What effect do vaping and air pollution have on your heart, and how could a light-powered pacemaker improve cardiovascular health?
It seems that every day, scientists are learning more about the factors affecting cardiovascular health and are coming up with novel ways to keep our hearts ticking for longer. Here are three interesting recent developments.
One of the problems with existing pacemakers is that they are implanted into the heart with one or two points of connection (using screws or hooks). According to University of Arizona researchers, when these devices detect a dangerous irregularity they send an electrical shock through the whole heart to regulate its beat.
These researchers believe their battery-free, light-powered pacemaker could improve the quality of life of heart disease patients through the increased precision of their device.
The way existing pacemakers work can be quite painful for heart disease patients.
Their pacemaker comprises a petal-like structure made from a thin flexible film (that contains light sources) and a recording electrode. Like the petals of a flower closing up at night, this mesh pacemaker envelops the heart to provide many points of contact.
The device also uses optogenetics – a biological technique to control the activity of cells using light. The researchers say this helps to control the heart far more precisely and bypass pain receptors.
‘Right now, we have to shock the whole heart to do this, [but] these new devices can do much more precise targeting, making defibrillation both more effective and less painful,’ said Igor Efimov, professor of biomedical engineering and medicine at Northwestern University.
‘Current pacemakers record basically a simple threshold, and they will tell you,’ added Philipp Gutruf, lead researcher and biomedical engineering assistant professor. ‘This is going into arrhythmia, now shock, but this device has a computer on board where you can input different algorithms that allow you to pace in a more sophisticated way.’
Another potential benefit is that the light-powered device could negate the need for battery replacement, which is done every five to seven years. That use of light to affect the heart rather than electrical signals could also mean less interference with the device’s recording capabilities and a more complete picture of cardiac episodes.
The device uses light and a technique called optogenetics, which modifies cells that are sensitive to light, then uses light to affect the behavior of those cells. Image by Philipp Gutruff.
>> See how Bright SCIdea winner Cardiatec uses AI to improve heart disease treatment.
We don’t know a lot about the long-term effects of vaping because people simply haven’t been doing it long enough, but a recent study from the University of Wisconsin (UW) suggests that it could be bad for the heart.
Researchers selected a group of people who had used nicotine delivery devices for 4.1 years on average, those who smoked cigarettes for 23 years on average, and non-smokers and compared how their hearts behaved after smoking (the first two groups) and after exercise.
The researchers noticed differences minutes after the first two groups smoked or vaped. ‘Immediately after vaping or smoking, there were worrisome changes in blood pressure, heart rate, heart rate variability and blood vessel tone (constriction),’ said lead study author Matthew Tattersall, an assistant professor of medicine at the University of Wisconsin School of Medicine and Public Health.
The lack of long-term data means we still don’t know the effect of vaping.
Those who vaped also performed worse on the four exercise parameters compared to those who hadn’t used nicotine. Perhaps the most startling finding was the post-exercise response of those who had vaped for just four years compared to those who had smoked tobacco for 23 years.
‘The exercise performance of those who vaped was not significantly different from people who used combustible cigarettes, even though they had vaped for fewer years than the people who smoked and were much younger,’ said Christina Hughey, fellow in cardiovascular medicine at UW Health, the integrated health systems of the University of Wisconsin-Madison.
We know that smoking and passive-smoking are bad for our hearts, but some overlook the effect of other environmental toxins, especially those common to specific geographical regions.
A collaborative study including US and UK researchers has found a divergence in the types of environmental contaminants that contribute to cardiovascular ailments in both countries, aside from the prevalent smoking-related heart disease.
Hopefully, the growth in electric vehicle use will reduce air pollution
The study found that lead-related poisoning is more common in the US, whereas air pollution has a more damaging effect in the UK due mainly to increased population density. The researchers found that 6.5% of cardiovascular deaths were associated with exposure to particulate matter over the past 30 years compared to 5% in the US.
The one plus is that research has found that there has been a steady decline in cardiovascular deaths stemming from lead, smoking, secondhand smoke and air pollution over the past 30 years. Nevertheless, it will be of little comfort to those walking in the trail of exhaust fumes in cities.
‘More research on how environmental risk factors impact our daily lives is needed to help policymakers, public health experts, and communities see the big picture,’ said lead author Anoop Titus, a third-year internal medicine resident at St. Vincent Hospital in Worcester, Massachusetts.
Rarely have science and government been as clearly linked as the initial response to the Covid-19 pandemic, when politicians could be heard claiming they were being ‘led by the science’ as often as they could be seen doing that pointing-with-a-thumb-and-fist thing.
This Thursday, the UK’s Chief Scientific Adviser, Sir Patrick Vallance, will receive the Lister Medal for his leadership during the Covid-19 pandemic, and you can stream it live here, exclusively on SCI’s YouTube channel!
In readiness for Sir Patrick’s lecture, Eoin Redahan looks back at three ways science helped to mitigate the spread of Covid-19.
People will never look at vaccine development the same way. For good or ill, we have realised just how quickly they can now be developed. Similarly, we have realised what can be achieved when the brightest brains come together. These are two of the positive legacies from Covid.
But there are others. Some of the innovations conceived to tackle Covid will now tackle other pathogens. Here are just three of the innovations that emerged…
As Oscar Wilde once said: ‘We are all in the gutter, but some of us are looking up at the genetic material in stool samples.’
Not many people would find inspiration in wastewater treatment plants when thinking about early warning systems for infectious diseases.
Nevertheless, during the Covid-19 pandemic, researchers at TU Darmstadt in Germany came up with a system that detected Covid infection rates in the general population by analysing their waste – a system so accurate they could detect the presence of Covid among those without recognisable symptoms.
To do this, they examined the genetic material in samples from Frankfurt’s wastewater plants and tested them using the PCR test. They claim that their measurement was so sensitive it could detect fewer than 10 confirmed Covid-19 cases per 100,000 people.
It is inevitable that Covid-19 variants will rise again, but this system could alert us to the need for tighter protective measures as soon as the virus appears in our wastewater.
UV light can reportedly reduce indoor airborne microbes by 98%.
Warning systems are important, as are ways to stop the spread of pathogens. To do this, a team from the UK and US shed light on the problem – well, they used ultraviolet light to remove the pathogens.
Using funding from the UK Health Security Agency, Columbia University researchers discovered that far-UVC light from lights installed in the ceiling almost eliminate the indoor transmission of airborne diseases such as Covid-19 and influenza.
The researchers claim it took less than five minutes for their germicidal UV light to reduce indoor airborne microbe levels by more than 98% – and it does the job as long as the light remains switched on.
‘Far-UVC rapidly reduces the amount of active microbes in the indoor air to almost zero, making indoor air essentially as safe as outdoor air,’ said study co-author David Brenner, director of the Center for Radiological Research at Columbia University Vagelos College of Physicians and Surgeons. ‘Using this technology in locations where people gather together indoors could prevent the next potential pandemic.’
‘Physical mask, meet biological mask.’
Many moons ago, it was strange to see a person wearing a mask, even in cities with dubious air quality. Now, they are ubiquitous, and it would appear that mask innovations are everywhere too.
During Covid, researchers from the University of Granada in Spain were aware that wearing masks for a long time could be bad for our health. They devised a near field communication tag for inside our FFP2 masks to monitor CO2 rebreathing. This batteryless, opto-chemical sensor communicates with the wearer’s phone, telling them when CO2 levels are too high.
In the same spirit, researchers in Helsinki, Finland, developed a ‘biological mask’ to counteract Covid-19. The University of Helsinki researchers developed a nasal spray with molecule (TRiSb92) that deactivates the coronavirus spike protein and provides short-term protection against the virus – a sort of biological mask, albeit without those annoying elastics digging into our ears.
‘In animal models, nasally administered TriSb92 offered protection against infection in an exposure situation where all unprotected mice were infected,’ said Anna Mäkelä, postdoctoral researcher and study co-author.
‘Targeting this inhibitory effect of the TriSb92 molecule to a site of the coronavirus spike protein common to all variants of the virus makes it possible to effectively inhibit the ability of all known variants.’
The idea is for this nasal spray to complement vaccines, though during peak Covid paranoia, it might be tricky persuading everyone on the bus that you’re wearing a biological mask.
Covid disrupted scientific progress for many, but as we know, invention shines through in troublesome times. Plenty of innovations such as the ones above will make us better equipped to tackle air borne diseases – alongside the stewardship of leaders like Sir Patrick Vallance.
Watch Sir Patrick Vallance’s talk – Government, Science and Industry: from Covid to Climate – at 18:25 on 24 November
What does clean smell like? What if the fragrance you want to create is that of a sweet-smelling, yet poisonous, flower? In his Scientific Artistry of Fragrances SCITalk, Dr Ellwood led us by the nose.
When Dr Simon Ellwood spoke about creating a fragrance, it sounded like a musical composition or a painting. The flavourist, sitting before a palette of 1,500 fragrance ingredients. Each occupies a different note on the register: the top notes, the middle ones, and the bottom.
To the outsider, this seems impossibly vast and daunting. The Head of Health & Wellbeing Centre of Excellence – Fragrance and Active Beauty Division at Givaudan mentioned that Persil resolved to come up with ‘the smell of clean’ for its detergents in the late 1950s.
But what should clean smell like? Should it be the green, citrusy aromas of this laundry detergent, the smell of mint, or the antiseptic at the hospital?
To make choosing smells slightly less daunting for flavourists and perfumers, they are at least split into odour families such as citrus, floral, green, fruity, spicy, musky, and woody. Some of these ingredients are natural, some are inspired by nature, and others come from petrochemicals and synthetic materials.
The delicious-smelling musk deer.
One of the smells you may have sprayed on your person – one sibling in this odour family – has peculiar origins. The pleasant, powdery smell known as musk was originally extracted from the caudal gland of the male musk deer and from the civet cat.
But as the Colognoisseur website notes, as many as 50 musk deer would have to be killed to obtain one kilogramme of these nodules. Now, killing a load of deer and cats for a few bottles of perfume may not have seemed unethical several centuries ago, but it also wasn’t sustainable or cost-effective. It became clear that a synthetic musk was needed.
When the synthetic musk discovery came in 1888, it was a chance discovery. Albert Bauer had been looking to make explosives when a distinctive smell came instead, along with the scent of opportunity.
>> Read about the science behind your cosmetics
Dior recreated the woodland notes of Lily of the valley.
Dr Ellwood’s talk laid bare not only the vastness of everything we smell, but also the ingenuity of those who recreate these odours. In terms of breadth of smell, neroli oil – which is taken from the blossom of a bitter orange – has floral, citrus, fresh, and sweet odours, with notes of mint and caraway. Similarly, and yet dissimilarly, jasmine’s odour families are broken down into sweet, floral, fresh, and fruity, and – jarringly – intensely fecal.
The ingenuity of flavourists is exemplified by lily of the valley. The woodland, bell-shaped flowers are known for their evocative smell, but all parts of the plant are poisonous. Despite this, French company Dior synthetically recreated the lily of the valley smell in its Diorissimo perfume in 1956 using hydroxycitronellal, which is described by the Good Scents Company as having ‘a sweet floral odour with citrus and melon undertones’.
Cyanide smells like almonds, but you might not want to eat it.
Of course, as Dr Ellwood noted, synthetic flavours can only ever get so close to the real thing – an imperfect facsimile. However, the mere fact that chemists have recreated deer musk, lily of the valley, and the prized ambergris from sperm whales to create the fragrances we love is almost as extraordinary as the smells themselves.
‘Fragrance,’ he said, ‘will always be the confluence of the artistry of the perfumer and the chemist.
Register for our free upcoming SCI Talk on the Chemistry behind Beauty & Personal Care Products.
In the second part of our chat with Bright SCIdea finalist Team Eolic Wall, we found out how they prepared for their presentation and judges’ questions, and what’s next for their innovative wind turbine technology.
The road from Eureka moment to finished product is paved with peril. Team Eolic Wall’s idea for small, modular wind turbines that use magnetic levitation to harness more power than existing turbines could bring wind power generation into our very homes. But bringing a groundbreaking product to market is not just about mastering the science. It must make business sense too.
As with the other Bright SCIdea hopefuls, Team Eolic Wall received free training from SCI in the form of online tutorials from experienced professionals including modules on structuring a business, financial modelling, branding, and marketing.
After completing the training, Eolic Wall rose to meet the challenge. The team qualified for the Bright SCIdea final and, with it, the pivotal presentation in front of a live audience and panel of expert judges.
Many of us take it as a given that we speak to people at work in our native tongue. The nuances of communication – the cultural subtleties and oddities of the English language – aren’t a concern. But Team Eolic Wall had to present in their second language.
‘This was not our first international presentation, but it was the first one in a foreign language,’ said Alfredo Calle, Eolic Wall founder, ‘so that's always a little bit intimidating until one gets used to it.’
The key to them nailing the pitch was in the spade-work. Calle and his colleagues rehearsed the speech until they knew it by heart. ‘It’s all about training and preparation,’ he said. ‘The more you rehearse, the more confident you feel when the presentation moment comes.’
Of course, the presentation is predictable but the judges’ questions are less so. Having undergone the rigours of competition, Calle recommends that this year’s entrants prepare by trying to predict the types of questions they will be asked. A cold rehearsal could help with the potentially stunning situation of someone throwing questions at you from strange angles.
That team Eolic Wall presented its technology online made theirs even trickier still, especially given a technical hitch at the beginning. But they had polished the presentation to a smoothness that offset such difficulties and came away as joint winners of the Audience Award.
The only lingering regret for them was that Covid prevented them from coming to London. ‘We wish we could have made it to the final,’ he said. ‘Facing the judges and audience live would have been a tremendously valuable and enriching experience.’
Since the Bright SCIdea final, the Eolic Wall is being built brick by brick. The team has received three grants in recent months including one from ProCiencia, the largest innovation agency of the Peruvian government.
Eolic Wall's wall-mounted wind turbine is designed to power homes and offices in situ.
However, perhaps the most exciting development is the technology itself. ‘We have accomplished a peripherally supported wind turbine that works with magnetic levitation,’ Calle said. ‘That's a huge milestone that makes us believe we are building something big.’
Calle hopes for more investment to develop the technology further. At heart, he believes the Eolic Wall will give regular people the chance to generate affordable wind energy from home.
‘We are working out a solution to democratise wind energy for the sake of this blue rock we call home.’
>> Find out how Team Eolic Wall’s innovative technology in part 1 of this blog.
Do you know how the Academy Awards came to be named the Oscars? What about the story behind the Nobel prize? Behind every award name there is a story, and the Julia Levy Award is no exception.
On the face of it, the Julia Levy Award is about innovation in biomedical applications, but it is the stories of the winners of this SCI Canada award, and Julia Levy herself, that really give it life.
But for a tweak of history, Julia Levy may not have ended up in Canada at all. Born Julia Coppens in Singapore in 1934, she moved to Indonesia in her early childhood. Her father uprooted the family during the Second World War and she left for Vancouver with her mother and sister – her father only joining them after release from a Japanese prisoner-of-war camp.
Julia and her family moved to Vancouver during the Second World War.
After studying bacteriology and immunology at the University of British Columbia (UBC), the young Julia received a PhD in experimental pathology from the University of London. She went on to become a professor at UBC and helped found biopharmaceutical company Quadra Logic Technologies in 1984.
More important than confining her achievements in cold prose, Julia Levy’s work made a profound difference to people’s lives. She developed a groundbreaking photodynamic therapy (PDT) that treated age-related macular degeneration – one of the leading causes of blindness in the elderly. She also created a bladder cancer drug called Photofrin in 1993 and, according to Neil and Susan Bressler, the Visudyne PDT treatment created by Julia and her colleagues was the only proven treatment for certain lesions.
Levy thrived in the business space too, serving as Chief Executive Officer and President of QLT from 1995 to 2001. She has since won a boatload of awards for her achievements, but sometimes the best testimonies come from those who have been inspired by her achievements.
For Helen Burt, winner of the 2022 Julia Levy Award and retired Angiotech Professor of Drug Delivery at the University of British Columbia (UBC), Julia has been an inspiration. Here was this UBC professor who jointly founded this big, exciting company – creating medication that improved people’s lives and showing her what was possible.
Helen, an English native, moved to Vancouver in 1976 for her PhD and loved it so much that she stayed. As a professor at UBC, Helen would become a trailblazer in drug delivery systems – a field pioneered earlier by Julia Levy.
‘I was a new assistant professor when she was building Quadra Logic and I would go to talks that she gave,’ Helen said. ‘Essentially, the early technology for QLT was a form of very sophisticated drug delivery [...] It was getting the drug they developed into the eye and irradiating it with light of a specific wavelength.
‘It was very, very targeted. And so, you didn’t get the drug going elsewhere in the body and causing unwanted side effects. So her technology was a form of very advanced drug delivery technology.’
‘For me to win an award that honours Julia Levy and her achievements – I think that's what makes it so special to me.’ – Professor Helen Burt, a former student of Julia Levy, is the Award's most recent recipient.
>> Learn more about SCI Canada.
These talks chimed with the young Helen. If a microbiologist could develop this kind of technology, what was stopping her from developing her own?
She, too, became a pioneer in her field, developing nanoparticle-based drug delivery systems (including those to treat cancer) and a novel drug-eluting coronary stent. According to Professor Laurel Schafer, who put Helen forward for the Julia Levy Award: ‘[Helen] was a trailblazer in new approaches for drug delivery and in research leadership on our campus.’
Professor Schafer is a hugely accomplished chemist in her own right; and the University of British Columbia chemistry professor’s achievements in catalysis discovery were recognised with the LeSueur Memorial Award at the 2020 Canada Awards.
Julia Levy provided an inspiration to Laurel too, in her case as an exemplar for what Canadian chemists could achieve. ‘The achievements of Julia Levy show that it really can be done right here in Canada, and even right here in British Columbia,’ she said. ‘I grew up in a Canada where I believed that better was elsewhere and our job was to attract better here – a very colonial attitude.
Julia studied at and later became a Professor at the University of British Columbia – the campus is pictured above.
‘I now believe and know that better is right here. Professor Levy’s work showed that world-leading contributions come from UBC and from the laboratories led by women.’
She noted that the Julia Levy Award acknowledges Canadian innovation in health science, whereas Canadian chemistry has historically focused on process chemistry in areas such as mining and petrochemicals.
But Julia Levy’s influence permeates beyond science. ‘Julia is one of those people who has been willing throughout her whole career – even now, well into her eighties – to give back to the community,’ Professor Burt says. ‘She mentors, she coaches, she sits on the boards of startup companies, and she advises.’
‘She’s just got this incredible amount of knowledge… She was the Chief Executive Officer [at QLT], so she learnt all of the aspects: the complex and sophisticated regulations, knowing how to find the right people to conduct clinical trials, and how to do the scale-up. She really is a legend in terms of giving back to the community. And this is not just in British Columbia – it’s Pan-Canadian.’
Pictured above: Julia Levy
For young chemists, the Julia Levy in the Julia Levy Award may just be a name for now, but for those in the Canadian chemical industry and patients all over the world, her influence and her work resonate.
As Professor Helen Burt said: ‘For me to win an award that honours Julia Levy and her achievements – I think that's what makes it so special to me.’
>> For more information on the Canada Awards, go to: https://bit.ly/3VMwNKa
Imagine owning a small wind turbine that generates all of your home’s energy needs. As the clock counts down on entries for for the 2023 Bright SCIdea Challenge, we caught up with Team Eolic Wall, the Audience Winner for the 2022 competition.
Eolic Wall was always a nice fit for Bright SCIdea. The team spotted a problem in our renewable energy mix and came up with a scientific business idea to solve it. They saw that wind energy is generated for the public, but it isn’t generated by the public. This stands in bright contrast to solar power generation.
‘Today, 40% of all installed capacity in solar energy is based on solar panels installed on the rooftops of home and corporate buildings,’ said Alfredo Calle, founder of Eolic Wall. ‘The remaining 60% correspond to solar farms.’
Eolic Wall's wall-mounted wind turbine is designed to power homes and offices in situ.
The wind industry is different. ‘Only 1% of the installed capacity comes from households and businesses,’ he added. ‘That is, 99% of all installed capacity in the world comes from wind farms. That sort of concentration is a problem that hampers the energy transition.’
Calle believes this disparity hampers the move from fossil fuel dependency to clean, renewable energy. For many, micro-generation is key. We need to put power – renewable power – in the hands of the people. His idea is to make wind energy available in the home, just as solar exists on roofs everywhere.
The scale of this task is daunting. It turns out there’s a reason why we don’t all have wind turbines bolted onto our homes. The problem, Calle argues, is that a windmill must be large to be efficient.
He believes the Eolic Wall could change that – that this wall-mounted wind turbine is efficient enough to power our homes and offices.
‘We have created a technology that not only doubles wind speed to harvest more power from the same wind resources, but also has a wind turbine that works with magnetic levitation to almost eliminate any friction.’
So, how did a team based out of the National University of Engineering in Peru and Universidade Estadual Paulista in Brazil end up competing for the £5,000 first prize in the Bright SCIdea final?
Chance. Fortune. Happenstance. Calle and his colleagues came upon Bright SCIdea through a social media post that immediately captured their attention.
‘We thought that the Eolic Wall was ideal for Bright SCIdea because of the huge positive impact that this technology could have,’ he said, ‘and also because it perfectly fit into Bright SCIdea’s thesis of supporting ideas in the intersection of business, innovation and science.’
