14 April - 15 April 2021
Organised by:
SCI's Fine Chemicals Group
Online Webinar
Day 1 - Wednesday 14 April
09:00 Welcome and introduction to day 1
09:05 Site-specific and enantioselective sp3 C-H functionalization
Prof Guosheng Liu, SIOC, China
09:50 Mechanistic work using at-line Mass spec
Dr Maria Ciaccia, Syngenta, UK
10:30 Break
10:50 Experimental design and its place in process development
Dr Laura Forfar, Catalysis Consulting Ltd, UK
11:35 Regioselective preparation and functionalization of azoles for the synthesis of active
pharmaceutical ingredients
Dr Diego Broggini, Janssen Pharmaceutical Companies of Johnson & Johnson, Switzerland
12:15 Lunch
13:15 Development of late-stage difluoromethylation methods for the synthesis of a CDK2/4/6 inhibitor
Dr Shengquan Duan, Pfizer, USA
14:00 Process development of a robust manufacturing route for sugammadex
Dr Sue Zultanski, Merck, USA
14:40 Break
15:00 Process development in the synthesis of CF corrector VX-661
Dr Cristian Harrison, Vertex pharmaceuticals, USA
15:45 Process chemistry award winner 2020: Design, development and applications of
catalytic synthesis methods based on phosphorus and silicon
Prof Ross Denton, University of Nottingham, Academic award winner, UK
16:25 Closing remarks
16:30 Close of the day
Day 2 - Thursday 15 April
09:00 Welcome and introduction to day 2
09:05 Particle design and modelling technologies for API manufacturing
Dr Claire Wombwell, Johnson Matthey, UK
09:50 New perspectives: approaches for the application of metal scavengers to impurity
control in pharma
Dr Sunil Rana, Biotage GB Ltd, UK
10:30 Break
10:50 Probing reagent / catalyst (dis)function
Prof Guy Lloyd Jones, University of Edinburgh, UK
11:35 The application of C-H functionalisation in the development of a concise and convergent route to nemiralisib
Dr Katherine Wheelhouse, GlaxoSmithKline, UK
12:15 Lunch
13:15 Right particle journey: crystallisation process development from labs to scale to
support drug product processing
Dr Rachel Sullivan, AstraZeneca, UK
14:00 An enantioselective total synthesis of (+)-duocarmycin SA
Dr Michael Schmidt, Bristol Myers Squibb, USA
14:40 Break
15:00 Automation and autonomy to enable process chemistry
Prof Jason Hein, University of British Columbia, Canada
15:45 Application of transition-metal catalysis, biocatalysis and flow chemistry as
state-of-the-art technologies in the synthesis of LCZ696
Dr Florian Kleinbeck, Novartis, Switzerland
16:25 Closing remarks
16:30 Close of the day
Before early bird (ends Monday 8 March) |
£150 SCI member |
£200 Non-member |
£75 student member |
After early bird |
£250 SCI member |
£310 Non-member |
£75 student member |
Sign up as an Event Member to join this event. SCI Full or Student Members receive discounts on event registrations
Louis Diorazio, SCI/AstraZeneca
Max Espensen, Pharmaron
Stella James, SCI/Bionow
Dave Lathbury, SCI/Astute Chemical Development Ltd
David Pascoe, SCI/GlaxoSmithKline
Hazmi Tajuddin, SCI/Syngenta
Robert Walton, SCI/Pfizer
Hilmar Weinman, Janssen Pharmaceutical Companies of Johnson & Johnson
Andy Wells, Charnwood Technical Consulting Ltd
For further information and prices please email jacqui.maguire@soci.org
Tel: +44 (0)20 7598 1561
Email: conferences@soci.org