, UK
09:40
Clinical manufacture of a high-potency API
Dr Stephen Bell, Almac, UK
10:20
Refreshment break and exhibition
10:50
Title to be confirmed
Dr Tiffany Piou, Merck, USA
11:30
Title to be confirmed
Speaker from Sai life sciences, UK
12:10
Conference close

Venue and Contact

Churchill College

Storey's Way
Cambridge
CB3 0DS

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org


Fees
Before early bird - ends 15 Feb 2023
SCI Member - £395
Non-member - £440
After early bird
SCI Member - £510
Non-member - £565

Standard accommodation (2 nights) - £190
Ensuite accommodation (2 nights) - £235

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Booking Process/Deadlines

Booking terms and conditions


Sponsors

Organising Committee
  • Max Espensen, SCI/Pharmaron

  • Richard Horan, SCI/GlaxoSmithKline

  • Dave Lathbury, SCI/Astute Chemical Development Ltd

  • Hazmi Tajuddin, SCI/Syngenta

  • Robert Walton, SCI/Pfizer

  • Hilmar Weinman, SCI/Janssen Pharmaceutical Companies of Johnson & Johnson

  • Matt Burns, SCI/AstraZeneca

Webpage photo kindly provided courtesy of Boehringer Ingelheim.