Applying was simple, although the business plan submission was intimidating at first. However, like all BrightSCIdea applicants they received coaching, and their brainchild found form.
‘The key driver to overcome that challenge was not to miss any training sessions and tutorials,’ Calle said. ‘The good news is that after going through the whole process you feel that everything was worthwhile. No pain, no gain.’
Check out fellow 2022 finalist Klara Hatinova from Team Happy BioPatch in conversation with the Periodic Fable podcast.
Little machines that blend makeup tailored for your skin alone… Technology that details the tiny creatures walking on your face… The cosmetic revolution is coming, and Dr Barbara Brockway told us all about it.
Max Huber burnt his face. The lab experiment left him scarred, and he couldn’t find a way to heal it. So, he turned to the sea. Inspired by the regenerative powers of seaweed, he conducted experiment after experiment – 6,000 in all – until he created his miracle broth in 1965. You might know this moisturiser as Crème de la Mer.
A rocket scientist in the world of cosmetics seems strange, but when you interrogate it, it isn’t strange at all. As Dr Barbara Brockway, a scientific advisor in cosmetics and personal care, explained in our latest SCItalk, cosmetics hang from the many branches of science.
Engineering, computer science, maths, biology, chemistry, statistics, artificial intelligence, and bioinformatics are among the disciplines that create the creams you knead into your face, the sprays that stun your hair in place. They say it takes a village to raise a child, and it takes an army of scientists to formulate all the creams, gels, lotions, body milks, and sprays in your cupboard.
Some say sea kelp can be used to treat everything from diabetes, cardiovascular diseases, and cancer, to repairing your nails and skin.
There is a reason why the chemistry behind these products is so advanced. If you sell bread, it is made to last a week. If you make a moisturising cream, it is formulated to last three years. To make sure it does that, chemists test it at elevated temperatures to speed up the time frame. They conduct vibration tests and freeze-thaw tests to measure its stability.
Dr Brockway likened the process of bringing a product to market to a game of snakes and ladders. If you climb enough ladders, you could take your own miracle brew to market within 10 months.
But expectations are high, and the product must delight the user. Think of the teenager who empties a half a can of Lynx Africa into his armpit, or the perfume that is a dream inhaled. Each smell she likened to a musical composition.
But these formulators are not struggling artists. Perfumers and cosmetic chemists – these bottlers of love and longing and loss – can earn a fortune. Dr Brockway’s quick calculation provided a glimpse of the lucre.
Take 15kg of the bulk cream you mixed on your kitchen table. That same cream could be turned into 1,000 15ml bottles, each sold for £78. So, just 15kg of product could fetch £78,000. So, it’s easy to see why the global beauty market is worth $483 billion (£427 billion), with the UK market alone worth £7.8 billion – more than the furniture industry.
It’s unsurprising that an industry of such value and scientific breadth embraces the latest technologies, from those found in our phones to advances in genetics and the omics revolution.
Already, the digital world has left the makeup tester behind. Smart mirrors overlay virtual makeup, recommend products for your complexion, and even detect skin conditions. Small machines that look like coffee-makes blend bespoke makeup. Indeed, Dr Brockway noted that Yves Saint Laurent has created a blender that produces up to 15,000 different shades.
Even blockchain has elbowed into the act. It is being used to make sure that a product’s ingredients aren’t changed in between batches. By showing customers every time-stamped link of the supply chain, companies can prove that their products are organic or ethically sourced. The reason why blockchain is significant here is that, once recorded, the data stored cannot be amended.
At first glance, proving the provenance of materials to customers might seem like a marketing ploy, but this is also being done in response to the increasing fussiness of the consumer.
Collagen is the main component of connective tissue.
Dr Brockway said all brands are now under pressure to incorporate sustainability into their business practices. The younger age group is also looking for more organic, vegan-friendly ingredients, and businesses have had to respond.
For example, microbial fermentation is being used instead of roosters’ coxcombs to create hyaluronic acid. Similarly, Geltor claims to have created the first ever biodesigned vegan human collagen for skincare (HumaColl21®). Such collagen is usually provided by our friends the fish.
These advances are significant, certainly to the life expectancies of roosters and fish, but of such ingredients revolutions are not made. Other forces will shake the industry.
Back in the 1970s, scientists thought the microbes that live on our skin were simple, but next-generation DNA technology reveals that thousands of species of bacteria live on our skin (a pleasant thought). Dr Brockway says these microbes tell us about our lifestyles – to the point that they even know if you own a pet.
So, what is the significance of this? Developments in DNA technology and omics (various disciplines in biology including genomics, proteomics, metagenomics, and metabolomics) mean we can now get not just a snapshot, but an entire picture of what’s going on on your face.
‘Thanks to omics we really know what’s now going on with our skin and see what our products are doing,’ Dr Brockway said. ‘We know the target better. We know which collagens, out of the 263, we need to encourage.’
We are learning more and more about how our skin behaves. And those time-honoured potions and lotions espoused by our grandparents – it will make sense soon, not just why they work, but why they work for some and not for others. In cosmetics, we are leaving the era of checkers and entering the age of chess.
This is the first of three cosmetic SCItalks between now and Christmas. Register now for the Scientific artistry of fragrances.
Reading outside his research area and efficient chemistry helped 2022 Perkin Medal winner Dennis Liotta develop groundbreaking drugs.
There has been an explosion of statistics in football, but one of the most influential figures in this revolution, Ramm Mylvaganam, didn’t care for the game. He worked for the confectionary company Mars. He sold chairs. He knew nothing about football.
However, this key figure outlined in Rory Smith’s recent book, Expected Goals: The story of how data conquered football, came into the field of football analysis and changed the game forever – partly because he approached the game with the fresh perspective of the outsider.
So, what do football statistics have to do with a chemist who came up with life-saving medications? Well, Dr Dennis Liotta, who came up with AIDS antivirals that have saved thousands of lives, may not have entered medicinal chemistry as a complete outsider. He was a chemist, after all. However, like Ramm Mylvaganam, his broad breadth of knowledge from different areas gave him a unique perspective on a new field.
Dr Liotta didn’t take the standard path into medicinal chemistry. In fact, he wasn't a diligent chemistry student at first – and that, in an odd way, contributed to his later success.
For the first couple of years at university, he was more interested in his extracurricular activities; but in his third year, he realised he needed to catch up. He worked hard and burnt the midnight oil. He also did something unusual.
‘I did something that’s kind of ridiculous-sounding,’ he said. ‘I had this big fat organic chemistry book, and I would just open it up randomly to some page and read 10 or 12 pages and close it back up. Over time, I ended up covering not only the things I missed, but actually learning about a lot of things that wouldn't have been covered.’
As his career progressed, Dr Liotta realised the importance of not just working harder, but working smarter. On Sundays, he would sit down with a bunch of academic journals to stay abreast of developments. However, as he read them, he discovered other papers – ones outside his research area – that piqued his interest.
Dennis Liotta in one of his lab spaces at Emory. Image by Marcusrpolo.
‘I’d see something intriguing. And so I’d say, that’s interesting, let me read. I started learning about things that I didn’t technically need to know about, because they were outside of my immediate interest. But those things really changed my life. And, ultimately, I think they were the differentiating factor.’
This intellectual curiosity led to more than 100 patents, including a groundbreaking drug in the fight against AIDS that is still used today and a hand in developing an important hepatitis C drug.
‘In science, many times the people who actually make the most significant innovations are the people who come at a problem that’s outside of their field,’ Dr Liotta said. ‘Without realising it, we all get programmed in terms of how we think about problems, what we accept as fact.’
‘But when you come at a problem that’s outside your field… you aren't immersed in it. So, you think about the problems differently. And many times, in thinking about the problems differently, you’ll come up with an alternative solution that people in the field wouldn’t.’
We’ve often heard the stories of Steve Jobs wandering into random classes while at university when he should have been attending his actual course. Apparently, a calligraphy class inspired the font later used in Apple’s products. In other words, early specialism can sometimes hinder creativity.
‘I've looked into people who have made really some amazing contributions, and many times there’s been an intellectual stretch,’ Dr Liotta said. ‘They’ve gone out there and done something that they weren’t really trained to do. You can fall on your face from time to time, but it’s really nice when we're able to make contributions in areas where we don’t really have any formal training.’
Of course, there’s so much more to creating life-saving drugs than intellectual curiosity and a different way of thinking. Dr Liotta and his colleagues had the technical skill to turn their ideas into something real. He was a skilled chemist who teamed up with an excellent virologist, Raymond Schinazi. The result of this blend of their skills gave them an edge over others developing AIDS therapeutics.
Dr Liotta invented breakthrough HIV drug Emtricitabine.
‘The very first thing we did was we figured out a spectacular way of preparing the compounds – very clean, very efficient,’ he said. ‘And that [meant we could] explore all sorts of different permutations around the series of compounds that others couldn’t easily do, because their methods were so bad for making [them].
‘So, even though we were competing against some very important pharmaceutical companies that had infinitely more money than we had – dozens of really smart people they put on the project – we were able to run circles around them because we had a really efficient methodology and that enabled us to make some compounds.’
The amazing thing is that the very first compound and the third compound the pair came up with led to FDA-approved drugs. It is a fine thing, indeed, when skill and serendipity meet.
‘Chance favours the prepared mind,’ Dr Liotta said, ‘or, as my colleagues say: you work hard to put yourself in a position to get lucky.’
>> Learn more about Dr Liotta’s career path and research from our recent Q&A.
From luminescent polymer nanoparticles that improve rural healthcare to compostable plastic packaging, Dr Zachary Hudson and his research group at the University of British Columbia are developing solutions to pressing issues.
For those of us who live in cities, we take easy access to hospitals for granted, but what about those in remote areas? What if there were an easier way to diagnose diseases and improve healthcare for those in secluded rural areas?
Luminescent dyes used to make fluorescent Pdots.
Well, Dr Zachary Hudson and his group at the University of British Columbia (UBC) in Canada are developing luminescent polymer nanoparticles that could provide portable, low-cost tools for bio-imaging and analysis in rural areas. These nanoparticles are so bright that they can be detected by smartphone, helping clinicians quantify chemical substances of interest such as cancer cells.
Dr Hudson’s work spans other areas too, including working with industry to develop compostable plastics and ongoing research in opto-electronics. His creativity in applied polymer science was recognised recently with the 8th Polymer International-IUPAC award, organised by SCI, the Editorial Board of Polymer International, and IUPAC (International Union of Pure and Applied Chemistry).
We caught up with Zac to ask about these luminous Pdots, compostable plastics, and how it felt to be recognised by his peers.
Dr Zachary Hudson
Tell us about the nanoparticle and remote diagnostic technologies you are developing to boost rural healthcare.
Our group is working with Professor Russ Algar, an analytical chemist at UBC, to develop fluorescent nanoparticles that are bright enough to be detected by a handheld smartphone camera.
The concept is to design nanoparticles that can quantify biological analytes of interest, such as cancer cells or enzymes, and provide a signal that a smartphone can measure. In this way, we hope to create portable, low-cost tools for bioanalysis for use in remote or low-income regions.
Why is the capacity to conduct remote diagnostics so important for those in remote areas?
Coming from Vancouver, I have ready access to sophisticated lab facilities and hospitals that are only a short distance from where I live. This gives me access to some of the world’s most advanced techniques in molecular medicine with relative ease.
For most of the world’s population, however, geography or resources limit their access to these advanced tools that can have a real, positive impact on human health. Expanding access to molecular diagnostic technologies can help more people get the diagnosis they need without a dedicated lab.
How did the ideas for the Pdots come about?
We became interested in Pdots due to Professor Algar’s groundbreaking work using quantum dots for smartphone-based bioanalysis. We learned that by tapping into the versatility of polymer chemistry, we could create polymer nanoparticles, or Pdots, that combined many advanced functions into a single particle.
>> From Covid-19 to the two World Wars, how has adversity shaped innovation? We took a closer look.
How have you worked with other partners to turn these ideas into a reality?
We are currently planning a major initiative with rural health organisations in British Columbia to help move these tools toward practical use. Stay tuned for more info!
You’ve also worked with local industry to reduce the use of single-use plastics. How have you gone about this?
There has been a major push in Canada to reduce the consumption of single-use plastics, and many companies are currently developing new products to respond to this need. Our lab has worked with local industry to formulate and test compostable plastics that can act as substitutes for petroleum-based plastics in consumer packaging.
The Nexe Pod, a fully compostable, plant-based coffee pod created by NEXE Innovations, with Zac as Chief Scientific Officer, received a $1m funding grant from the Canadian government in 2021.
You’ve helped develop compostable materials. How tricky is this from both a material and an environmental perspective?
Compostable plastics are challenging for a few reasons: the demand for them is skyrocketing, so robust supply chains are needed to help companies get away from petroleum feedstocks. The regulatory framework around compostable plastics also varies widely by country, which poses challenges for international commercialisation.
Finally, most machinery for the high-speed manufacturing of plastic packaging is highly optimised for petroleum-based plastics, so new equipment and techniques that are suitable for processing compostable plastics need to be developed alongside the plastics themselves.
>> Do you work in pharmaceutical development? Check out our upcoming events.
What’s next for these innovations, and are you working on anything else interesting?
I've spent most of my career working on light-emitting materials for display technologies and bioimaging, and we’ve recently learned that many of these same materials make useful photocatalysts with applications in the pharmaceutical industry.
We recently partnered with Bristol Myers Squibb to develop all-organic photocatalysts with performance on par with some of the expensive iridium-based catalysts that industry is currently using. I'm looking forward to developing this area further.
What was it like to win the 8th Polymer International-IUPAC award for Creativity in Applied Polymer Science?
It was a great feeling to have our group’s work recognised by the international polymer community. The award lecture at the IUPAC conference also gave us the perfect venue to highlight some of the research directions I’m most excited about in the years ahead.
Have we underestimated the eco-anxiety middle-aged and older people feel? According to a recent survey, younger folks aren’t the only ones frowning at the horizon. Eoin Redahan writes.
When you think of a middle-aged person suffering from exo-anxiety, what do you imagine? Is it a grey-haired woman gazing from a mountain peak with a single, heroic tear staining her cheek? Is it an auld fella rending his garments and shaking his fist at the sun?
I mean, possibly, but the reality is probably less dramatic. It could be the Pakistani householder who wonders if her family home will be swept away in the next flood. It might be the 39-year-old Australian who wonders if his country will be habitable when his young child grows up.
It might be the Maldivian who wonders if his homeland will go the way of Atlantis within 20 years. It was me when someone decided it would be a good idea to have a barbecue in the fields beside my house in the middle of the heatwave – when the grass was as dry as straw and wildfires scorched in south London.
Athanasius Kircher's map of Atlantis, placing it in the middle of the Atlantic Ocean, from Mundus Subterraneus, 1669. Will people pore over maps of the Maldives in the same way?
The presumption by many is that it’s only the young who feel anxious about climate change, for it is they who will inherit the mess. However, according to recent ONS statistics, the middle-aged and the old are almost as worry-weary as young people.
Having analysed a recent ONS Opinions and Lifestyle Survey, straw specialist firm Drinking Straw filtered some of the stats. They reveal that 62% of UK people over the age of 16 worry that rising temperatures will directly affect them by 2030. Of these, 70% of 16-29 year olds were worried about the heat, but 59% of 50-69 year olds were also worried, as were 57% of those aged 70 and over.
In other areas, the differences were even less stark. When it came to anxiety over extreme weather events, 48% of all adults were worried – only slightly less than the 49% of 16 to 29 year olds who did so.
>> How can I make my garden more sustainable? Professor Geoff Dixon shows us how.
Similarly, regarding water supply shortages, 40% of all adults are concerned about them overall, compared to 43% of those aged 16 to 29. Admittedly, young people are more worried than older adults about rising sea levels (45% vs. 31%), but the differences are noticeably narrow in most metrics.
Surprisingly, it turns out the percentage of those who don’t care at all about the merciless heat, parched land, rising sea levels, and freak weather events is fairly consistent across all segments, with the 12% of 16-29 year olds not giving a fig similar to the 14% of indifferent adults.
ONS figures reveal that most people have made climate-friendly changes to their day-to-day lives, whether they grew up in the age of renewables or the age of coal.
Broadly speaking, UK adults are becoming more eco-conscious, if data from the ONS’ Climate change insights, families and households, UK: August 2022 survey are to be believed. The survey has found that 77% of adults have made some, or a lot of changes, to their lifestyles to tackle climate change.
When the remaining 23% were asked why they made no change to their lifestyles, the most common reason given was: the belief that large polluters should make changes before individuals, followed closely by those who felt that individual change wouldn’t make much of a difference.
It’s clear to most of us that the government must help drive change, including on our roads. Despite the UK’s lagging electric vehicle infrastructure, the study revealed that the number of licensed zero emission vehicles, ultra-low emission vehicles, and plug-in vehicles increased by 71% or more last year.
If people knew there were sufficient charging points dotted around their areas – and if they were further incentivised to give up their gas-guzzling vehicles – those numbers would surely increase.
As bleak as the situation is, it is heartening to see our attitudes changing. Now, if you’ll excuse me, I’ve just read a climate-related story that brought a tear to my eye. If anyone wants me, I’ll be weeping in a dark room (passive-cooled, mercifully).
Those with the blood group O reportedly have the lowest likelihood of catching Covid-19, and the new top-up jab should provide relief against sub-variants of the disease.
By now, most of us have been stricken by Covid, but 15% of people in the UK have evaded the virus. According to a testing expert at the London Medical Laboratory, the great escape is down to three factors: blood group, vaccines, and lifestyle.
Having assessed the findings of recent Covid-19 blood type studies, Dr Quinton Fivelman PhD, Chief Scientific Officer at London Medical Laboratory (LML), believes that people with the blood group O are less likely to be infected than those with other blood groups, while those with blood type A are far more likely to contract the virus.
‘There have now been too many studies to ignore which reveal that people have a lower chance of catching the virus, or developing a severe illness, if they have blood group O,’ he said.
Indeed, research from the New England Journal of Medicine had previously found that those with blood type O were 35% less likely to be infected, whereas those with Type A were 45% more vulnerable. A further benefit of type O blood is the reduced risk of heart disease compared to those with type A or B blood.
>> What is the ideal body position to adopt when taking a pill? Wonder no more.
Staged stock images are not thought to increase your chances of contracting Covid-19.
According to the NHS, almost half of the population (48%) has the O blood group; so, clearly, other factors come into play in terms of our susceptibility. Dr Fivelman said: ‘By far the most important factor is the number of antibodies you carry, from inoculations and previous infections, together with your level of overall health and fitness.’
So, those who are more careful about visiting crowded places, who eat well, and are fortunate enough not to have an underlying illness have better chances of avoiding Covid-19. According to LML, having been vaccinated also helps, though these benefits have slowly worn off. That is why the new top-up jab with the Omicron variant could provide some relief for those who take it.
‘The new Omicron jab has come none-too-soon, so many people are now suffering repeated Covid infections,’ he added. ‘That’s because the new Omicron BA.4 and BA.5 sub-variants do not produce as high an immune response as the previous strains, so re-infection is more likely to occur.
‘Higher levels of antibodies are important to neutralise the virus, stopping infection and limiting people transmitting the virus to others.’
>> Which herbs could boost your wellbeing? Dr Vivien Rolfe tells us more.
What is the best posture to adopt when taking a pill, and why does it help your body to absorb the medicine quicker?
Was Mary Poppins wrong? A spoonful of sugar may help the medicine go down, but does it do so in the most delightful way? Not according to Johns Hopkins University researchers in the US.
They say the body posture you adopt when taking a pill affects how quickly your body absorbs the medicine by up to an hour. It’s all down to the positioning of the stomach relative to where the pill enters it.
The team identified this after creating StomachSim – a model that simulates drug dissolution mechanics in the stomach. The model works by blending physics and biomechanics to mimic what’s going on when our stomachs digest medicine and food.
Looks like we’ve got a pro here.
Without further ado, here are the four contenders for taking the pill: standing up, lying down on your right side, lying down on your left side, and swallowing the pill on your back.
>> What’s next in wearables? We looked at a few Bright SCIdeas.
According to the researchers, if you take a pill while lying on your left side, it could take more than 100 minutes for the medicine to dissolve. Lying on your back is next in third, the narrowest of whiskers behind swallowing a pill standing up. This time-honoured method takes about 23 minutes to take effect.
However, by far the most effective method (and, therefore, the most delightful way) is lying on your right side, with dissolution taking a mere 10 minutes. The reason is that it sends pills into the deepest part of the stomach, making it 2.3 times faster to dissolve than the upright posture you’re probably taking to swallow your multi-vits.
Your posture is key in ensuring your body absorbs medicine quickly. Image: Khamar Hopkins/John Hopkins University.
‘We were very surprised that posture had such an immense effect on the dissolution rate of a pill,’ said senior author Rajat Mittal, a Johns Hopkins engineer. ‘I never thought about whether I was doing it right or wrong but now I’ll definitely think about it every time I take a pill.’
Next week, we will investigate more of the medical approaches espoused by much-loved fictional characters, starting with George’s Marvellous Medicine, before moving onto the witches in Macbeth. No one is safe.
In the meantime, you can read the researchers’ work in Physics of Fluids.
The Commonwealth Games has landed in Birmingham. Before the Games began, viewers were treated to an extraordinary opening ceremony (featuring a giant mechanical bull) and its artistic director, Iqbal Khan, was lauded for his ingenuity.
