17 October 2023
Exploring Chemical Space 2023
Organised by:
SCI's Fine Chemicals Group
SCI, London, UK
Synopsis
Chemical space is vast and affords nearly unlimited opportunities to develop novel functional molecules. This meeting seeks to explore how computational chemistry and synthetic methodology can be used to rapidly explore chemical space and create new opportunities to solve problems in organic chemistry, drug discovery and agrochemicals.
In 2011, we first brought researchers together to share their insights and discoveries in how to tackle chemical space exploration. In the years since, there has been significant progress in the field with developments in computational chemistry, identification and optimisation of novel bioactive molecules, beyond rule-of-5 compliant chemical space and much more. 12 years later we are again engaging leading industrial and academic speakers to explore and discuss their state-of-the-art science.
Attendees
This event will be of interest to academic and industrial chemists with an interest in identifying novel functional molecules. The topics covered will be relevant to both early career and established scientists looking to apply new techniques and approaches in their research.
Call for Posters
Contributions are invited for posters. An abstract of maximum 250 words (does not include author names, affiliations, references or figure captions) indicating title, authors, institution included with the poster, should be sent to conferences@soci.org by Monday 17 July 2023 with the subject line “Exploring Chemical Space - poster abstract”. You can download an abstract template here.
Programme
Tuesday 17 October 2023
- 09:30
- Registration and refreshments
- 10:00
- Application of emerging synthetic technologies to fragment based drug discovery
Wojciech Zawodny, Astex - 10:40
- Real world comparison of dynamic ultra large library screening with commercial library screening against different target classes
Jonathan Heal, RxCelerate - 11:20
- Chemical libraries space – a new library design paradigm
Alexandre Varnek, University of Strasbourg - 12:00
- Chemical space inspired design using the generated databases (GDBs)
Jean-Louis Reymond, University of Bern - 12:40
- Lunch and poster session
- 13:40
- Saturated benzene bioisosteres for medicinal chemistry
Pavel Mykhailiuk, Enamine (remote presentation) - 14:20
- The bRo5 chemical space as a source of new oral drugs: we can see the light at the end of the tunnel
Giulia Caron, University of Turin - 15:00
- New strategies for identification of weak acids at Syngenta
Alex Smith, Syngenta - 15:40
- Refreshment break
- 16:00
- On-demand continuous flow synthesis
Tim Jamison, MIT (remote presentation) - 16:45
- Discovery and development of MK-1454, a therapeutic cyclic dinucleotide sting agonist
Matthew Maddess, Merck - 17:30
- Close of conference
SCI’s Fine Chemicals Group are committed to promoting diversity and equality in the chemical sciences. We aim to identify high quality speakers for all our conferences with full inclusivity where attendees from all backgrounds are welcome. We are open to offering flexible presentation options.
Sponsorship Information
For further information and prices, please email conferences@soci.org.
Venue and Contact
SCI
14/15 Belgrave Square
London
SW1X 8PS
Conference Team
Tel: +44 (0)20 7598 1561
Email: conferences@soci.org
Fees
| Early bird - ends 11 Sept 2023 SCI Member - £90 Non-member - £120 Student Member - £45 |
| After early bird SCI Member - £140 Non-member - £170 Student Member - £70 |
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Booking Process/Deadlines
CPD Info
SCI Members attending this meeting are able to claim CPD points.
Exhibitors
Sponsors
Organising Committee
Helen Horsley, SCI / UCB
Martin Lowe, SCI / Exscientia
Antonio Misale, SCI / Janssen Pharmaceutical Companies of Johnson & Johnson
Nat Monck, SCI / Evotec
Jason Tierney, SCI / Medchemica / Top Tier Consultancy