But such ingenuity shouldn’t surprise any of us, for Birmingham has long been a place of outsized invention. For more than 300 years, the inhabitants of this industrial powerhouse have churned out invention after invention; and its great pragmatists have turned patents into products.
Chemistry, too, owes a debt to the UK’s second city. Whether it’s the first synthesis of vitamin C, the invention of human-made plastic, adventures in mass spectrometry, or electroplated gold and silver trinkets, Birmingham has left a lasting legacy.
Here are five chemists whose innovations may have made an appearance in your life.
Plaque commemorating Alexander Parkes in Birmingham, England. Image by Oosoom
Look around you. Look at the computer screen, the mouse button you click, and the wire casings everywhere. Someone started it all. That man was Alexander Parkes, inventor of the first human-made plastic.
The son of a brass lock manufacturer from Suffolk Street, Birmingham, Parkes created 66 patents in his lifetime including a process for electroplating delicate works of art. However, none were as influential as the 1856 patent for Parkesine – the world’s first thermoplastic.
Parkes’ celluloid was based on nitrocellulose that had been treated by different solvents. In 1866, he set up the Parkesine Company at Hackney Wick, London, but it floundered due to high cost and quality issues. The spoils of his genius would be enjoyed by the rest of us instead.
Sir Norman Haworth
Sir Norman Haworth may have been born in Chorley, Lancashire, but his finest work arguably came after he became Director of the Department of Chemistry in the University of Birmingham in 1925. Haworth is famous for his groundbreaking carbohydrate investigations and for being the first to synthesise vitamin C.
By 1928, Haworth had confirmed the structures of maltose, cellobiose, lactose, and the glucoside ring structure of normal sugars, among other structures. Apparently, his method for determining the chain length in methylated polysaccharides also helped confirm the basic features of starch, cellulose, and glycogen molecules.
However, Haworth is most famous for determining the structure of vitamin C and for becoming the first to synthesise it in 1932. The synthesis of what he called ascorbic acid made the commercial production of vitamin C far cheaper – the benefits of which have been felt by millions of us.
For his achievements in carbohydrates and vitamin C, Haworth received the Nobel Prize for Chemistry in 1937 (shared with Paul Karrer). He was the first British organic chemist from the UK to receive this honour. Haworth even had a link to SCI, having been a pupil of William Henry Perkin Junior in the University of Manchester’s Chemistry Department.
Blue plaque for Francis William Aston. Image from Tony Hisgett
Another Nobel Prize-winning chemist from Birmingham is Francis William Aston. The Harborne native won the 1922 prize for discovering isotopes in many non-radioactive elements (using his mass spectrograph) and for enunciating the whole number rule.
For a time, academia almost lost Aston, as he spent three years working as a chemist for a brewery. Thankfully, he returned to academic life and obtained concrete evidence for the existence of two isotopes of the inert gas neon before the first World War.
After working for the Royal Aircraft Establishment during the Great War (1914-18), he resumed his studies. The invention of the mass spectrograph proved pivotal to his discoveries thereafter. Using this apparatus, he identified 212 naturally occurring isotopes.
George Elkington patented the electroplating process developed by John Wright. Image from Spudgun67
It isn’t surprising that George Elkington should become an SCI favourite, as he blended both scientific ingenuity with business. The son of a spectacle manufacturer patented the first commercial electroplating process invented by Brummie surgeon John Wright in 1840.
Wright discovered that a solution of silver in potassium cyanide was useful for electroplating metals. Elkington and his cousin Henry purchased and patented Wright’s process before using it to improve gold and silver plating.
The Elkingtons opened an electroplating works in the city’s now famous Jewellery Quarter where they electroplated cutlery and jewellery. And they didn’t do too badly out of it. By 1880, the company employed 1,000 people in seven factories.
1906 advertisement for Birds Custard powder. Image from janwillemsen
In 1837, Alfred Bird was in a pickle. He wanted to serve his dinner party guests custard, but his wife was allergic to eggs and yeast, and egg was the main thickening agent of this delicious gloop.
Instead of serving something else, the chemist shop owner invented his own egg-free custard by substituting cornflour for eggs. His guests found it delicious and Bird’s Custard was born.
Not content with this innovation, Bird is also credited with being the father of modern baking powder. Once again, his wife’s allergies were said to be the inspiration, as he wanted to create a yeast-free bread for her. In bread and custard, true love always finds a way.
Paulina Quintanilla has developed a clever way to maximise the froth flotation technology used to extract more valuable minerals from rocks. The SCI Scholar and Poster Competition winner chatted to us about her process and how it could make mineral processing more efficient.
How would you describe your froth flotation technology in simple terms?
Froth flotation is the most widely used technology to separate valuable mineral particles from waste rock. The process is carried out in stirred tanks in which chemical reagents and air are added. Some of these reagents, called collectors, make the valuable mineral particles hydrophobic, which means that they repel water.
Consequently, the valuable mineral particles attach to the air bubbles, covering them and generating bubble-particle aggregates. The bubble-particle aggregates rise to the top of the tank, forming a froth that overflows as a mineral-rich concentrate, while the waste rock leaves from the bottom of the tank as tailings.
Froth flotation is also relevant in several other industrial applications, such as water treatment and paper de-inking.
Schematic of the froth flotation process. Image by @AMPRG_Imperial.
How would you describe your froth flotation technology in simple terms?
This research focuses on optimising the froth flotation process using a control strategy called model predictive control. To this end, mathematical models were developed to represent the phenomena inside a flotation tank. These models are then used to ‘predict the future’ so that decisions can be taken now (we can control the process) to improve the froth flotation performance.
Model predictive control is a powerful optimisation strategy that has been widely used in other processes, including in the petrochemical industry, but it is still very new in the mineral processing industry.
One of the main advantages of this research is that the models are physics-based. This means that they were developed from the fundamental physics of the process rather than from data, which makes them useful under any operating conditions, for any flotation tank size. This is particularly interesting for application in the large flotation tanks used on an industrial scale.
How could this work benefit industry and make processing more efficient?
Building clean technologies for the transition to 100% green energy is creating a massive demand for a range of minerals. For example, copper mines would have to ramp up production considerably to satisfy the extra 7% predicted demand. Meeting that demand, however, is becoming more and more challenging as ores are becoming lower grade, deeper, and more complex.
This implies that there is an urgent need to optimise current processes to extract the necessary minerals and metals more sustainably and efficiently. As froth flotation is a large-scale process, even small improvements in the separation efficiency would translate into important increments in production.
Overflowing froth seen from the top of an industrial-scale tank. Image by @AMPRG_Imperial.What is the potential of this work in terms of copper recovery?
We demonstrated that improvements of between 8 to 22% in metal recovery were achieved by implementing a model predictive control strategy at the laboratory scale, revealing an untapped potential for implementation at an industrial scale. This research could serve as a promising next step for the mining industry to meet future metal and mineral demands by extracting more metal for the same amount of resources, such as water, energy, and chemicals.
>> Interested to find out more about SCI Scholarships?
Your flotation tanks are actually based in Chile. How do you operate them remotely?
I am currently implementing an online model predictive control strategy in a laboratory-scale flotation bank in Chile. I monitor and control this experimental rig from home, in the UK.
The experimental rig was automated in such a way that all the instruments (e.g. air flow meters, controllers, pumps, etc.) are connected to a module called ‘Programmable Logic Controller’. This module is then connected to a workstation computer, which I access from my laptop in the UK.
The Programmable Logic Controller allows me to obtain measurements in real-time and control the system. In this case, the measurements are used to update the mathematical models, while the system is controlled by changing the ‘revolutions per minute’ of the pumps (to change the pulp levels) and/or moving the air valves (to change the airflow rates).
Experimental campaign in 2018 – aerial view of a 300m³ froth flotation tank. Image by @AMPRG_Imperial.
Could this process be used to extract other materials? If so, which ones?
While froth flotation is widely used to separate sulphide minerals of copper, it is also used to separate other sulphides, such as those containing lead, zinc, and molybdenum.
You won an SCI Scholarship. How did you use the funds you received to develop your research?
I used the generous SCI scholarship to partially fund a two-month visit to the laboratory in Chile. I set up new connections for remote control by installing new instrumentation to make it even more automated, and I carried out preliminary online control experiments. Since then, all the control experiments have been carried out from my laptop at home.
I also used the scholarship to fund my participation in several conferences, including one in person in Athens, Greece, in 2021. I have participated in Scholar Days in 2020 and 2021, in which I presented advances in my PhD research to a wide audience. This year, I presented my PhD research results at SCI headquarters for the first time and participated in the Poster Showcase, where I won first place.
Paulina presenting at the SCI Scholars' Showcase in July 2022. Image: SCI/Andrew Lunn
What are your future plans for this innovative technology (and other potential research)?
I plan to keep up the momentum of researching froth flotation optimisation, as I believe that there is still a long way to go for improvement, particularly at an industrial scale. Model predictive control has not been widely explored within the mineral processing industry despite the fact that it has shown great potential. There is still a gap between academia and industry that should be bridged, sooner rather than later, to improve the performance of the process.
Apart from the model predictive control strategy using physics-based models (including the one I have investigated during my PhD research), many other control strategies show great potential to be tested and implemented at an industrial scale.
This is particularly applicable in mineral processing plants, as most of them collect a huge amount of data that could serve as valuable inputs for further improvement and optimisation, using novel engineering tools such as artificial intelligence and digital twins.
Paulina is part of the Advanced Mineral Processing Research Group at Imperial College London, whose research includes fluid dynamics of flotation tanks and multi-criteria decision-making for sustainable mining and mineral processing.
A range of greenhouse gas removal technologies may be necessary if we’re to reach Net Zero by 2050. In the second of our two-part geoengineering feature, Eoin Redahan looks to the sea, the sun, and mineral weathering, and at the ethical concerns such technologies raise. Missed Part One? Find it here.
‘Water, water, everywhere, nor any drop to drink.’
These famous words from Samuel Taylor Coleridge’s Rime of the Ancient Mariner aren’t the only famous part of his epic poem. The term albatross around one’s neck comes from it too.
After shooting a friendly albatross at sea, the poem’s narrator was forced by the ship’s crew to wear the dead creature around his neck – and grievous luck was to follow. Well, our blue planet has an albatross around its neck in the form of climate change.
Perhaps the solution to it lies all around us – water, water, everywhere…
In theory, we can use our oceans to pull CO2 from the air on an enormous scale. All it may take is clever intervention – potentially ruinous, albatross-shooting intervention.
Nevertheless, the World Economic Forum lays out the tantalising potential. ‘Ocean-based CO2 removal can help us achieve “net negative emissions” as the seas hold 50 times more carbon than the atmosphere,’ it says.
‘The ocean [is] a sink for nearly one third of anthropogenic carbon emissions and more than 90% of the resulting heat… If we are going to manage atmospheric CO2 levels to our advantage, we will need to leverage the ocean’s existing ability to govern the global carbon cycle.’
Frontier has targeted the development of scalable sources of alkalinity. The reasoning behind it is that with CO2 being an acidic molecule, rising CO2 concentrations could be neutralised through alkalinity. It has mentioned using mine tailings to remove up to 0.5 gigatonnes of CO2 from the air each year; but the major caveat here is that it needs to be done safely.
Planetary Technologies has ventured into this space armed, essentially, with a bicarbonate of baking soda that could draw in CO2 and sequester it for millenia.
The company explains its process: ‘We start by carefully extracting key parts of the mine tailings including recovering battery metals (like nickel and cobalt) and silica (sand) and then take the remaining purified metal salt solution into a special electrolyser. There, using clean, renewable electricity, the salt and water are split to make hydrogen (a clean, emissions-free fuel), and a pure alkaline hydroxide.
‘It’s from this point that we transport the bulk alkaline materials to our ocean outfalls site where the alkalinity is introduced to the surface ocean that then draws in CO2, sequestering it as already abundant bicarbonate and carbonate ions in seawater.’
So, by decreasing the acidity of the ocean, it would have a greater capacity to absorb CO2 from the air. The key, however, is to reduce this to a viable price point.
>> Want to read about iron fertilisation in our oceans? Rhiannon Garth Jones took a closer look here.
Mineral weathering is another contender in the CO2 removal mix. One technology that recently received $2.4m in funding is Seattle-based Lithos’ enhanced weathering process – a mineral weathering process that could capture CO2 at a gigatonne scale. According to Frontier, Lithos spreads basalt on croplands to increase dissolved organic carbon, before eventually being stored as ocean bicarbonate. The idea is to maximise CO2 removal while bolstering crop growth.
Closer to home, SAC Consulting in Edinburgh will receive £2.9m to capture the methane produced by cattle and cut emissions from the livestock farming sector; Synthetic Biology in San Francisco has received an R&D grant to synthesise a polymer within algae that is capable of sequestering atmospheric CO2 at a large scale; and Charm Industrial is converting plants into a carbon-rich liquid that is pumped underground.
To do the latter, Charm grows cellulosic biomass that captures CO2 from the atmosphere. It is then harvested, ground, and heated, before being turned into a bio-oil that is pumped underground.
Even the concrete beneath our feet could be used as a carbon sink. CarbonCure is injecting CO2 into its concrete mixes, which it says is not only comparable in cost to traditional concrete, but stronger.
And then, we have solar engineering – arguably the first technology that comes into many of our minds when we think of carbon removal. All sorts of geoengineering technologies exist in this sphere including cirrus cloud thinning, stratospheric aerosol scattering, and marine cloud brightening.
Interestingly, Harvard’s Solar Geoengineering Research Programme referred to geoengineering as ‘a set of emerging technologies that could manipulate the environment and partially offset some of the impacts of climate change’.
Therein lies the problem for many. What are the consequences of ‘manipulating the environment’, especially if these technologies fall into unscrupulous hands?
In her excellent blog for SCI on geoengineering, Rhiannon Garth-Jones referred to the Haida Corporation Salmon trial. In this trial, 120 tonnes of iron compound were deposited in the migration routes of pink and sockeye salmon in the Pacific Ocean, which resulted in a several-month-long phytoplankton bloom.
It was seen by many as a success. The phytoplankton fed fish and increased biodiversity and the iron sequestered carbon; but Environment Canada believed the corporation violated national environmental laws by depositing iron without a permit.
History teaches us that profit vs. planet tussles don’t always go the way we would like, and the consequences of these technologies going into the wrong hands could be catastrophic.
On 29 June, The World Economic Forum called for a code of conduct for ocean-based CO2 removal; and the American Geophysical Union, a group of climate and planetary scientists, is leading the way in developing an ethical framework for climate intervention engagement.
We’re all feeling the effects of climate change. As I write this piece on 19 July, it is 39°C here in Greenford, London. 39°C in London! The earth is cracking, planes are circling (because the runways are melting), and grass fires are blazing in Croydon.
On days like today, it feels like we need all the innovation we can get.
From the Black Death to the Covid-19 pandemic, great adversity has also led to great advances. So, which inventions have emerged from times of hardship? Eoin Redahan finds out.
‘World events shape innovations. The World Wars shaped innovation, and the pandemic has shaped innovation,’ said Paul Booth OBE, in his outgoing speech as SCI President.
‘It is possible to accelerate innovation – we’ve demonstrated that.’ Paul Booth OBE, outgoing SCI President at SCI’s AGM, July 2022. Image: SCI/Andrew Lunn
The pandemic taught us a lot about ourselves. It taught me that eating my body weight in sweets was a great way to destroy my teeth, and it brought home to many the futility of the five-day commute. On a more abstract level, it taught governments and policy makers just how much can be achieved in a short space of time when necessity demands it. The vaccines that swam around our veins bore testament to this.
The pandemic has shaped innovation. Nowhere is this more apparent than in medicine. It isn’t the first awful event to provide a hotbed for change, and it won’t be the last. ‘It is possible to accelerate innovation,’ Paul said. ‘We’ve demonstrated that.’
As bad as the Covid-19 pandemic was, the Black Death makes it look very tame indeed. It is estimated that the Plague, which was its worst from 1346-53, took up to 200 million lives in Eurasia and North Africa.
Amid the carnage, it is also said to have given us a system to mitigate infectious diseases with which we are familiar, including isolation periods. According to Britannica, ‘public officials created a system of sanitary control to combat contagious diseases, using observation stations, isolation hospitals, and disinfection procedures.’
The terrifying doctor will see you now.
The Plague also said to have inspired greater experimentation in pharmacology. In a sense, it also helped democratise medicine, with medical textbooks shifting from Latin to the vernacular. As John Lienhard, at the University of Houston, noted: ‘Both medical and religious practice now shifted toward the laity.’
But perhaps the most memorable advance from this time was the strange, beak-like masks worn by some doctors during the Plague. These masks were a crude (and frankly terrifying) way to protect the doctors from the disease in the air. The doctors even filled these masks with herbs in an effort to protect against pathogens.
Of course, wars have also led to military innovation at breakneck speed. During the American Civil War, the Minié ball was created. It spun faster than other bullets and could travel half a mile – unlike pre-Civil War bullets, which went a mere 300 feet.
Officers of a monitor-class ironclad warship, photographed during the American Civil War.
This war also led to the ironclad warship, with plates riveted together to protect against cannonballs. However, it should also be noted that many of the most interesting war-borne inventions have ended up having little or nothing to do with military application.
The ‘cotton-like-texture’ of cellucotton led to its brand name Kotex. According to this 1920 advertisement, this ‘wardrobe essential of Her Royal Daintiness’ was available at any shop that catered to women. Different times.
World War I gave us the blood bank, the Kleenex, the trench coat, and the sanitary pad. The sanitary pad has peculiar origins. In 1914, the war resulted in cotton shortages and substitutes were needed. Kimberly-Clark executives duly discovered a processed wood pulp material that was five times more absorbent than cotton, and cheaper to make. The material was used for bandages, and Red Cross nurses realised that this material could be used as makeshift sanitary pads. The company then developed a sanitary pad – branded Kotex – made from cellucotton and a fine gauze.
Material substitution also led to ground-breaking innovation in World War II. According to the National WWII Museum New Orleans, in 1942 Japan cut off the US supply of natural rubber. With the demand for rubber high, US President Franklin Roosevelt invested $700m to make synthetic rubber from petrochemical byproducts at 51 new plants. By 1944, these synthetic rubber plants were producing 800,000 tonnes of the material a year.
Duct tape was developed by Johnson & Johnson during the Second World War, and by 1972 the ubiquitous tape had reached the moon. This makeshift wheel fender repair helped the Apollo 17 mission’s lunar rover to keep lunar dust at bay.
We use many other products invented during the Second World War, including duct tape, which was developed by Johnson & Johnson to keep moisture out of ammunition cases. A fellow called Harry Coover discovered cyanoacrylates – the active ingredient in Super Glue – while he tried to create a clear plastic for gun sights.
And the next time you reheat your dinner, spare a thought for Percy Spencer, the US physicist who noticed the candy bar melting in his pocket when he stood next to an active radar set. This moment of epiphany led to an invention you might know: the humble microwave.
Just as these trying times lead to extraordinary leaps in technology, they also lead to the large-scale rollout of said discoveries. A prime example of this is penicillin. It was first used to treat an eye infection in 1930, but it was only with the horrific fall-out of war that experiments with deep tank fermentation led to its widespread production.
A soldier recuperates in hospital thanks to penicillin in this Second World War poster. Note the not-quite-so-life-saving hospital bed cigarette. Different times, again.
The Penicillin Production through Deep-tank Fermentation paper in ACS notes that: ‘During World War II, the governments of the United States and the UK approached the largest US chemical and pharmaceutical companies to enlist them in the race to mass produce penicillin […] One of these companies, Pfizer, succeeded in producing large quantities of penicillin using deep-tank fermentation.’
The speed of development and global-scale rollout of vaccines against Covid-19 was unprecedented. Science, business and governments worked together to get the world moving again.
And, as we all know, Pfizer was back at it again during the Covid-19 pandemic. Along with AstraZeneca, Moderna, and essentially the entire pharmaceutical industry, it created vaccines that saved countless lives. Governments and policymakers were also reminded just how quickly life-saving technologies can be pushed through when needed.
But the legacy of Covid-19 treatment will stretch further, be it in nanotechnology, artificial intelligence, or other fields – who knows what else will come from it?
As Paul Booth said: ‘It is possible to accelerate innovation. We’ve demonstrated that.’
Many believe that greenhouse gas removal technologies will be necessary if we’re to reach net zero by 2050. In the first of our two-part geoengineering feature, we look at some of the difference-makers.
This week, a friend of mine played a tennis match just north of London. The game was due to take place at 18:00 but was deferred for an hour because it was 39°C. This came a day after Rishi Sunak, who may become the UK’s next Prime Minister, warned about going ‘too hard and too fast’ on net zero measures.
It’s looking increasingly likely that the implementation of environmental policies isn’t happening quickly enough; so, if we want to avoid catastrophic climate change, we will need to develop technologies that pull carbon dioxide from the atmosphere.
Mercury rising: the UK recorded record high temperatures this week.
Certainly, that’s the UK government’s perspective. ‘Greenhouse Gas Removal technology will be essential to meeting the UK’s climate change target of net zero carbon emissions by 2050,’ it said. ‘These technologies will be necessary to offset emissions from hard to decarbonise areas, such as parts of the agriculture and aviation sectors.’
Thankfully, work is underway to make this happen. And it is more than just the pang of the environmental conscience that has stirred the private sector into action. There is much money to be made from geoengineering. Indeed, a CNBC story has estimated that it could be a trillion dollar market by 2050.
The public investment has been relatively modest by some. The UK government recently pledged £54m in funding towards 15 different carbon removal technologies. But some in the private sector have dollar signs in their eyes.
A collaborative called Frontier – funded by Stripe, Alphabet, Shopify, Meta, McKinsey, and tens of thousands of businesses using Stripe Climate – has made an advance market commitment to spend an initial $925m on permanent carbon removal technologies between 2022 and 2030.
‘Models project that by 2050 we will need to permanently remove billions of tons of CO2 from the atmosphere every year,’ it states. ‘To date, fewer than 10,000 tons have been removed in total.’ The capital it has committed is designed to help companies developing carbon removal solutions to scale up.
The UK government has mentioned the need for a portfolio of carbon removal technologies to reach net zero. A cursory look reveals that there are many from which to choose, including direct air capture, the manipulation of the sea, advanced weathering, and solar engineering.
These methods are audacious, exciting, and controversial.
The key, as ever, is to come up with low-carbon technologies that are both effective and economically viable. In that respect, direct air capture has emerged as a front runner. This technology often uses giant fans with filters, or chemical processes, to take CO2 from the air.
The difficulty is the amount of energy needed to power these processes and the source of this energy. The cost of removing each tonne of CO2 is also an impediment to growth – something that will need to fall for it to be implemented on a large scale.
Climeworks co-founders Jan Wurzbacher and Christoph Gebald at the Orca plant in Iceland. Image courtesy of Climeworks.
Nevertheless, significant strides have been made in recent times. Swiss company Climeworks raised US$650m in equity for its largest direct air capture plant, and last week it inked a 10-year deal with Microsoft to permanently remove 10,000 tonnes of CO2 emissions from the atmosphere on its behalf.
The company’s machines capture CO2 from ambient air by drawing air into the collector with a fan. The CO2 is captured on the surface through a selected filter material that sits inside the collectors. Once the filter is filled with CO2, the collector is closed, and the temperature is increased to 80–100°C, whereupon the CO2 is released.
And what becomes of the CO2 after that? The CO2 at its Orca facility (50km outside Reykjavík, Iceland) will be mixed with water and pumped deep underground. The carbon dioxide will then react with the basalt rock through natural mineralisation and turn into stone.
Climeworks CO2 turned into stone via Carbfix technology. Image courtesy of Climeworks.
And Climeworks isn’t the only one operating in this space. As part of the UK Government’s aforementioned £54m funding, London-based Mission Zero Technologies will receive £2.9 million to build a low-energy, heat-free way to pull CO2 from the air.
Sydney-based AspiraDAC has been backed by the Stripe Climate Fund to remove 500 tonnes of CO2 using its modular, solar-powered system. According to Frontier: ‘Its MOF (metal-organic framework) sorbent has low-temperature heat requirements and cheap material inputs, increasing the likelihood that AspiraDAC can help accelerate the production of lower-cost metal-organic frameworks which, historically, have been expensive and difficult to synthesise.’
The Stripe Climate Fund has also backed 8 Rivers Capital, LLC, and Origen Carbon Solutions, Inc to remove CO2 from the air using its direct air capture (DAC) technology. Frontier said: ‘The DAC technology accelerates the natural process of carbon mineralisation by contacting highly reactive slaked lime with ambient air to capture CO2. The resulting carbonate minerals are calcined to create a concentrated CO2 stream for geologic storage.’
Of course, direct air capture is just one of many CO2 removal solutions. In part two, next week, we’ll look at other promising technologies.
What is the verdict on the 100% sustainable fuel Formula 1 plans to use in its cars, and is the new E10 fuel this season doing any good? We asked David Bott, SCI’s Head of Innovation.
Beware of Greeks bearing gifts. This phrase comes from Virgil’s Aeneid, and it refers to the Greeks’ gift of a giant wooden horse to their enemies during the Trojan War. But this was no gift at all.
This warrior-filled, hollow wooden horse that the Trojans wheeled inside the gates of Troy was a ploy from the Greeks to get inside the city’s impenetrable city walls and ambush their enemy. It turned out things weren’t quite what they seemed.
Just as Trojans became wary of giant wooden horses, we should be wary of Net-Zero pledges. These promises seem impressive but, if you look inside, they might not be quite as beneficial to the environment as advertised – at worst, they could be hollow.
Whenever an organisation talks of carbon credits, makes a vague reference to biomass or a grand pledge with little detail, it is worth closer investigation.
Formula 1 recently made a sustainability pledge of its own. Following its decision to use E10 fuel in the cars this season (a mixture of 90% fossil fuel and 10% ethanol), it has announced plans to use a 100% sustainable drop-in fuel in its vehicles as part of its plans to reach Net-Zero by 2030.
On first reading, the terms Net-Zero and Formula 1 don’t sit easily together. Isn’t this the sport where 20 cars can burn more than 100kg of fuel each per race? The same travelling circus in which cars, teams, and drivers are flown and ferried all over the world for more than eight months of racing?
By its own calculation, in a November 2019 report, Formula 1 is responsible for 256,551 tonnes of carbon dioxide emissions each year. To put that figure into perspective, you would need to drive for 6,000km in a diesel car to generate a single tonne of carbon emissions – multiply that by 256,000, and Net-Zero feels some distance away.
Both Formula 1’s new fuel and pledges merit closer inspection. Regarding the move to the E10 fuel in Formula 1 cars, David Bott, SCI’s Head of Innovation, wasn’t exactly gushing.
‘E10 is an evolutionary backwater – adding just 10% ethanol does nothing for emissions,’ he said. ‘A quick enthalpy calculation shows the energy in the fuel has decreased, so you need more.’
The proposed move to a ‘100% sustainable drop-in fuel’ used in standard internal combustion engines is seen by many as a positive move. Formula 1 says the fuel will be made using components from either carbon capture, municipal waste, or non-food biomass.
Each of these ‘components’ on its own is worth exploration. For example, what types of municipal waste do they mean, which types of non-food biomass are they talking about, and what about the manufacturing process?
Biomass fuel is controversial due to concerns over carbon sequestration and land use.
The passage of time will reveal more but, again, David has questioned the green credentials of the proposed fuel. He said: ‘What Formula 1 is proposing to do is analogous to sustainable aviation fuel – to make octane from a non-fossil source of carbon.’
‘[To do this], you can use biomass or “synthetic”, which basically means distillate plastic waste. It is effectively using fossil carbon that was used for something else; so, it doesn't make the situation any worse, but neither does it really contribute to lowering emissions. It’s just short-cycle carbon.’
The mention of aviation is pertinent when it comes to Formula 1. The emissions generated by the 10 teams’ vehicles across 21 Grands Prix, including races and testing, account for just 0.7% of Formula 1’s total emissions. But by far the biggest contributor to its CO2 emissions are logistics – the movement of equipment from venue to venue by land, sea, and air.
The equipment used in Formula One must be transported from continent to continent by sea, land, or air.
After that comes business travel at 27.7%, which includes the air and ground transportation of all individuals, as well as the hotel footprint from all Formula 1 teams’ employees and major event staff. So, it’s clear that the main environmental problem isn’t the fuel used during the races; it is all of the other transport emissions.
To be fair to Formula 1, the sport has made an effort to make operations greener, including powering its offices using 100% renewable energy and taking measures to make freight more efficient.
However, any claims that it is motoring to Net-Zero by 2030 need to be chased with a liberal swig of scepticism. A Net-Zero 2030 goal provides a nice headline, but how you get there is the story.
Fossil fuels don’t just keep our motors running. They don’t just heat our homes. They form the basis of many of our everyday products.
Problem is, fossil carbon is cheap and reliable. Nevertheless, bit by bit, many companies are weaning themselves off petrochemical feedstocks.
For Unilever, that means dishwasher liquids with cleaning agents made from fermented sugar. For Croda, it means using corn to create a bio-ethylene oxide that can replace some surfactants in its personal care products.
So, what other moves have organisations made lately to create greener feedstocks?
1. Castor seed building blocks
Arkema is using castor seed in a huge range of products.
Arkema has received certification for its castor seed-based materials in products that include cosmetics, fragrances, lubricants, and pharmaceuticals.
The Paris-based speciality materials company says it will use castor seed for 100% of its monomer, polymer, and oleochemical production in its plant in Singapore.
Part of the problem with developing green feedstocks is making them financially viable and resilient. Growing these feedstocks sustainably is also important. For example, palm oil contains many products that make it a useful feedstock for those in the chemicals industry, but the way it is farmed, and its effect on the soil, are routinely criticised.
To that end, Arkema says that 13,300 hectares used to grow its crops (primarily in Western India) are sustainably farmed under the Sustainable Castor Caring for Environmental and Social Standards code.
2. Nutrient recovery
Unused nutrients from agriculture could be turned into biofertiliser.
The US Environmental Protection Agency (US EPA) is taking part in a project with Northwest Florida Water Management District and May Nursery that will demonstrate nutrient recovery technology.
According to the US EPA, the aforementioned parties will demonstrate how unused nutrients from agriculture can be captured and turned into a biofertiliser that will help farmers along the way to more circular agricultural processes.
>> How do we make a large-scale move to greener feedstocks? Several of SCI’s Corporate Partners weighed in on the issue.
3. An alternative to plastic wrapping
Thyme oil’s antimicrobial properties could help extend the shelf life of fresh food.
Researchers at Rutgers and Harvard have created a plant-based spray coating for fresh food packaging, which they believe could reduce our reliance on petroleum-based packaging.
The researchers liken their technology to the webs that shoot from Spider-Man’s wrist. Their stringy material is spun from a hair-dryer-like heating device that is shrink-wrapped over foods as diverse as avocado and sirloin steak.
Their biopolymer contains natural antimicrobial agents – thyme oil, citric acid and nisin – to fight spoilage. The wrapping can also be easily rinsed off and degrades in the soil within three days.
4. Degraded by the light
North Dakota researchers have developed a plastic that degrades in a wavelength of light not contained in the spectrum of sunlight on earth.
Biodegradation is a prickly issue. Many are sceptical about the way biodegradable plastic bags interact with the natural environment, and others argue that we should focus on upcycling products rather than downcycling them.
That’s partly what makes a new bio-based vanillin plastic so interesting. A team of US researchers from the Center for Photochemical Sciences, Bowling Green State University, and North Dakota State University has created lignin-based polymers that degrade when exposed to light of a specific wavelength – a wavelength not contained in the spectrum of sunlight that reaches the earth.
The result of this, they claim, is that up to 60% of the monomers could be polymerised again with no loss of quality. So, in theory light-triggered degradation could make it much easier to re-use these materials.
>> Natural materials, such as hemp, are becoming ever more important. So, what makes it so special?
Is it dipping your finger into a glistening bowl of mercury? Is it symmetry? Is it the patterns of crystal growth or is it to be found in nature – in the neatness of evolution? In his thought-provoking SCItalk, Philip Ball explored the beauty of chemistry.
When you write fiction, you’re supposed to wake all the senses. So, don’t just tell readers what something looks like. Tell them how it feels. Tell them how it sounds. Tell them how it tastes. For beauty exists in the smell of perfume as someone walks by, just as it resides in the colours of bloom. One of the beauties of chemistry – like nice writing – is that it also evokes all of the senses.
That was what drew Philip Ball to chemistry: the profusions of colour, the explosions, the reek of sulphur, dipping his finger into a bowl of mercury as a lad and wondering how this dense, silvery liquid hadn’t made his hand wet.
And yet, chemists – and scientists in general – seem to have a complicated relationship with beauty. Part of this is down to what different groups see as beautiful. ‘When scientists talk about beauty,’ he said, ‘they think they’re talking about what artists are, but they really aren’t.’
A chemical garden formed from copper nitrate in sodium silicate solution by Yan Liang and Wenting Zhu.
For a physicist, an equation might capture the essence of beauty. For a chemist, it might be the shape of a crystal growth formation. Ball argued that chemists tend to be Platonists – that they locate beauty in symmetry (for Plato, he added, art was too messy ever to be beautiful).
Chemistry’s reputation as a staid science isn’t helped by the fact that it has long hidden its light from the world. Much beauty is confined to those who view it under microscopes. It is only relatively recently – with the proliferation of high-resolution imagery – that the public has finally looked upon the beauty of chemical gardens, processes, and configurations in all their stunning detail.
Even so, despite the bewitching quality of seeing copper hydroxide billowing like a jellyfish, and the jagged architecture of lead formations, much of chemistry’s beauty lies in its dynamism, rather than the confines of the still frame.
And yet, it wasn’t ever thus. Chemistry in bygone centuries was viewed slightly differently. ‘Of the chemistry of his day and generation, [the German philosopher] Kant declared it was a science, but not Science,’ Ball noted.
Similarly, in Frankenstein, Mary Shelley painted chemistry in a different light to how it is seen today. ‘Chemistry is that branch of natural philosophy in which the greatest improvements have been and may be made,’ her character, Professor Waldman, said.
The sheer beauty in science has long been appreciated, as is seen in this cyanotype photogram made by Anna Atkins in her 1843 book, Photographs of British Algae: Cyanotype Impressions.
So, why the small s? Why was it seen, not as a soft science, but one with a softer underbelly – like a stone-faced steel worker who secretly writes poetry? Perhaps it has to do with the link to creation. ‘Chemists display, arguably, the greatest creativity in the sciences,’ Ball said. ‘[They have] the urge to make stuff.’
This creativity is often guided by the beauty of the natural world. Ball argues that some scientists are guided by the sheer beauty of nature, by finding the unexpected in things we have seen so many times before.
On the screen, he put up a picture of what looked like the intricate component of a motor, which turned out to be the natural motor structure within bacteria driving its very survival. He mentioned the pigments within flower petals, so delicately tuned by evolution.
An extraordinary bacteria motor (left). Image from paper on: Structural basis of assembly and torque transmission of the bacterial flagellar motor. Created by Zhejiang University researchers..
Simply put, the elegant solutions found by nature are inspiring. ‘It made me think about what Einstein said,’ he added. ‘The Theory of Relativity was so beautiful to him that he believed nature had to work this way.’
And some chemists are drawn by a different type of aesthetic: the beauty of the method. Just as a football fan might rhapsodise about the arc of a perfectly struck free-kick as it curves beyond the keeper’s reach, some chemists see something in the process. ‘For some chemists, there’s a beauty in the synthesis,’ Ball said; and other chemists, he added, will have their own aesthetic responses to an approach, be it elegant or otherwise.
Why shouldn’t the work of a chemist be driven, in part, by beauty? And why should the arbiters of the aesthetically pleasing be confided to the arts? For Philip Ball, the chemical world is one of artistry, dynamism, and beauty. For him, science provides a new lens, new tools for seeing, and new ways for looking at the world around us.
‘Science doesn’t de-enchant the world,’ he said. ‘On the contrary, it re-enchants it.’
Philip’s book, The Beauty of Chemistry, is published by MIT Press.
Have you ever seen a snowflake up close? Have you smelt fertiliser on a country drive? Chemistry is the most sensuous of the sciences, and it may just be the most beautiful too. In our latest SCITalk, Dr Philip Ball showcases the breathtaking beauty of chemistry.
Main image: A chemical garden formed from copper nitrate in sodium silicate solution by Yan Liang and Wenting Zhu.
Even the most disciplined of us falls into these rogue states from time to time, minutes of total absorption unrelated to work or duty. For some, it is the humble cat video. For others, it is the endless tapestry of Twitter.
Crystals of nicotinic acid by Yan Liang and Wenting Zhu.
For me, this morning, it was a time-lapse video of crystal growth patterns. The world temporarily stopped moving as I fell headlong into high-resolution pictures of icy fronds appearing and clusters of spikes combining to form crystalline towers. Who knew potassium nitrate, ammonium chloride, and monopotassium phosphate could be so beautiful?
It turns out, Dr Philip Ball did. He knows all about the beauty of chemistry – from its profusions of colour to the hypnotic beauty of snowflakes forming.
Oxygen bubble from decomposing hydrogen peroxide by Yan Liang and Wenting Zhu.
Dr Ball argues that chemistry is the most sensuous of the sciences. Which of us hasn’t smelt the stink of sulphur or the sting of ammonia in our nostrils? When he unveils vivid, other-worldly pictures of chemical gardens, or even when we see a close-up of water being added to a bowl of M&Ms, it’s hard to disagree with his view.
This Wednesday evening, 25 May 2022, Dr Ball will deliver his SCI Talk about the beauty of chemistry and his book of the same name, which he put together with photographers Yan Liang and Wenting Zhu. Using microphotography, time-lapse photography, and infrared thermal imaging, they have captured astonishing photos of chemical processes.
They have captured a beauty seldom seen, except by chemistry’s day-to-day practitioners. They show us the chemistry of champagne in a new light and the transformations of evaporation and distillation. They unveil the strange world of chemical gardens – from the blue tendrils of copper nitrate in sodium silicate solution, to the silky precipitation of silver chromate.
Precipitation of silver chromate by Yan Liang and Wenting Zhu.
Some defend the beauty of science by conflating it with the pursuit of truth. As the famous snippet from Keats’ Ode on a Grecian Urn goes: ‘Beauty is truth, truth beauty.’ Yet, it’s clear that the beauty of chemistry does not need to be defended in such abstract terms. It’s there in champagne bubbles and the deft configurations of a snowflake. You just need to look into a microscope - or plunge mind-first down a YouTube rabbit hole.
Register here to watch the Beauty of Chemistry SCItalk this Wednesday 25 May 2022.
By rethinking the way our products are designed and changing the way we use plastics, we can tackle the blight of marine litter and the general accumulation of plastic waste. But, as Professor Richard Thompson said in our latest SCItalk, systemic issues and historical excesses have made this no easy task.
Contrary to popular perception, plastic is not the villain. When it comes to marine littering, we are the ogres, with our single-use bottles bobbing in the oceans and the detritus of our everyday lives littering the coastline.
We are the reason why 700 species are known to encounter plastic debris in the environment. It is because of us that plastics have beaten us to the bottom of the deepest oceans and glint in the sun near the summit of Mt. Everest.
According to Richard Thompson, of the Marine Institute School of Biological and Marine Sciences at the University of Plymouth: ‘Plastic debris is everywhere. Its quantity in the ocean is likely to triple between 2015 and 2025.’
As Professor Thompson pointed out all of these facts to his audience in our latest SCItalk on 23 March, he outlined potential solutions. However, there is no ignoring the depth of the issues at hand when it comes to the litter in our seas.
Society has gradually woken up to the menace of discarded plastics and, laterally, to the threat of microplastics and nanoplastics. The problem is that we left the barn door open decades ago. So, all of those plastic microbeads from shower gels, fibres from clothing, and tyre wear particles polluted our seas for many years before it came to public and scientific attention.
Professor Thompson said that 300 papers were published globally on microplastics in the last academic year alone, but research in the area was relatively thin on the ground before Thompson and his colleagues released their pioneering study on microplastics in Science in 2004.
‘The business model for the use of plastics hasn’t really changed since the 1950s,’ Professor Thompson said. According to him, we have had 60 years of behavioural training to just throw products away, and our waterways reflect this attitude.
According to Professor Thompson, 50% of shoreline litter items recorded during the 2010s originated from single-use applications. Without a sea change in our attitude towards single-use items, this problem will persist.
>> Why are we ignoring climate change and what can we do about it? Read more on our blog post.
Microplastics have been subject to great scrutiny, but much of the research is quite recent.
The problems with larger plastics and even microplastics are now well documented. The worrying thing, according to Thompson, is that there are knowledge gaps when it comes to nanoplastics in the natural environment. What are the effects of nanoplastic ingestion? What are the effects of human health? Time will tell, but Thompson was keen to ask if we really need that information before we take action.
He was more sanguine about the effects of microplastics. ‘The concentration of microplastics is probably not yet causing widespread ecological harm,’ he said, ‘but if we don’t take measures, we’ll pass into widespread ecological harm within the next 50-100 years.’
It seems counterintuitive to think of petrochemical plastics as a sustainable solution; and yet, despite the environmental problems posed by their durability, they do have a role to play in a greener approach.
‘If used responsibly, plastics can reduce our footprint on the planet,’ Thompson noted. Indeed, the lightweight plastic parts in our cars and in aviation can actually help reduce carbon emissions. But despite their merits, how do we keep plastic litter from our seas?
To illustrate a flaw in the way we design plastic products, Professor Thompson gave the example of an orange coloured drinks bottle. While the bright colour may help sell juice drinks, there is an issue with recycling these coloured plastics because their value as a recyclate is lower. Clear plastics, on the other hand, are much more viable to recycle.
He argues that many products aren’t being designed with the whole lifecycle in mind. ‘We’re still failing to get to grips with linking design to end of life,’ he said, before highlighting the importance of communicating how products should be disposed of right from the design stage.
Basically, our products should be designed with end of life in mind. ‘If we haven’t even designed a plastic bottle properly,’ he lamented, ‘what hope do we have with something that’s more complicated?’
Those brightly coloured plastic bottles look nice and fancy, but they can be challenging to recycle in a circular economy.
Professor Thompson argued that better practices are needed to help divert materials away from our seas (and it should be noted that there are other types of discarded materials to be found there). If we recycle greater quantities of end of life plastic products and bring them into a circular economy, he said, ‘we’d decouple ourselves from oil and gas as the carbon source for new production because the carbon source we use would be the plastic waste’.
He said more could also be done with labelling so that customers know whether, for example, a product is compostable and which waste stream it needs to be placed in to achieve that. He also noted that addressing our single-use culture would be a good place to start if we want to change the business model of linear use.
The good news is that there is an appetite for change. ‘Ten years or so ago there was no consensus that there was a problem,’ Thompson noted. ‘I would argue that this has changed.’ However, he also feels that it is essential to gather reliable, independent evidence to inform interventions, rather than espousing solutions that could make things worse.
‘We need to gather that evidence from different disciplines,’ he said. ‘We need to have at the table product designers and couple them with the waste managers. We need to have economists at the table. We also need to bring in social scientists to look at behaviour. We’ve got to think about this in the round.’
He also felt that policy measures – such as mandating recycled content – could be a good option, along with better design and disposal.
The tools we need to tackle plastic pollution are already at our disposal. We just need to act more responsibly – which, unfortunately, has been part of the problem all along.
As Professor Thompson said: ‘It’s not the plastics per se that are the problem – it’s the way we’ve chosen to use them.’
>> For more interesting SCI talks like Professor Thompson’s, check out our YouTube channel.
>> Find out more about the work of Professor Thompson and his colleagues here: https://www.plymouth.ac.uk/research/marine-litter.
There was a happening in York recently – a Hemp Happening – organised by SCI’s Agrisciences Group and Biovale. It took place at York’s STEM Centre and explored the issues around growing and using industrial hemp. Despite these issues, there is a growing demand for hemp fibre and shiv as we look to use sustainable natural fibres and move to a low-carbon economy.
In 10 years’ time, you’ll walk out of your hemp-insulated home, wearing your hemp fibre t-shirt, polishing off the last of your hemp and beet burger, before heading to work in your hemp seed oil-powered car.
Is this scenario fantastical? Yes, obviously, but as delegates attending Hemp Happening explained on 6 April, all of these products exist right now. The sheer breadth of them underlines what a useful and versatile material hemp is. If enabled through policy, hemp could play a big part in our low-carbon future. Here are five ways it could make a significant difference.
Hemp has much-vaunted carbon-sequestering potential which, given our climate change travails, could prove extremely useful. Some experts say it is even better at capturing atmospheric carbon than trees. According to SAC Consulting, industrial hemp absorbs nine to 13 tonnes of CO2 per hectare. To put hemp’s absorption capacity into context, hemp market specialists Unyte Hemp said it absorbs 25 times more CO2 than a forest of the same size.
Of course, that’s all very well, but how do you make sure this carbon remains sequestered?
One fitting home for hemp (and the carbon it has captured) is in construction, especially given the carbon-intensive nature of the industry. So, with the pressure intensifying to replace and retrofit the UK’s inefficient building stock, hemp is well placed to reduce emissions and improve building performance.
Hemp is not just used in insulation materials due to its excellent thermal performance characteristics. It is also used in rendering buildings and for non-load bearing blocks in construction. Indeed, hempcrete blocks, which are made from hemp shiv, lime, and sand or pozzolans, have a net carbon negative footprint.
Hemp is used in everything from food supplements to medicines, cosmetics, and construction products.
Hemp also helps the earth. As flash flooding strips our soils, the plant’s root density and deep structure protects against soil erosion and mitigates compaction. Hemp also provides nutrients to help maintain soil health, making it useful in crop rotation.
As insect populations dwindle, the role of pesticides and herbicides are coming into sharper relief. In that respect, hemp has a natural advantage over other crops as it doesn’t require pesticides and fertilisers.
We have long heard of the health benefits of hemp-derived products such as cannabidiol oil (or CBD oil), but pretty much the whole plant can be used. Its seeds are rich in omega-3, omega-6, and fatty acids, and help fend heart problems.
As mentioned above, the fibrous part of the plant sequesters carbon and produces low-carbon materials for construction, while its roots are used to treat joint pain and for deep tissue healing.
And then we have hemp for bioethanol production and even hemp seed veggie burgers. The list goes on; so, there are many ways for farmers to make money from it.
>> What can be done to make our soils healthier? Take a look at our blog on solving soil degradation.
Hemp has excellent insulation properties.
I bet you know at least one person with a bamboo t-shirt or socks. Hemp has similar textile potential to its super material cousin. As the fashion industry interrogates its wayward past, the pressure will increase to lighten the footprint of clothing materials. Estimates vary, but hemp is said to need less than half the water required to cultivate and process than cotton textiles and its toughness is handy in long-lasting carpeting.
Hemp has been heralded as a wonder material for decades but there is that elephant in the room. The restricted uses of hemp-related materials curb the extent to which it can be grown in the UK. At the event, delegates noted that outdated legislation, lack of government support, and education are among the factors holding back the growth of hemp on an industrial scale.
And yet, there is growing demand for natural materials that tackle climate change, especially those that sequester carbon. With pension funds increasingly divesting from fossil fuels, and the ever growing importance of corporate sustainability in business, sustainable materials such as hemp are now more attractive.
Arguably the most exciting contribution of the day was the mention of zero-cannabinoid industrial hemp. Even though the THC content levels present in hemp are low (compared to the high levels found in marijuana) and it’s unattractive as a THC source, hemp is still very strictly regulated in the UK compared to North America and the rest of the EU.
One participant mentioned that hemp genes could be edited to remove the cannabinoid – and, if that were to be achieved, it could change everything. Then we would really see hemp happening in the UK.
>> Interested in more events like this one? Visit our Events pages.
We caught a tantalising glimpse of the next generation wearable technology at this year’s Bright SCIdea challenge final.
When we look at our FitBits or Apple Watches, we wonder what they could possibly monitor next. We know the fluctuations of our heartbeat, how a few glasses of wine affect our quality of sleep, and the calories burnt during that run in the park. But what’s next?
If the amazing wearable devices pitched by just three of our Bright SCIdea finalists are anything to go by, then we can look forward to not just next generation health monitoring but possible in-situ treatment too.
In recent times, medics have learnt far more about stress and its effect on our health. Indeed, stress was the focus of Happy BioPatch (from Oxford University and Manchester University) technology. The second place team has incorporated an IP-protected enzyme within a patch that measures your stress levels (by detecting the levels of cortisol in your sweat) throughout the day.
This information migrates from body to phone and notifies you if your stress levels are too high. One of many exciting aspects of this technology is that it could be used by physicians to check if patients need treatment for depression and prevent the serious consequences of stress. As one of the judges said, ‘I like it because it’s preventative.’
From mental health to physical health, two of the other finalists use wearable devices to address maladies in in-situ. BioTech Inov, from the University of Coimbra in Portugal, has developed plans for a subcutaneous biomedical device that tracks the blood sugar levels in diabetes patients. This technology would enable the wearer to track their blood sugar levels and let them know if trouble is lurking.
The latest smart watches track your body temperature, sleep quality, and can even detect electrodermal activity on your skin to gauge stress levels. | Editorial image credit: Kanut Photo / Shutterstock
Another intriguing development was the in-device treatment developed by the Hatton Cross team (comprising students from the University of Warwick, Imperial College London and Queen Mary University of London). The team is developing wearable technology that can detect wrist pain from sport, or the types of repetitive stress injuries arising from typing or writing too much.
One of the most fascinating aspects of the technology is the potential for in-device treatment. On the preventative side, the device could use vibration to alert users that their wrists are under strain. They also mentioned using heat from the device, or the release of a 0.05 Tesla magnetic field, to relax the muscles.
Another really insightful comment on the technology came from one of the judges. Dr Sarah Skerratt suggested that this type of technology - which is subtly attuned to the movements of the hand and wrist - could theoretically be used in the early diagnosis of Parkinson’s disease or Alzheimer’s disease. That is not to say there aren’t regulatory issues with developing wearable technologies for medical purposes, as the judges pointed out, but the potential of such devices is huge.
Wearable devices could be used to help diabetes sufferers, such as this Insulin Management System used by those with type 1 diabetes. | Editorial image credit: Maria Wan / Shutterstock
The staggering thing is that the technologies pitched by the Bright SCIdea finalists are just three of the myriad innovations being developed around the world at the moment.
Thirty years ago, few of us could have imagined that we would have a personal computer, music system, TV, watch, video, phone, camera, and games console all encapsulated within a single box that fits in our pockets. In 30 years’ time, we will scarcely be able to believe the health capabilities of the devices worn on our wrists and bodies.
Perhaps you will have heard of them first during the Bright SCIdea challenge?
From learning what appeals to investors and increasing the public’s awareness of your products, there are huge benefits to be gained from winning competitions such as Bright SCIdea. So, how can you benefit from entering and what’s in store from this year’s shortlisted teams?
There was a fine article recently in Nature that crystallised the many benefits of entering science competitions, which extend far beyond the coveted prize money.
Winning the competition can take your product from obscurity into the eyes and minds of the public. Importantly, winning immediately gives your innovation credibility as your product (and your vision for it) will inevitably have been vetted by a team of expert judges.
You will also gain valuable publicity. Not only will the organisers promote these innovations, the new-found exposure will increase traffic to your own website and social channels.
Another really important facet of these competitions is that they help develop business sense in line with scientific innovation. In the aforementioned Nature piece, Ulrich Betz, Vice-president of Innovation at Merck, said: ‘Joining competitions can be a useful way for researcher-entrepreneurs to learn what appeals to investors and companies — training that many academic researchers lack… Participants have told me they’ve become more confident working in science and business after taking part.’
Indeed, this tallies with the experiences of last year’s BrightSCIdea winners, Metallogen. The team developed a novel nanoparticle spray that assists the natural process of phytoremediation to extract rare metals from mining. These metals can be sold on the market while decontaminating land next to mining sites at the same time.
Last year’s Bright SCIdea winners used a novel approach to boost metal recovery on old mining sites and decontaminate the land.
However, having an ingenious idea is one thing. Bringing it to market is another. And this is where the training for all the shortlisted teams helped. Metallogen’s John O’Sullivan and Rafael Hunt-Stokes said: ‘The competition has also taught us how to carry out market research and put together a cogent business plan, with the pitching training giving us the ability to convey our business idea in a compelling manner to investors and other stakeholders.’
>> Inspired by Metallogen’s success at Bright SCIdea? Read more about them in our news article.
So, from network building to training and advice on key areas such as intellectual property, these competitions can sharpen your innovations and bring them to that all-important next stage. That’s exactly what the shortlisted teams for this year’s BrightSCIdea plan to do.
This year’s entrants have certainly taken it upon themselves to tackle some of society’s grandest challenges. The Eolic Wall team, hailing all the way from the National University of Engineering in Peru and Universidade Estadual Paulista in Brazil, has created a wind energy system to help in our low-carbon energy transition. The Unmasked team (from the University of Durham) is also seeking to address the UK energy crisis while tackling waste by producing insulation materials from disposable face masks.
In health, the BioTech Inov (University of Coimbra, Portugal) team has entered a ‘highly efficient and versatile nanotechnological subcutaneous biomedical device with a high lifespan’, and the Hatton Cross team (from University of Warwick, QMUL, and Imperial College, London) has also submitted a wearable device that aims to enhance the wearer’s quality of life.
In an effort to address mental wellbeing, the Happy BioPatch team (from Oxford University and Manchester University) has created ‘a wearable gadget which continuously monitors cortisol levels aiming to prevent serious consequences as a result of stress’. Finally, the CardiaTec team (from the University of Cambridge) is specialising in tackling cardiovascular disease.
There’s so much to be gained from being part of competitions such as BrightSCIdea. We can’t wait to hear from the leaders of tomorrow.
Who knows? Maybe this will be the first you hear from a future Nobel prize winner?
>> Keep an eye out on Twitter for all of the wonderful innovations in this year’s BrightSCIdea competition at: @SCIupdate.
Why do we ignore climate change and what can we do about it? That’s what Toby Park, of The Behavioural Insights Team, explained in our latest SCItalk. Eoin Redahan reports.
Do any of these describe you?
A.I recycle whenever I can, but fly twice a year.
B.I switched to a renewable energy provider, but still drive to work twice a week.
C.I make sure all unnecessary lights are switched off in the house, but eat beef occasionally
D.I plan to live a greener lifestyle, but the real difference will be made at government level.
When it comes to climate change, most of us are full of good intentions. We want to do the right thing but when change becomes too difficult or inconvenient, people (like me) lapse into old habits. In his excellent talk, why we ignore climate change and what we can do about it, Toby Park explained these contradictions and outlined how ‘nudge’ behaviour can be used to tweak our habits.
Fundamentally, Park argued that most people mean well. After surveying a couple of thousand people in the lead-up to COP26, the Behavioural Insights Team found that 67% of respondents planned to take at least five new actions to tackle climate change and 99% said they would take at least one.
So, why then do we ignore climate change en masse? ‘We are like swimmers in a stream,’ Park said. ‘We have the opportunity to swim in one direction or another but we are in a stream that has a current.’
We’re good at recycling but not as resolute when it comes to taking fewer flights.
Life is hard enough. We tend to do what is easy and affordable, but there are other reasons why we’re not falling over each other to buy electric vehicles or driving to the south of Spain for our holidays instead of flying.
The first is psychological distance. For many people, the prospect of climate change is too distant to take seriously. Unless you have woken up to find your kitchen submerged by flooding, its effects may seem far away; yet, the changes we must make are in the present.
The problem is, it’s sometimes hard to act when you cannot feel the urgency. So, people find it hard to frontload the hardship, as they see it. Park likened it to being told that you must have the hangover before you go drinking – and how many of us would choose that?
Second, we are experts at fooling ourselves. As Park noted, we’re all natural storytellers when it comes to crafting positive images of ourselves. We are the masters of cognitive dissonance. On the one hand we feel virtuous when we recycle paper, plastic, and food scraps, yet we’ll hop on a plane for that wedding in Dublin.
‘We all have the tension of what’s in our own self interest and what’s altruistic or pro-social,’ Park said, adding a Robert Heinlein quote that encapsulates the human condition. ‘Man is not a rational animal,’ he said. Man is a rationalising animal.’
A third reason why we ignore climate change, according to Park, is that our actions rarely benefit us personally. If you buy an electric vehicle, the price of that new Tesla will sting and you’re not going to benefit from the carbon emissions saved. However, if there is collective action, everyone would benefit from cheaper electric vehicles to less filthy air.
So, what can we do about climate change?
As was mentioned above, one of the foci of the Behavioural Insights Team is encouraging ‘nudge’ behaviour – what Park described as softly encouraging a certain type of behaviour without restricting choice. And it turns out, there are lots of ways to nudge us well-intentioned, self-centred creatures into healthier habit.
Examples of nudge behaviour are everywhere. In Switzerland, energy companies made green energy the default choice and people – out of either convenience or conscience – tended to stick with this option. Park mentioned how one canteen reduced food waste by up to 40% through the introduction of a small friction: removing the plastic trays (Thiagarajah and Getty 2013). In a similar sphere, he said Sainsbury’s Cafe increased orders of its plant-based meal options by calling items ‘field-grown’ rather than ‘meat-free’ or ‘plant-based’.
Park mentioned that we can motivate different behaviour by introducing a social element. He noted that solar panels were found to be socially contagious in California and parts of Europe, while the same has happened in the UK with the introduction of green number plates for electric vehicles.
Comparing people to their peers is another useful way of changing habits for the better. Benchmarking people’s behaviour against the norm – such as telling someone they use more energy than most customers – is one way of doing it. Publishing environmental performance league tables for organisations is another to encourage a climate-friendly approach.
If you don’t think these sorts of nudge behaviours don’t work, think of the humble plastic bag tax. When you take your own bags for your weekly shop, you might save just 30p on a £30 shop. But have you done it? And are you doing it still?
Unfortunately, there is no dancing around the fact that 60% of emissions reduction requires behaviour change, according to Park. So, nudge behaviour will help but we’ll be needing more power behind that elbow.
What’s in a name? Language can have a profound effect on our choices. Now, who’s for a field-grown breakfast?
‘Small nudges aren’t enough,’ he said. ‘We also need to apply this lens to systemic, transformative change. That means finding smart ways to tilt the functioning of markets.
He said that consistent, long-term decision making is not only important for individuals but for businesses too.
‘Incentives are massively important for corporations,’ he added. ‘That would generally be my first port of call. That’s where the bigger impacts can be found.’
At the end of the talk, a member of the audience asked Park, simply, if there was hope? To answer that, he offered the example of plant-based food.
Not so long ago, many plant-based meat alternatives were the preserve of the few. However, consumer interest in plant-based foods has ‘mushroomed’ in recent years and retailers have responded with a swath of new food products.
‘Change can be runaway and self accelerating, Park said, ‘and we shouldn’t forget that solutions can scale exponentially… New norms can, all of a sudden, spread very quickly.’
>> To listen to Toby’s talk, go to YouTube
The clichés we use become so downtrodden that we often say them without thinking. How many times, for example, have you said you went with your gut on a certain decision?
As with many of these aphorisms, there appears to be genuine wisdom behind it. Scientists are learning all the time about the links between our guts and our brains, and recent findings from a California Institute of Technology-led (Caltech) study have added to our understanding of what’s going on behind our belly buttons.
This research contends that a particular molecule, produced by our gut bacteria, has contributed to anxious behaviour in mice. The Caltech researchers say that a small-molecule metabolite that lives in the mouse’s gut can travel up to the brain and alter the function of its cells. This adds further grist to the belief that there is a link between our microbiome, brain function, and mood.
The researchers behind the Nature paper say previous studies found that people with certain neurological conditions have different gut bacteria communities. Furthermore, studies in mice revealed that manipulating these communities can alter neurological states.
>> Curious about which herbs could boost your wellbeing and how they work in your body? Then read our recent blog on this topic.
Their study investigated the bacterial metabolite 4-ethylphenyl sulphate (4EPS) that is produced in the intestines of humans and mice and circulates throughout the body. In particular, they focused on the effect of 4EPS on mouse anxiety. For the sake of the study, mouse anxiety measured the creature’s behaviour in a new space - whether it hid in a new space as if from a predator or whether it was willing to sniff around and explore it.
The researchers compared two groups of lab mice: those colonised with pairs of bacteria that were genetically engineered to produce 4EPS, and a second group that was colonised with similar bacteria that couldn’t produce 4EPS. They then observed the rodents’ behaviour after being introduced to a new area.
Some mice become anxious when introduced to new spaces, and this is reflected both in the gut and the brain.
The results were very interesting indeed. The researchers observed that the group of mice with 4EPS spent far less time exploring this new place and more time hiding compared to the second group of non-4EPS mice. They also found that brain regions associated with fear and anxiety were more activated within this first group.
>> Interested in drug discovery? Why not attend our upcoming event at the Francis Crick Institute, London, UK.
When the mice were treated with a drug that could overpower the negative effects of 4EPS, their behaviour became less anxious. A similar study in Nature Medicine also found that mice were less anxious when treated with an oral drug that soaked up and removed 4EPS from their bodies.
The Caltech-led research could inform our understanding of anxiety and mood conditions.
‘It’s an exciting proof-of-concept finding that a specific microbial metabolite alters the activity of brain cells and complex behaviours in mice, but how this is happening remains unknown,’ says researcher Sarkis Mazmanian, in whose laboratory much of the research took place.
‘The basic framework for brain function includes integration of sensory and molecular cues from the periphery and even the environment. What we show here is similar in principle but with the discovery that the neuroactive molecule is of microbial origin. I believe this work has implications for human anxiety or other mood conditions.’
So, our predecessors were right: there’s a lot more to those gut feelings than you think.
>> Read the Nature paper on the Nature magazine website.
How well equipped is the UK’s battery supply chain to meet the growing demand for electric vehicles? We took a closer look to mark National Battery Day.
Main image editorial credit: Phaustov/Shutterstock
For many of us, it’s exciting to see the growth of the electric vehicle industry. Our personal transport will be cleaner. Our roads will be quieter. Indeed, from 2030 the UK government will ban the sale of pure internal combustion engine cars, and the widening role of ultra-low emission zones will hit many motorists in the pocket. Whether we like it or not, change is coming.
That does not mean we are prepared for it. As demand for electric and hybrid vehicles accelerates, and more stringent trade rules put pressure on having a local battery supply chain (stricter Rules of Origin for trade will come into force by 2027), the UK must get its complete supply chain up to speed.
For this to happen, chemists, suppliers, manufacturers, innovators, government representatives, and others need to make strides in several areas. Over the past year, a group of more than 50 participants at SCI’s Energising the UK Battery Supply Chain workshops have identified next generation technology, the scale-up of innovative technologies, the skills and knowledge base, and standards for materials testing as areas for improvement.
Brine pools for lithium mining. There is a global clamour for raw materials including lithium.
The UK also needs a consistent stream of key battery materials. It needs technologies that reduce the dependence on some of the current materials for hybrid and electric vehicles. It must integrate efficient battery recycling and manufacturing approaches to reduce its dependence on long-distance imports and much coveted raw materials such as lithium, nickel and cobalt.
It is a big challenge. As David Bott, SCI’s Head of Innovation (who helped run SCI’s five Energising the UK Battery Supply Chain workshops) said, there isn’t enough of a UK electric battery supply chain at the moment.
>> Find out what the experts thought about improving the UK battery supply chain in our Energising the UK Battery Supply Chain Part 5 video.
David did note that the UK Government (through UK Research and Innovation) has been investing in the scale-up of cell assembly through the Energy Innovation Centre at WMG (from 2012/3) and the UK Battery Industrialisation Centre (through UKRI and the Automotive Propulsion Centre). It will also support the construction of Britishvolt’s electric battery ‘gigafactory’ in Blyth, Northumberland.
However, he added that: ‘All of them, however, are talking about the assembly of the cells and 60% of the value is in the materials. We need a battery materials supply chain in the UK – not all the way back to mining, of course, but as much as we can.’
Recent developments in the UK have been heartening, but many more will be needed to create a viable battery supply chain.
Smoother collaboration is also required. ‘We need recognition that the UK needs more support for the chemistry part of the supply chain,’ he said. ‘We need a lot more collaboration – engineers need to understand that chemistry companies would engage more if they understood the size of the opportunity. The main thing we need at the moment is awareness of the opportunities.’
Despite the difficulties, green shoots have appeared recently. In late January, the government announced that it has backed Britishvolt’s aforementioned plans to build large volumes of electric vehicle batteries (through the Automotive Transformation Fund). According to the government, the factory will produce enough batteries for more than 300,000 vehicles a year and create 3,000 direct, highly-skilled skilled jobs. Britishvolt have also announced a partnership with Glencore to recycle battery materials.
>> Sign up for our next Energising the UK’s Battery Supply Chain workshop.
Oxford-based chemical products manufacturer Nexeon has secured US$80 million (about £59 million) in funding to scale up the production of its silicon anode materials. Finally, Sheffield-based sodium-ion battery technology company Faradion has been acquired by Indian conglomerate Reliance Industries for £100 million. A further £25 million will be invested as growth capital to accelerate the commercial rollout of its sodium-ion battery technology.
Faradion says that its sodium-ion technology provides ‘significant advantages compared to lithium-ion technology, including greater sustainability, a patented zero-volt safe transport and storage capability’.
So, there is some good news to celebrate as you gather around with your families to celebrate National Battery Day. The battery supply chain, unfortunately, must wait for another day.
What is the future of electric cars? Find out more in this Autotrader article.
Machine-made snow has made this Winter Olympics happen in Beijing, but at what cost?
If you take a look at the weather in Beijing right now, you’ll notice that it isn’t really that cold. You can enjoy daily highs of about 8°C in early February, which we’d be happy enough here in London.
These mild conditions have been a problem for the organisers of the Winter Olympics, which are currently taking place in Beijing and environs. Indeed, the distinct dearth of snow has meant that the Beijing Games have become the first to be run largely on artificial snow.
Snowmaking machines spray artificial snow on a ski slope during the FIS Ski Cross World Cup, a test event for the 2022 Winter Olympics
For some, the presence of 130 fan-driven snow generators and 300 snow-making guns spewing out machine-made snow represents a waste of resources, even if these machines are powered entirely by renewable energy.
In all, 49 million gallons of water will reportedly be used to make the Games possible. So, to say they are water-intensive is something of an understatement. However, the issues don’t end there. There is also an issue with the type of snow produced.
>> What can you do about climate change? Register for this free talk to find out more.
Some claim artificial snow creates more dangerous conditions for athletes.
According to the recent Slippery Slopes report written by the Sport Ecology Group (in conjunction with Loughborough University UK and Protect Our Winters UK), the composition of artificial snow can create dangerous conditions for the athletes. Basically, it creates a faster, harder surface that could result in more severe injuries.
The reason given for this is that artificial snow is almost 30% ice and 70% air, compared to natural snow, which is closer to 10% ice and 90% air. This ‘grittier ice-pack’ creates tougher conditions for athletes, many of whom travel at great speeds down steep slopes.
In the same report, former Winter Olympian Laura Donaldson explains why these machines create suboptimal snow. ‘The artificial snowflakes they generate have cylindrical structures (unlike the far more intricate structure of natural flakes),’ she said, ‘which mould together to form bulletproof ice conditions.’
Furthermore, this less permeable layer of ice may hinder the growth of vegetation, and the noise of the machines disrupts wildlife. In some resorts, chemicals are also added to create longer lasting snow.
At Beijing, the organisers claim not to have used chemicals in the snow-making process. However, others rely on machines and chemical-kind for a helping hand. According to the Sport Ecology Group report, a pesticide was used at the 2010 Games in Vancouver to allow the water to freeze at higher temperatures; and snow hardeners such as salt and fertiliser have been used to improve snow quality on cross-country skiing trails.
If hosting the Winter Olympics in an area without much snow seems crazy to you, it might not be quite as daft as you think. The bleak reality is that global warming is reducing the number of venues that can host this enormous event without artificial help.
According to an academic paper by Scott et. al. in 2014, only six of the last 19 Winter Olympics host cities will still have the climatic conditions to do so by the 2080s. Of course, that doesn’t take artificial snow into account.
So, when you see Qatar being awarded the 2050 Winter Games, don’t tell me you haven’t been warned.
Johnson Matthey has launched a technology to help create a green hydrogen-based aviation fuel, while the European Commission has approved a €900 million scheme (£750 million approximately) to support renewable hydrogen investments.
SCI Corporate Partner Johnson Matthey has developed HyCOgen to convert CO2 and green hydrogen into a scalable and sustainable aviation fuel (SAF). The speciality chemicals company says it has combined this Reverse Water Gas Shift technology with FT CANS Fischer Tropsch technology through a catalysed process. With this approach, the green hydrogen and CO2 are converted into carbon monoxide, which is combined with additional hydrogen to form syngas.
Integration with the FT CANS technology is used to turn 95% of the CO2 into a high quality synthetic crude oil. This synthetic crude oil can then be upgraded into sustainable, drop-in fuel products for aviation transport – a sector responsible for 12% of transport-related CO2 emissions, according to the Air Transport Action Group.
Green hydrogen fuel, produced using renewable energy, could help decarbonise the aviation industry.
Jane Toogood, Sector Chief Executive at Johnson Matthey, said: “Given the challenges associated with new propulsion technologies and airport infrastructure, plus the long asset life of aircraft, there are significant hurdles in moving from hydrocarbon-based aviation fuel to alternatives such as battery electric or hydrogen.
“By combining HyCOgen with FT CANS, we can now deliver customers a cost-efficient, reliable and scalable technology to help increase SAF production, backed by our track record of successful technology development and commercialisation.”
>> Concerned about climate change? Find out what you can do in this free webinar: https://www.soci.org/events/hq-events/2022/why-we-ignore-climate-change-and-what-we-can-do-about-it
In other hydrogen-related news, the global hydrogen industry has received a boost with the European Commission approving a €900 million German scheme to support investments in renewable hydrogen production in non-EU countries.
The aim of the H2Global project is to meet the growing EU demand for renewable hydrogen production, which is expected to increase significantly as EU countries reduce their reliance on fossil fuels. Even though the initiative will benefit EU countries, UK-based organisations concerned with hydrogen power could benefit from this investment.
>> Young chemists are getting creative in the fight against climate change. Read more in our COP26 review blog.
Margrethe Vestager, the European Commissioner for Competition who is in charge of competition policy, said: “This €900 million German scheme will support projects leading to substantial reductions in greenhouse emissions, in line with the EU’s environmental and climate objectives set out in the Green Deal.
“It will contribute to addressing the increasing demand for renewable hydrogen in the Union, by supporting the development of this important energy source in areas of the world where it is currently not exploited with a view to importing it and selling it in the EU. The design of the scheme will enable only the most cost effective projects to be supported, reducing costs for taxpayers and minimising possible distortions of competition.”
Greenhouse gas emissions statistics can be misleading. At a recent SCI webinar on the Future of Agriculture, the Agrisciences Committee put its finger on some glaring gaps in the figures.
If all of the cows in the world came together to form a country, that nation state would be the second highest emitter of greenhouse gas emissions in the world.
McKinsey Sustainability’s statistic was certainly startling. However, Agrisciences Group Chair Jeraime Griffith mentioned other equally striking figures in his wrapup of the social media discussion generated at COP26.
In his talk as part of the Agrisciences Committee’s COP26 – What does it mean for the future of agriculture? webinar on 7 December, Griffith also noted that:
On the face of it, these figures are sobering; yet, like many agriculture-related figures, they don’t tell the full story.
Insane in the methane
Kathryn Knight felt that agriculture received negative press at COP26 in relation to greenhouse gas emissions. ‘It doesn't seem to take into account carbon sequestration (capturing and storing atmospheric carbon dioxide),’ said the Research & Technology Manager of Crop Care at Croda. ‘Why isn’t that being brought into the equation when we’re talking about carbon and agriculture?’
Martin Collison expanded on this point. He emphasised the need to separate carbon emissions by system – such as extensively grazed livestock animals and those fed on grain – and to account for systems that sequester carbon in the soil. The co-founder of agricultural consultancy Collison & Associates also pointed out the problem with bundling all our greenhouse gases as one.
Greenhouse gas emissions are sometimes unhelpfully bundled together, instead of being separated by gas and agricultural system.
‘We count methane in the same way we emit carbon,’ he said. ‘When we emit carbon, it’s in the atmosphere for 1,000 years, but with methane it’s 12 years. The methane cycle is a lot, lot shorter.’
And the difficulties with the statistics don’t end there. For example, countries often announce impressive emission reductions without taking trade into account. This, of course, gives the figures a greener gloss.
‘To me, there's a need to be more up front with a lot of the data because agriculture and food are traded around the world,’ he added. ‘A lot of the emissions data ignore what we trade.
‘In the UK, we make big claims about how fast we’ve progressed with carbon emissions, but if you look at what we consume, the progress is much much slower. The things we produce less of, we import.’
>> SCI was at COP26 too! Read about the role of chemistry in creating a greener future.
Full of hot air?
Emissions trading also serves to blur the picture. For Jeraime Griffith it is an unsatisfactory solution. ‘In terms of carbon trading, we have cases where the higher emitters continue producing in the way they’ve always been producing,’ he said.
‘It doesn't bring in any restrictions on the amount of carbon they emit; it just shifts the problem somewhere else. I don't know how carbon trading benefits us getting to Net Zero. It just seems to be kicking the ball farther down the road.’
Is emissions trading part of the solution or part of the problem?
So, when you take into account 1. emissions trading, 2. the absence of food imports in data sets, 3. the bundling together of different greenhouse gases in emissions figures, and 4. the failure to take carbon sequestration into account, it’s clear that many of the statistics we receive are incomplete.
‘There’s lots of complexity behind the numbers and we tend to lump all of it together,’ Collison said. ‘There’s a need to go much much further.’
>> SCI’s Agrisciences Group is a unique multidisciplinary network covering the production, protection and utilisation of crops for food and non-food products. It has 250 members including academic and industry leaders, researchers, consultants, students, and retired members. If you’re interested in joining the group, go to: www.soci.org/interest-groups/agrisciences
How do you get large audiences to read about your work? Roger Highfield, Science Director of the Science Museum, and Steve Scott, Public Engagement Lead of UK Research and Innovation, shared their insights at a recent webinar organised by SCI.
‘When I talk to people about science writing – when I’m talking about the introduction – I ask them to practise on a long-suffering friend and read a couple of paragraphs of what they’ve written. If they reach for their phone, you’ve done something wrong.’
Some people’s observations should be taken with a liberal fistful of salt, but Roger Highfield is certainly worth listening to when it comes to connecting with the public. As Science Director of the Science Museum Group, he helped engage with more than five million visitors in 2019/20 alone and has written and edited thousands of articles as Science Editor of the Daily Telegraph and Editor of New Scientist.
Roger Highfield, Science Director of the Science Museum
So, how can you reach large audiences with scientific content? First of all, salience is important. How does what you’re talking about have a material effect on people’s lives? As Roger Highfield noted dryly: ‘People will be very interested in asteroids when one’s bearing down on the Earth.’
Similarly, the public has been voracious in its consumption of Covid-19-related content despite the complicated nature of the virus and vaccine development. During lockdown, Roger Highfield’s long form Q&A blogs about Covid-19 were hugely popular because, as he said, ‘there was a public appetite for a deeper dive into the science’.
Aside from writing in a way that decongests heavy, complicated subjects, it also helps to get your research in front of the right people, namely communications specialists. ‘One lesson for mass engagement is to work with media organisations,’ he added. ‘It’s more than a platform – you’re dealing with experts in public engagement.’
For larger organisations, citizen science is an excellent way to engage people by making them part of a project. The Great Backyard Bird Count is a fine example of citizen science at its simple, effective best, with thousands of bird-watchers helping provide a real-time snapshot of bird populations around the world.
Highfield has engaged with the public in all manner of citizen science initiatives, from recent online cognition tests in which 110,000 people took part, all the way back to an experiment asking people about the catchiest song in the world. ‘At the time, it was The Spice Girls’ Wannabe,’ he said. ‘People recognised it in 2.5 seconds.’
At its best, citizen science doesn’t just help you to engage people in your work; it can be used as a valuable way to gather information and provide unique perspectives. ‘Citizen science is not just a flash in the pan. The role is changing,’ said Steve Scott, Public Engagement Lead at UK Research and Innovation (UKRI). ‘It’s an effective way of gaining knowledge… bringing different forms of knowledge and expertise into research.’
Steve Scott, Public Engagement Lead of UK Research and Innovation
Scott used the University of West London-led Homes Under the Microscope project to illustrate his point. As part of this project, people in Bristol and Bradford will detect and monitor airborne microplastic sources in their homes and feed this information back to the project organisers to help assess the prevalence of these substances.
If you’d like more people to read about your research or product, it’s also worth thinking about the way people consume media. According to Scott, the general public tends to consume science through televisions and museums (for example, a visit to the zoo), and people are most likely to follow up on scientific matters having seen them on the news.
Many people learn about science through social media and YouTube, but other vehicles are worth considering too if you want to raise awareness. The UKRI views gaming as a significantly untapped area of public engagement and is investing in this area. Another intriguing way to raise awareness of innovative research is through awards, with the recent, well publicised Earthshot Awards providing a case in point. ‘They’ve taken research grants,’ Scott said, ‘and made them into the Oscars.’
Encouragingly, as the means of communication are changing, so too is the readiness of researchers to share their work. Both Highfield and Scott have seen a large shift over the past 15 years or so, with more and more scientists communicating their research. ‘It’s recognised as being an important part of being a researcher now,’ Scott said. ‘You’re excited about [your research]… Why would you not talk to the public about it?
So, what is the most important takeaway from the talks, apart from that all-important Spice Girls fact? Fundamentally, when you are communicating your research or peddling your company’s wares, it helps to narrow your focus.
Indeed, Scott reminded us that the public is not a homogeneous group. ‘If we want to engage with millions of people, we need to think of audiences as more than just the general public,’ he said.
He said that 75 per cent of the potential UK audience – roughly 49 million people – falls into one of two groups: they don’t think science is for them, or they’re inactive. So, it’s worth taking an in-depth look at your target demographic and the places it goes to for news before sharing your work.
Earlier, Roger Highfield emphasised the same thing. He said: ‘If there’s one thing I want you to take from this talk, it’s to think about the audience.’
>> Watch How to engage with millions of people in full on our YouTube channel at: https://youtu.be/HSOMQd958EQ
A group of inspiring young scientists took centre stage at COP26 on 4 November to show how the next generation of chemists is finding tangible climate change solutions.
In a day dominated by what countries pledged to stop doing at COP26, such as pursuing coal power and financing fossil fuel projects overseas, it was refreshing to learn about low-carbon technologies and the young people driving their development. At the Next Gen forum, we heard from an array of young chemists, all associated with SCI, who are at the sharp edge of this change.
We heard from Brett Parkinson, Senior Engineer of Low Carbon Fuels and Energy Technologist at C-Zero, who is working on commercialising a way to decarbonise natural gas. The California-based company’s technology converts the natural gas into hydrogen and solid carbon to provide a clean energy source while sequestering the carbon; and the aim is to have this process up and running next year.
Natasha Boulding is building towards Net Zero a different way – with a greener concrete. The CEO and Co-founder of Sphera has developed a lightweight carbon negative additive using waste plastics that aren’t currently being recycled. She says the company’s blocks are the same strength and price as existing concrete blocks, but with 30% more thermal insulation. There is also the added benefit of reusing waste materials that would otherwise have gone to landfill or been incinerated.
Another solution discussed by Dominic Smith, Process Development Engineer at GSK, reduces energy consumption through green chemistry. He is trying to find greener ways to make medicines using enzymes. These enzymes, which can be found in plants and soil, replace chemical synthesis steps to cut energy consumption during processing and reduce hazardous waste.
Panel (left to right): Dominic Smith, Natasha Boulding, Clare Rodseth, Jake Coole, Nikita Patel, and Oliver Ring (Brett Parkinson spoke via video link).
It was apparent from the discussion that many solutions will be needed for us to reach our climate change targets. On the one hand, Jake Coole, Senior Chemist in Johnson Matthey’s Fuel Cells team, is working on membrane electrode assembly for hydrogen fuel cells to help us transition to hydrogen-powered buses and trucks.
At the same time, Clare Rodseth, an Environmental Sustainability Scientist at Unilever, has been using lifecycle assessments to reduce the environmental impact of some of the 400 Unilever brands people use all over the world every day. For example, this work has helped the company move away from petrochemical ingredients in its home care products. ‘Even small changes,’ she said, ‘have the potential to bring about large-scale change.’
However, for each of the technologies discussed, barriers remain. For Coole and co., having a readily available supply of hydrogen and charging infrastructure will be key. And for Dominic Smith and his colleagues, the use of enzymes in green chemistry is still in its infancy; and getting enzymes that are fast enough, stable enough, and produce the right yield is difficult. Nevertheless, he noted that manufacturers are now using enzymes to produce the drug amoxicillin, reducing the carbon footprint by about 25%
And some things will take time to change. Natasha Boulding noted that concrete is the second most used material in the world after drinking water, and we simply can’t create many green technologies, such as wind turbines, without concrete foundations.
She said the construction industry is quite traditional but also pointed to perceptible change, with the green concrete market growing and companies becoming increasingly aware of their carbon footprints.
Collaboration was seen as crucial in producing climate change solutions.
The reality is that global action on climate change is recent. As Brett Parkinson said: ‘the main reason we’re talking about it now is that there’s a driver to do it. Until the last decade, the world hadn’t cared about CO2 emissions. They just talked about caring about it.’
How pivotal is science in all of this?
So, what could be done to make climate action more effective? For Parkinson, effective policy is key. He argued that if the market isn’t led by policies that encourage low-carbon innovations, then it won’t work as needed. ‘It all starts with effective decarbonisation policy,’ he said. ‘Legacy industries are very resistant to change. If you don’t have strong and consistent policies… then they’re not going to adapt.’
Another key to our low-carbon evolution is collaboration, and the SCI provides a confluence point for those in industry and academia to work together to produce innovative, low-carbon products. As Clare Rodseth said: ‘Collaboration is really important – linking up people who can actually come together and address these problems.’
As the discussion came to a close, you had the impression that the debate could have gone on for much longer. ‘Hopefully, we’ve demonstrated that there is action, and it’s being driven by young people like our panellists today,’ summarised Oliver Ring, the event’s co-Chair, before asking for the result of the audience poll.
The question: How many of those watching believed that science is pivotal in providing climate change solutions?
The answer: Just the 100%.
>> Thank you to Johnson Matthey for sponsoring the event, to the speakers for sharing their time and expertise, and to co-chairs Nikita Patel and Oliver Ring for doing such an excellent job.
This Thursday at COP26, an inspiring panel of young scientists will discuss innovations that will help us mitigate climate change. So, what can we expect?
Millions of young people are frustrated by climate change inaction. Indeed, according to a University of Bath study, 60% of the next generation feel overwhelmed by climate anxiety. Often, the proposed solutions seem vague and intangible – well-intentioned ideas that drift away when the political winds shift.
And yet, when you see the ingenuity of young scientists, business people, and activists, it’s hard not to be excited. Undoubtedly, politics and our legal system will play a huge role in the drive to reach Net Zero, but arguably science will play the biggest role in transforming the way we live. Just think of the falling cost of generating solar power, improvements in battery chemistry for electric vehicles, the development of sustainable construction materials, and the rapid rollout of Covid-19 vaccines.
This Thursday at COP26, SCI will host the Next Gen youth forum event where the panellists discuss the climate change solutions they are working on right now and how they are being applied by industry. In the Countdown to Planet Zero roundtable, these scientists – drawn from within SCI’s innovation community – will explain their work to a global audience and the impact it will have on climate change.
They will discuss innovation in three key areas: topics of fuels of the future, turning waste into gold, and engineering nature.
The next generation has mobilised and is creating solutions to help avoid climate change disaster.
The panel will be chaired by two very capable young scientists. Oliver Ring is Senior Scientist at AstraZeneca’s large-scale synthesis team and Chair of SCI’s Young Chemists’ Panel, and passionate climate advocate Nikita Patel is a PhD student at Queen Mary University of London’s Centre of Translational Medicine and Therapeutics and STEM Ambassador for schools.
The other panel members include Clare Rodseth, of Unilever’s Environmental Sustainability Science team, who brings lifecycle analysis to product innovation to make products more sustainable.
Jake Coole, Senior Chemist in Johnson Matthey’s Fuel Cells team, is involved in the scale-up of new processes and next generation manufacturing, and Dominic Smith, Process Development Engineer at GSK, who is interested in engineering biology to create sustainable manufacturing processes.
Also present will be Dr Brett Parkinson, Senior Engineer of Low Carbon Fuels and Energy Technologist at C-Zero – a California-based startup that works on the decarbonisation of natural gas. In 2019, Brett was awarded an SCI scholarship for his research.
The lineup also includes Dr Natasha Boulding, CEO and Co-founder of Sphera Limited, a speciality materials company that has created carbon negative concrete blocks made from aggregate including waste plastic. According to Natasha, whose company also won SCI’s Bright SCIdea challenge in 2019: “In terms of combating climate change, interdisciplinary collaboration is the key. No one discipline has the answer to solve our biggest challenges – but together diverse minds can.’
>> Would you like to take part in BrightSCIdea and be in with the chance of winning £5,000? Be part of it.
Watch the event online
SCI is proud to be associated with these enterprising young scientists and the imaginative solutions they are developing to mitigate the effects of climate change.
‘As a global innovation hub, SCI wants to show how the next generation of scientists is actively developing solutions,’ said Sharon Todd, SCI CEO.
Sharon Todd, SCI CEO
‘Our COP26 youth forum debate will profile the work of young scientists and entrepreneurs addressing climate change in their work. This next generation of innovators has the power to change our world’s tomorrow.’
If you’d like to see the climate change solutions of tomorrow, register to watch the virtual event here.
To celebrate Black History Month, we take a look back at some of the great Black scientists and innovators. From laser eye surgery to the gas mask, here are some of the seminal contributions made by these ingenious inventors.
 Lewis Howard Latimer – Image credit: Unknown author Unknown author, Public domain, via Wikimedia Commons
 Leonidas Berry - Image credit: Adundi, CC BY-SA 4.0, https://creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons
 Betty Harris – Image credit: https://www.blackpast.org/african-american-history/harris-betty-wright-1940/ - Fair use image
 Patricia Bath - Image credit: National Library of Medicine, Public domain, via Wikimedia Commons
 Philip Emeagwali - Image credit: SakaMese, CC BY-SA 4.0, https://creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons
1880 – Johnson Powell
Have you ever used eye protectors to protect yourself against the glare of intense light? For those working in extreme environments such as fires and furnaces, Johnson Powell’s eye protectors will have been a sight for sore eyes.
1881 – James Wormley
James Wormley invented a life-saving apparatus for boats. His contraption included a string of floats that extended from a ship’s side via a sliding rod with projecting arms. The famous hotelier was also said to be at President Abraham Lincoln’s bedside when he died.
Image Credit: Unknown author, Public domain, via Wikimedia Commons
1882 – Lewis Howard Latimer
Lewis Howard Latimer is probably best known for inventing a durable carbon filament that was key to the success of the electric light bulb. Latimer also invented an evaporative air conditioner and even drafted the drawings to secure the patent for Alexander Graham Bell’s little known invention… the telephone.
>> Click here for more on Lewis Howard Latimer’s extraordinary contribution to science.
1912 – Garrett Morgan
Imagine using your own invention to save people’s lives? That’s exactly what Garrett Morgan did when he donned his patented smoke hood to rescue trapped men from a smoke-filled tunnel beneath Lake Erie. Morgan’s device later evolved into a gas mask, and he also invented a three-position traffic signal, hair straightening cream, and a self-extinguishing cigarette for good measure.
1916 – Madeline M. Turner
Madeline M. Turner’s ingenious invention was the fruit of her own frustration. Turner grew tired of squeezing oranges for her glass of juice, so she created the fruit press machine to solve the problem.
1932 – Richard Spikes
It’s safe to say Richard Spikes was a polymath. The American inventor created an automatic gear shift device for cars, a pressurised beer tap, and a horizontally swinging barber’s chair – all while working as a teacher and barber and being a capable pianist and violinist.
Image Credit: Adundi, CC BY-SA 4.0, via Wikimedia Commons
1966 – Leonidas Berry
This doctor and civil rights advocate invented the Eder-Berry gastroscopy endoscope in 1955, which helped doctors to biopsy the inside of the stomach without surgery. According to the US National Library of Medicine, ‘the Eder-Berry biopsy attachment made the gastroscope the first direct-vision suction instrument used for taking tissue samples during gastroscopic examination’.
Image Credit: https://www.blackpast.org/african-american-history/harris-betty-wright-1940/ - fair use image
1984 – Betty Harris
Perhaps the most explosive discovery of all belongs to Betty Harris. Harris’ spot test for detecting 1,3,5-triamino-2,4,6-trinitrobenzene in the field is used by US Homeland Security today to check for nitroaromatic explosives. In her spare time, Harris has even found the time to work with the Girl Scouts to develop a badge based on Chemistry.
>> SCI is proud to support #BlackinChem. Take a look at some of our recent work.
Image Credit: National Library of Medicine, Public domain, via Wikimedia Commons
1988 – Patricia Bath
Patricia Bath has helped return the gift of sight to thousands of people. The US ophthalmologist invented a quick and painless device that dissolves cataracts with a laser and cleans the eye, enabling the simple insertion of a new lens. Her laserphaco probe is still in use today.
Image Credit: Philip Emeagwali - SakaMese, CC BY-SA 4.0, via Wikimedia Commons
1989 – Philip Emeagwali
Nigerian computer scientist Philip Emeagwali won the prestigious1989 Gordon Bell Prize in Price Performance for a high-performance computer application that used computational fluid dynamics in oil-reservoir modelling. In the same year, Emeagwali also claimed to perform the world’s fastest computation – 3.1 billion calculations per second – using just the power of the internet.
2002 – Donald K. Jones
Donald K Jones made a notable contribution to medicine with his invention of a detachable balloon embolisation device that reduces the size of aneurysms (bulges in blood vessels). The endovascular occlusion device is implanted into the body, whereupon its clever balloon system and adhesive materials reduce the size of aneurysms.
>> Which barriers still block the way for Black chemists? Read Claudio Lourenco’s story.
We need to create more diverse paths into research and scientific innovation. Professor Dame Ottoline Leyser, Chief Executive of UK Research and Innovation, explains how industry clusters and a change of mindset could help.
What do you picture when someone mentions a chemist? Maybe you see someone like you working in a lab or office with your colleagues.
But what do people at the bus stop think? What would a secondary school student say? Do they see someone like them – or do they imagine an Einstein-like figure hidden away in a dark room with crazed hair and test tubes?
One of the most interesting messages from Professor Dame Ottoline Leyser’s Fuelling the Future: science, society and the research and innovation system talk on 29 September was the need to make sure science and technology are seen as viable careers for people throughout society.
Prof Dame Ottoline Leyser
You don’t need to be a genius to work in research and innovation. You don’t necessarily need to be a specialist, and you certainly don’t need to be hunched over a microscope with a jumble of figures and formulae on a board behind you. An array of different people, technical and non-technical, are needed to make the sector thrive.
Part of Dame Ottoline’s job as Chief Executive of UK Research and Innovation (UKRI) is to improve access to these sectors and to make sure that great ideas aren’t lost due to daunting entry barriers.
‘It’s a huge challenge,’ she said. ‘A large part of the challenge is the narrow concept that we all have of what a researcher and innovator look like.’
Leyser spoke about the need to create diverse routes through the system rather than squeezing everyone through the same narrow path. ‘The assessment criteria we use for individuals have become narrower and narrower,’ she added. ‘Some of it, ironically, is to make the system fairer, but objectivity in creativity is a total pipe dream. You end up crushing creativity by narrowing the criteria.’
She noted that those with mixed careers – interwoven with varied experiences – are to be welcomed. ‘That’s nothing to do with compromising excellence,’ she said. ‘Real excellence comes in multiple forms.’
>> Would you like to attend more talks like this one? Check out our Events page.
However, Leyser also spoke of the need to level up the UK from a productivity perspective. One way to do this is through smart specialisation and industry clusters. She mentioned Lincoln as an area where this approach worked well. Lincoln is home to extensive agriculture and the multinational technology corporation Siemens. As such, it made sense to help make it a centre for agricultural robotics.
UKRI is investing heavily in research and innovation into Net Zero energy solutions.
As the largest public funder of research and innovation in the UK, UKRI has a major role to play in funding such industry clusters and intelligent innovation. It has funded more than 54,000 researchers and innovators, and UKRI grants have generated almost 900 spinouts since 2004.
These include Oxford Nanopore, a biotech company whose DNA sequencing technology is now valued at £2.5bn. It has also cast an eye on the future, including delivering more than £1bn in R&D relevant to Artificial Intelligence and in excess of £1bn towards Net Zero energy solutions.
Leyser noted that the UKRI’s goal is to embed research and innovation more broadly across society – for it to be ‘by the people and for the people, rather than the exclusive domain of the privileged few’.
It is a grand challenge, but such sentiments are certainly encouraging.
SCI’s America International group has awarded the 2021 Perkin Medal to Dr Jane Frommer. The 114th Perkin Medal was presented to Jane at the Bellevue Hotel in Philadelphia, Pennsylvania, in recognition of her outstanding contribution to chemistry.
Dr Jane Frommer
Dr Frommer is renowned for her key contributions in electronically conducting polymers and scanning probe instrumentation. Her pioneering work with scanning probes paved the way for their use in chemistry, materials science and, eventually, in nanotechnology. According to SCI America, her nanoscopic analytic methods are vital to nanostructural research and are used across many industries.
Dr Frommer began her career in 1980 at Allied Corporate Laboratories (now Honeywell), where she created the solution state of electronically conducting organic polymers. In 1986, she joined IBM where, along with other instrumentalists, she demonstrated the ability to image and manipulate single molecules using scanning tunnelling microscopy. During her multi-year assignment at the University of Basel Physics Institute in the early 1990s, Dr Frommer’s team expanded the capability of scanning probes in measuring the functional properties of organic thin films with atomic force microscopy.
Since 2018, she has worked as a science advisor for Google. In this capacity, she has sought to increase the amount of open source data available in the physical and life sciences. She also helps Silicon Valley start-ups navigate the chemical and material challenges of nanotechnology and has mentored countless students and young scientists in high school, college, and in her laboratory in recent decades.
Previous recipients of the Perkin medal include Barbara Haviland Minor, of the Chemours Company, and Ann E Weber, of Kallyope Inc.
Dr Frommer has written more than 100 referred publications and is the co-inventor of more than 50 issued patents. With her extraordinary body of work spanning more than 40 years, she is a worthy recipient of the prestigious Perkin Medal.
The Perkin Medal is widely acknowledged as the highest honour in American industrial chemistry. It was established to commemorate the 50th anniversary of William Henry Perkin’s discovery of mauveine at the age of just 18. Perkin’s creation of mauveine, the world’s first synthetic aniline dye, revolutionised chemistry and opened up new frontiers in textiles, clothing, and other industries. Perkin was a founding member of SCI and this Medal was first presented to him in New York in 1906.
For more information on the Perkin Medal and the nomination process, visit: soci.org/awards/medals/perkin-medal
The War on Plastic is a grand title. To most of us, it doesn’t seem like much of a war at all – more like a series of skirmishes. Nevertheless, if you look closely, you’ll see that a lot of companies are tackling the issue.
GSK Consumer Healthcare (GSKCH) is one such organisation. The healthcare brand that gave us Sensodyne and Advil has launched a carbon neutral toothbrush to reduce our reliance on fossil fuels (which create virgin plastic).
The composition of its Dr. Best tooth scrubber is interesting. The handle comprises a mixture of a cellulose derived from pine, spruce, and birch trees and tall oil, which comes from the wood pulping industry. The bristles are made from castor oil and the plastic-free packaging includes a cellulose window.
According to GSKCH, Dr. Best is Germany’s favourite toothbrush brand and there are plans to apply the technology to toothbrushes across its portfolio, including its Sensodyne brand. At the moment, GSK needs to apply carbon offsetting initiatives to make the toothbrush carbon neutral, but it says it is working on future solutions that do not require this approach.
GSK isn’t the only company that is actively reducing the use of plastics and minimising waste. Supermarket chain Morrisons has made aggressive moves in recent years to cut waste, and has just launched six ‘net zero waste’ stores in Edinburgh that will operate with zero waste by 2025.
Customers at these stores will be able to bring back hard-to-recycle plastics such as food wrappers, foils, yoghurt tubs, mixed material crisp tubes, coffee tubs, batteries, and plant pots. At the same time, all store waste will be collected by a range of specialist waste partners for recycling within the UK, and unsold food will be offered to customers at a cheaper price on the Too Good to Go app.
Morrisons’ proactive approach will help find a new life for hard-to-recycle packaging.
‘We’re not going to reach our ambitious targets through incremental improvements alone,’ said Jamie Winter, Sustainability Procurement Director at Morrisons. ‘Sometimes you need to take giant steps and we believe that waste is one of those areas. We believe that we can, at a stroke, enable these trial stores to move from recycling around 27% of their general waste to over 84% and with a clear line of sight to 100%.
‘We all need to see waste as a resource to be repurposed and reused. The technology, creativity and will exists – it’s a question of harnessing the right process for the right type of waste and executing it well.’
If this approach is successful, Morrisons plans to roll out the zero waste store format in all of its 498 stores across the UK next year.
>> Interested in reading more about sustainability and the environment? Check out our blog archive.
The government has also issued its latest battle cry in the war on plastics. Having defeated plastic straws, stirrers and cotton buds, it has turned its attention to other single-use plastics.
Single-use plastic plates, cutlery and polystyrene cups are among the items that could be banned in England following public consultation.
The humble cotton bud has now been retired from active service.
Somewhat surprisingly, it estimates that each person in England uses 18 single-use plastic plates and 37 single-use plastic items of cutlery each year; so, it has begun moves to cut out this waste stream.
Environment Secretary George Eustice said: “We have made progress to turn the tide on plastic, banning the supply of plastic straws, stirrers and cotton buds, while our carrier bag charge has cut sales by 95% in the main supermarkets. Now we are looking to go a step further as we build back greener.”
All in all, it’s encouraging to see that companies and the government are brushing up on their sustainable practices.
>> Curious to find out what the future looks like for lab-processed food and meat alternatives? Read what the experts say here.
If you’re a vegan, do you really want to eat a ruby-red slab of plant protein that looks like lamb? If you are a health obsessive, would you opt for an ultra-processed, plant-based product if you knew it didn’t contain many vitamins and micro-nutrients? And why, oh why, are we so obsessed with recreating the taste and appearance of the humble hamburger?
These questions and more were posed by Dr David Baines in the recent ‘No meat and two veg – the chemistry challenges facing the flavouring of vegan foods’ webinar organised by SCI’s Food Group. The flavourist, who owns his own food consultancy and is visiting Professor at the University of Reading, painted a vivid picture of our changing culinary landscape – one in which 79% of Millennials regularly eat meat alternatives.
And this shift in diet isn’t just the preserve of the young. According to Dr Baines, 54% of Americans and 39% of Chinese people have included more plant-based foods and less meat in their diets. Furthermore, 75% of Baby Boomers – those born between 1946 and 1964 – are open to trying cultivated meat.
There are many reasons for this gradual shift. The woman biting into Greggs’ famous vegan sausage roll and the woman who carefully crafts her bean burger may have different reasons for choosing meat alternatives. For some, it’s an ethical choice. For others, it’s environmental or health-related. And then there are those of us who are simply curious.
Pea protein powder is used in plant-based meat alternatives.
Either way it’s an industry that, if you’ll excuse the pun, is set to mushroom. According to Boston Consulting Group and Blue Horizon research, the global meat-free sector will be worth US$290 billion by 2035. They also claim Europe will reach peak meat consumption by 2025, and Unilever is aiming to sell US$1 billion-worth of plant-based meat and dairy alternatives by 2025-27.
In his entertaining talk, Dr Baines outlined the extrusion processes that turn wheat and pea proteins into large ropes of fibrous material and how soy isolates are spun into textured proteins using looms like those used in the cotton industry. He explained how calcium is used to imitate the chewable texture of chicken and how Impossible Foods is using the root nodules of bean plants to produce the red colour we recognise so readily in meat.
>> For more interesting SCI webinars on battery developments, medicinal chemistry and more, check out our events page.
So, how close are we to products with the appearance, taste and texture of, let’s say, beef? ‘I think that will come from cultured meat to start with,’ he said. ‘Where the protein is produced, it will still need to be flavoured, but the fibres will have formed and the texture is already present in some of those products.
‘It’s a big ask and it’s been asked for a long time. It’s going to be a long time before you put a piece of steak on one plate and a plant-based [product] on another and they will be visually, texturally and taste(-wise] identical.’
And what appetite do people even have for these plant-based facsimiles? ‘There are people who want plant proteins not to look like meat, and there are people who want them to look like meat,’ he added. ‘The driver at the moment is to make them look like meat, and the driver is to make it taste like meat too.’
Baines wondered aloud about the bizarre fixation some have with recreating and eating foods that look and taste like beef burgers. In contrast, he pointed to the examples of tofu and soy-based products that have been developed in South East Asia – distinct foods that do not serve as meat substitutes.
Plant-based proteins are undoubtedly part of our culinary future, but these products have other barriers to surmount beyond taste and texture. There is no getting around the fact that plant-based proteins are ultra-processed in a time when many are side-stepping processed foods. Baines also explained that these protein- and fibre-rich foods tend to have lower calorific content, but lack vitamins and micronutrients. ‘Will they be supplemented?’ Baines asked. ‘How much will the manufacturers of these new products start to improve the nutritional delivery of these products?’
We have now entered the age of the gluten-free, vegan sausage roll.
But it’s easy to forget that the leaps made in recent years have been extraordinary. Who would have predicted back in 1997 – when Linda McCartney was at the vanguard of the niche, plant-based meat alternative – that a vegan sausage roll would capture the imaginations of a meat-hungry nation? Who would have foreseen fast-food manufacturers falling over each other to launch plant-based burgers and invest in lab-grown meat?
As Dr Baines said: “This is a movement that is not going away.”
>> Our soils provide 97% of our food. Read more about how they are undervalued and overused here.
We always hear about athletes eking out that competitive edge through subtle changes in diet or equipment. Well, when it comes to making our buildings more energy-efficient, dozens of different technologies could make a difference. Every one may not be earth juddering on its own, but each could help decarbonise our homes by degrees.
Phase-changing materials (PCMs) may have a role to play in reducing our reliance on power-hungry cooling and heating systems in the home. At Texas A&M University, researchers have developed PCMs to passively regulate temperatures inside buildings.
They believe their 3D-printed phase-change materials - compounds that can change from a solid to liquid when absorbing heat, or from liquid to solid when releasing heat - could be incorporated into our homes in paint or other interior effects to regulate interior temperatures.
New phase-change material composites can regulate ambient temperatures inside buildings | Image credit: Texas A&M University College of Engineering
Their partial substitute to the heating, ventilation and air conditioning (HVAC) systems that predominate in many of our buildings is a light-sensitive liquid resin with a phase-changing paraffin wax powder.
According to the researchers, their 3D printable ink composite improves upon existing PCMs in that it doesn’t require a separate shell around each PCM particle. When the PCM is mixed with liquid resin, the resin acts as both the shell and building material, enabling thermal energy management without any leakage. They use an ultraviolet light to solidify their 3D printable paste and make it suitable for use in our buildings.
“The ability to integrate phase-change materials into building materials using a scalable method opens opportunities to produce more passive temperature regulation in both new builds and already existing structures,” said Dr. Emily Pentzer, associate professor in the Department of Materials Science and Engineering and the Department of Chemistry.
To date, the researchers have only tested their materials on a small scale in a house-shaped model. Nevertheless, after placing their 3D printed model inside an oven, the results were encouraging. The model’s temperature was 40% different to outside temperatures compared to models made using traditional materials.
From solar panels and insulation to heat pumps and phase change materials, much has been done to make our homes more energy-efficient
“We’re excited about the potential of our material to keep buildings comfortable while reducing energy consumption,” said Dr. Peiran Wei, research scientist in the Department of Materials Science and Engineering and the Soft Matter Facility. “We can combine multiple PCMs with different melting temperatures and precisely distribute them into various areas of a single printed object to function throughout all four seasons and across the globe.”
Perhaps we won’t see PCMs in widespread use in our buildings any time soon, but it’s always heartening to see the use of passive heating and cooling systems in our buildings. Anything that contributes to the decarbonisation mix is certainly worth investigating further.
Think of Earth as an apple and the soil as the peel. Now, imagine that more than 70% of this apple’s surface is covered in water. That veneer of peel suddenly seems very small indeed.
Dig beneath the surface and you realise that the world’s soil resources aren’t as plentiful as you first thought. When you take into account all of the uninhabitable, non-arable land on our planet, including the snow-bound poles and deserts, you’re left with just 3% of total landmass to grow all the fruit and vegetables we eat.
After reminding her listeners of some stark facts at the Soil resources in the UK: overlooked and undervalued? webinar, Jane Rickson, Professor of Soil Erosion and Conservation at Cranfield University, reminded us that soil is a precious, finite resource. “We’re dealing with a very thin resource that has to deliver all of these goods and services.”
You just need to think of your breakfast, lunch, and dinner to realise just how important soil is. Of all the food we eat, 97% comes from terrestrial sources. However, in recent decades, the many benefits brought by soil have been taken lightly. Apart from providing food, animal fodder, and a surface for football, it plays a vital role in climate change mitigation.
‘Soil is excellent for climate change mitigation,’ said Professor Rickson, recipient of the prestigious Dr Sydney Andrew Medal for 2021. ‘We know that healthy soils can support vegetation and crops and plants in taking out atmospheric CO2.’
A cross section of soil layers. Unless you live on fish and seaweed, it’s likely that almost all of your food sources will come from terrestrial sources.
However, she and her colleagues at Cranfield University have unearthed some unsettling facts about the state of our soils. She mentioned that 12 million hectares of agricultural land worldwide is lost each year due to soil degradation. In the UK, soil erosion rates can be as high as 15 tonnes per hectare per year, with soil formation rates only compiling at a rate of 1 tonne per hectare per year; and, based on current rates of erosion, some soils could disappear completely by 2050.
So, what is being done to arrest this problem? The obvious mammoth in the room is climate change, with extreme weather events such as flash floods precipitating a huge amount of soil erosion. Obviously, climate change mitigation measures on a national scale would help, but adjustments to farming practices could also improve soil resilience on a more local level.
A lot of work is also being done to reduce the intensity of farming to improve soil health. The aim, according to Rickson, is to maintain a fertile seedbed while retaining maximum resistance to soil degradation. There are lots of different ways to do this.
One approach being taken is cover cropping, whereby a crop is grown for the protection and enrichment of the soil rather than for immediate sale. This enriches the soil and helps prevent soil erosion. Another approach is strip-tillage – a minimum tillage system that disturbs only the portion of the soil that contains the seed row, with the soil between rows left untilled. She also mentioned the benefits of soil improvement, with poultry manure and mushroom compost used to improve soil health by Benedict Unagwu among others.
Cover crops such as vetch and oats improve the structure and fertility of the soil.
It is difficult not to have sympathy for farmers at the moment. Climate change falls heavily upon their lands, and they must battle flooding and drought to keep their farms financially viable. Professor Rickson often speaks to the farming community about soil health, with the focus placed on realistic solutions. As one farmer told her: ‘It's hard to be green when you’re in the red.’
Perhaps soil doesn’t capture the imagination the same way as an oak forest or a field ablaze with wildflowers, but its mismanagement is costing us a fortune. She estimated that the combined annual economic cost of soil degradation in England, Scotland, and Wales is £1.5 billion.
According to Professor Rickson, the US is probably the home of soil conservation following the harsh ecological lessons learnt from the Dust Bowl disaster of the 1930s. However, she believes the UK has plenty of knowhow in the area.
‘The UK has an opportunity to be world-leading in this,’ she said. ‘I think we are as good as anyone. Our scientific community understands soil and is really pushing the boundaries in terms of soil science.’
From genome mining and green synthesis, to tackling tuberculosis and computational methods to help cure malaria, the chemists of tomorrow have been busy showcasing their talents as part of the Society of Chemical Industry Young Chemists Panel’s National Undergraduate Online Poster Competition 2021.
A snapshot of these students’ talents is bottled below in their own words. So, which one of these 15 entries do you think contains the most potential?
Emmanuelle Acs et al., University of Glasgow
Natural products have always had a privileged place in drug development programmes, but their discovery is long and tedious. Genome mining arises as a solution allowing the finding of compounds never seen before. Using an array of bioinformatic softwares, the myxobacterial genome was explored for new Ribosomally and Post-Translationally modified Peptides (RIPPs). Myxobacteria are soil-dwelling bacteria known for the number of secondary metabolites they produce, and they have proven to hide many more within their genome. Indeed, our analyses have led to the potential discovery of nine new myxobacterial natural products. The nature and class of these products is to be confirmed by biosynthesis in the laboratory.
Olivia Baldwin et al., University of Birmingham
Lanthanides were thought to be biologically irrelevant until the discovery of bacteria containing the lanthanide-dependent methanol dehydrogenase (Ln-MDH) enzyme. There has been interest in exploiting the attractive properties of the lanthanides by the de novo design of artificial proteins, aiming to explore protein structures and functions not observed in biology. Here, a lanthanide-binding peptide, CS1-0, has been designed de novo and shown to bind to europium and pyrroloquinoline-quinone (PQQ), a key component of the Ln-MDH active site. This partial recreation of a biologically relevant lanthanide binding site is a step towards the ultimate goal of de novo design, to create functional artificial metalloproteins with simplified structures.
Janko Hergenhahn et al., University of Oxford
Template-directed synthesis provides a route to achieve porphyrin nanorings by favouring ring-closure reaction over oligomerisation. A structurally new template with 12 binding sites has been proposed for the synthesis of novel porphyrin rings; however, initial unsuccessful reactions have raised questions about the binding efficiency of this template to the linear substrate. We have employed classical and quantum modelling together with experimental techniques to explore template-substrate binding in solution and shed light on this process. Titration experiments and modelling have enabled us to study the occupancy of different binding sites and quantify the influence of strain on binding, further guiding novel designs.
Kieran Benn et al., University of Edinburgh
Hydrocyanation offers an orthogonal route to synthetically ubiquitous amines. Current hydrocyanation methodologies are dominated by the use of acutely toxic hydrogen cyanide gas and transition metal catalysts. Here the application of main-group catalysis and transborylation is reported for the formal hydrocyanation of functionalised alkenes. The catalytic protocol was optimised and applied to a broad range of substrates (20 examples), including examples where chemoselectivity was demonstrated in the presence of reducible functionalities and Lewis basic groups. Mechanistic studies support a proposed catalytic cycle in which B–N/B–H transborylation was a key to catalyst turnover.
Students at the University of Glasgow have used computational analysis to help tackle malaria.
Xiyue Leng et al., University of Birmingham
Antimicrobial peptides are increasingly employed as new-generation antibiotics, with their amphiphilic nature (contain both hydrophobic and cationic components) mimicked by polymers to enable a more cost-effective approach. However, there is a lack of a quantitative pre-experiment indicator to provide a prospect on their potency. The overall hydrophobicity represented by LogP/SA was proposed to rapidly identify candidates in future designing to reduce synthetic efforts. We show a comparison study between two computational tools used to calculate LogP/SA: ChemBio3D and Materials Studio, in terms of the predictive power and sensitivity, followed by the synthesis of copolymers with a different cationic side chain based on the calculation results.
Mirjam-Kim Rääbis et al., University of Glasgow
Traditional small molecule therapeutics in medicinal chemistry often require high doses to inhibit the target protein, leading to issues with safety and drug resistance. Proteolysis targeting chimeras (PROTACs) are a new class of molecule that combat these issues, as they can use the body’s own protein degradation systems to degrade targets even at low drug doses. Virus-targeting chimeras (VIRTACs) can use a similar mechanism to target viral proteins. This project uses molecular docking studies to explore potential VIRTAC warheads that target the papain-like protease of SARS-CoV-2, in an attempt to find a potential treatment to COVID-19 that would, among other benefits, offer a lower risk of antiviral resistance.
Miriam Turner et al., Newcastle University
Tuberculosis remains one of the top 10 causes of death worldwide, therefore there exists an unmet clinical need for new and improved therapeutics that tackle increasing bacterial resistance and affordability issues. Previous studies indicate N-substituted amino acid hydrazides exhibit good activity against several strains of Mtb. Ongoing structure-activity relationship studies utilising isoniazid, a variety of amino acids, and the active imidazo[1,2-a]pyridine-3-carboxy moiety of clinical candidate Q203 have also demonstrated excellent activities. Herein we report the results of our continued evaluation of this architecture, using a scaffold hopping approach to explore the potential of this pharmacophore as a new anti-tubercular drug.
Skye Brettell et al., University of Glasgow
Malaria continues to pose a significant challenge to humanity. Resistance to several frontline antimalarials represents a considerable threat, marking the need for new drugs with novel mechanisms of action. Kinase inhibitors represent a potential new class of antimalarials. TCMDC-135051 is a hit compound with activity against malarial kinase PfCLK3 as well as potency in liver, blood and sexual stage parasites. During this project, sequential analysis of the PfCLK3 catalytic domain identified key structural differences between the target and its human orthologs. Molecular docking studies of TCMDC-135051 analogues using GOLD then yielded potential lead compounds with predicted high affinity for the target kinase.
Matteo Albino et al., University of York
The strain-induced contortion of non-planar, chiroptically-active helicenes caused by fjord steric repulsive interactions is well known. Fjord-mediated planarisation, on the other hand, is far less common and has typically only been achieved via inherently strong covalent bond formation. Herein, I present the properties and density functional theory (DFT) analysis of electroactive azahelicenes exhibiting unexpected through-space π-electronic stabilisation in the reduced states as a result of non-covalent fjord bonding effects. Computational modelling of optical spectra and aromatic-induced current densities reveal that lone pair-repulsive nitrogens in the fjord promote favourable ring currents and reversible helicene planarisation.
Sam Andrew Young et al., Northumbria University
The synthesis of metal chelating molecules, specifically hydroxypyridones (HOPOs), have been identified as potential therapeutic agents for treating Parkinson’s Disease (PD) as bidentate ligands at the two oxygen donor atoms. These ligands are selective for ferric iron in the body, which is expected to stop the reduction of this iron accumulated in the brains of PD sufferers, hindering the Haber-Weiss mechanism from taking place in the mitochondria of the cell and preventing the associated degeneration of the cells. The lipophilicity of these HOPOs is vital to the process, allowing the molecule to transverse the blood-brain barrier, the addition of a triphenylphosphonium group on the HOPO is thought to increase therapeutic effect.
At Heriot Watt University, students have investigated the skin irritation potential of nanoclays using an IATA
Adelaide Lunga et al., Loughborough University
The aim of this project is to develop a short synthesis of N-acetylcolchinol using a greener and step-economical pathway. First, aldol condensation of 3-hydroxyacetophenone and 3,4,5-trimethoxybenzaldehye using ethanolic NaOH produced the respective chalcone. The product was reduced electrochemically in DMSO:MeOH (4:1) employing carbon electrodes and NEt4Cl to the saturated benzylic alcohol, which was converted to an acetamide via Ritter reaction using H2SO4 in MeCN. In the final step, the conditions were optimised to enable electrochemical oxidative coupling of the aromatic groups to give the desired N-acetylcolchinol. This novel four-steps reaction sequence avoids use of transition metal catalysts or toxic reagents.
Yi Xiao et al., University of Oxford
Human endosulfatases (SULFs) are enzymes on the cell surface and in the extracellular matrix that hydrolyse 6-O-sulfate on glucosamine units within heparan sulfate proteoglycans. SULFs are involved in growth and development, muscle regeneration and tumour growth via various signaling pathways, with untapped therapeutic and diagnostic potentials. However, profiling SULFs remains a challenge. Antibodies detect their presence, but do not indicate their activity state. The current activity assay is a global sulfatase assay and is not selective in a biological sample. We propose a novel small-molecule probe to profile SULF activity by exploiting the formation of 1,6-anhydrosugar, which can be potentially used in isolated proteins and in vitro.
Alexander Pine et al., University of Greenwich
Solubility parameters are important for pharmaceutical formulations, paint formulations and new material development. There is a need to improve the accuracy of solubility calculations, and to be able to make rapid predictions of the solubility of new molecular structures. In this project, a range of Python plugins, and open-source codes have been used to develop a Lasso linear regression machine learning model to predict the Hansen solubility parameters (HSP) - δd, δp and δh, which represents dispersion forces, dipole-permanent dipole forces and hydrogen bonding respectively with the intention of making faster and more accurate prediction in solubility.
Alexander David Robertson et al., The University of Glasgow
This research considers computational modelling of a SPAAC reaction involving cyclononyne. DFT calculations were performed on the strain promoted reaction between cyclononyne and mesyl azide. Three low energy conformers of cyclononyne with Cs, C2 and C1 symmetry were found with similar energy. The transition structures for the corresponding cycloaddition with mesyl azide were found and the C2 conformer was the lowest in energy. Product structures were found leading to the identification of the thermodynamic product of the reaction. Distortion/interaction analysis showed that the cycloalkyne was already significantly pre-constrained to its reacting geometry.
Holly King et al., Heriot Watt university
Clays are natural nanomaterials consisting of mineral silicate layers. They have several functional uses in everyday life. An example of nanoclays that carry out a wide range of roles is smectites which include montmorillonite (MMT), bentonite and hectorite. These nanoclays can be used in cosmetics, altering their appearance and in pharmaceuticals as drug carriers and wound dressings. Integrated approach to testing and assessment (IATA) aim to collect all relevant data into one easy to understand format that can be used to group materials. Using an IATA dedicated to skin irritation/corrosion it was found that MMT was safe for use. However, hectorite was found to be toxic at high doses indicating that it is a possible irritant to the skin.
Many thanks to the sponsors of this year’s competition: GSK, AstraZeneca, TeledyneIsco. The event runs until 9 July, so let us know what you think of the entries on Twitter at #SCIPosterComp.
If you’d like to see these students’ full posters, go to: https://istry.co.uk/postercompetition/5/?date_example=2021-06-28
Which technologies will propel industry forward and give companies that competitive advantage? According to digital consultancy McKinsey Digital’s Tech Trends Index, several technologies will have a profound and disruptive impact on industries including the chemical sector. So, which ones will have the biggest effect on the way you work in the coming decade?
By 2025, more than 50 billion devices around the world will be connected to the Industrial Internet of Things (IIOT) and about 600,000 industrial robots a year will be in place from 2022. The combination of these, along with industrial processes such as 3D and 4D printing, will speed up processing and improve operational efficiency.
According to McKinsey, 50% of today’s work practices could be automated by 2022 as ever more intelligent robots (in physical and software form) increase production and reduce lead times. So, how does this change look in the real world?
According to the McKinsey Tech Trends Index, 10% of today’s manufacturing processes will be replaced by additive manufacturing by 2030.
According to the Tech Trends Index, one large manufacturer has used collaborative robots mounted on automatic guided vehicles to load pallets without human involvement, while an automotive manufacturer has used IIOT to connect 122 factories and 500 warehouses around the world to optimise manufacturing and logistics, consolidate real-time data, and boost machine learning throughput.
An almost incredible 368,000 patents were granted in next generation computing in 2020. Advanced computing will speed up the processing of reams of data to optimise research and cut development times for those in the chemicals and pharmaceuticals industries, accelerate the use of autonomous vehicles, and reduce the barriers to industry for many eager entrants.
‘Next-generation computing enables further democratisation of AI-driven services, radically fast development cycles, and lower barriers of entry across industries,’ the index notes. ‘It promises to disrupt parts of the value chain and reshape the skills needed (such as automated trading replacing traders and chemical simulations, reducing the need for experiments).’
According to McKinsey, AI will also be applied to molecule-level simulation to reduce the empirical expertise and testing needed. This could disrupt the materials, chemicals, and pharmaceuticals industries and lead to highly personalised products, especially in medicine.
It doesn’t take much investigation before you realise that the bio-revolution has already begun. Targeted drug delivery and smart watches that analyse your sweat are just two ways we’re seeing significant change.
The Tech Trends Index claims the confluence of biological science and the rapid development of AI and automation are giving rise to a revolution that will lead to significant change in agriculture, health, energy and other industries.
In the health industry, it seems we are entering the age of hyper-personalisation. The Index notes that: ‘New markets may emerge, such as genetics-based recommendations for nutrition, even as rapid innovation in DNA sequencing leads ever further into hyper personalised medicine.’ One example of this at work in the agri-food industry is Trace Genomics’ profiling of soil microbiomes to interpret health and disease-risk indicators in farming.
It’s no secret that we will need to develop lighter materials for transport, and others that have a lighter footprint on our planet. According to McKinsey, next generation materials will enhance the performance of products in pharma, energy, transportation, health, and manufacturing.
For example, molybdenum disulfide nanoparticles are being used in flexible electronics, and graphene is driving the development of 2D semiconductors. Computational materials science is another area of extraordinary potential. McKinsey explains: ‘More new materials are on the way as computational-materials science combines computing power and associated machine-learning methods and applies them to materials-related problems and opportunities.’
5G networks will help take autonomous vehicles from tentative - to widespread use.
So, which sorts of advanced materials are we talking about? These include nanomaterials that enable more efficient energy storage, lighter materials for the aerospace industry, and biodegradable nanoparticles as drug carriers within the human body.
These are just four of the 10 areas explored in the fascinating McKinsey Digital’s Tech Trends report. To read more about the rest, visit: https://www.mckinsey.com/business-functions/mckinsey-digital/our-insights/the-top-trends-in-tech
Watching plants grow in a hydroponic contraption is an education. The plants sit in foam under UV light while their roots feed on water fortified by plant feed. There is no soil. No thirst. No room for death by lazy gardener. The results, as any hydroponic enthusiast will tell you, are startling.
So, what if we were to adopt this targeted, optimised approach to our own nutrition? What would happen if he were to ditch that delicious Sunday roast in favour of a shake that contains all the vitamins and minerals your body needs? Admittedly, it sounds terrible, but people do something similar already. Many gym obsessives take protein shakes religiously to feed their bodies’ impressive musculature, while others skip meals entirely in favour of such drinks and supplements.
An organic hydroponic vegetable cultivation farm
A recent study conducted by the Cherab Foundation, which featured in the Alternative Therapies journal, concludes that nutritional supplements may also help boost our brain function. After giving 77 people a vitamin and meal replacement product called IQed Smart Nutrition, the researchers from the non-profit organisation found that the supplement boosted brain function in a range of areas and could help people with autism, apraxia, and ADHD.
Almost 84% of participants reported deficits in speech and communication prior to taking the nutritional supplements. After taking the product, more than 85% said their expressive speech had improved while 67% of respondents reported improvements in other areas including focus, language understanding, oral motor skills, and physical and behavioural health.
Overall, 64% of participants reported positive changes within two weeks. According to the Cherab Foundation, the research aims “to guide future research into the dietary interventions and potential management of neurological conditions using natural food products, vitamin and mineral supplements”.
So, what ingredients are in the supplement-infused chocolate shake that will replace the wood-fired pizza you’re due to have next Friday evening? According to IQed, its powdered chocolate offering contains everything from brown rice, apple fibres, turmeric, and green tea, to copper gluconate, amalaki, cayenne pepper, and chia seeds.
Turmeric, cayenne pepper, and chia seeds have hopped onto the superfood bandwagon in recent years.
Some will dismiss these supplements as hocus-pocus, but the potential benefits of optimised nutrition are exciting nonetheless. If some wince-inducing elixir makes us healthier, stronger and live longer, perhaps it’s worth investigating further?
The Cherub Foundation works to improve the communication skills, education, and advocacy of children on the neurological spectrum. To read more about its study, visit: https://pubmed.ncbi.nlm.nih.gov/32088673/
As silicon reaches its solar ceiling, perovskite has emerged as one of the main materials of choice in the next generation of solar panels. Indeed, Oxford PV’s much anticipated perovskite-silicon solar cell could take conversion efficiency well beyond what is currently achieved on the roofs of our homes.
The benefits of perovskite are well known at this stage. It could increase the energy we harvest from the sun and improve solar cell efficiency, and its printability could make fabrication cheaper. However, as with almost everything, there are drawbacks.
According to researchers at the SPECIFIC Innovation and Knowledge Centre at Swansea University, the solvents used to control the crystallisation of the perovskite during fabrication hinder the large-scale manufacture of printed carbon perovskite cells. This is due to the toxicity and potentially psychoactive effects of these materials.
The SPECIFIC team claims to have found a way around this after discovering a non-toxic biodegradable solvent called γ-Valerolactone. They say this replacement solvent could be used without affecting solar cell performance. Furthermore, they say it is non-toxic, sustainable, and suitable for large-scale manufacturing.
Left - solvent normally used to make solar cells, which is toxic.
Right - new green solvent developed by Swansea University researchers from the SPECIFIC project
| Image Credit: Swansea University
‘This solvent problem was a major barrier, not only restricting large-scale manufacture but holding back research in countries where the solvents are banned,’ said research group leader Professor Trystan Watson. ‘We hope our discovery will enable countries that have previously been unable to participate in this research to become part of the community and accelerate the development of cleaner, greener energy.’
As the conversion efficiency of solar panels improves, cost is also key. What if you could create the same solar panels in a more cost-efficient way? That was part of the thinking behind another recent innovation in Singapore, where Maxeon Solar Technologies has created frameless, lightweight rooftop solar panels. These solar panels can be adhered directly to a roof without racking or mounting systems and allegedly perform just as well as standard solar panels.
The new Maxeon Air technology platform from Maxeon Solar Technologies
‘For close to 50 years, the solar power industry has almost exclusively used glass superstrate panel construction,’ said Jeff Waters, CEO of Maxeon Solar Technologies. ‘As solar panels have increased in size, and the cost of solar cells has been dramatically reduced, the cost of transporting, installing and mounting large glass panels has become a relatively larger portion of total system cost. With Maxeon Air technology, we can now develop products that reduce these costs while opening up completely new market opportunities such as low-load commercial rooftops.’
The idea is to use these peel-and-stick designs on low-load roofs that cannot support the weight of conventional solar systems; and they will be rolled out in 2022. Time will tell whether the innovations in Swansea and Singapore have a bearing on companies’ solar systems, but they provide more evidence of the ingenuity that is making solar power cheaper and more efficient.
We’re starting to see those silent cars everywhere. The electric vehicle evolution is gradually seeping onto our roads. Every month or two, we also seem to read about another wind power generation record in the UK, or some super solar cell. Pension funds and big corporations are coming under great pressure to divest from fossil fuels. The clean power revolution is well underway.
And yet the third biggest polluter of the planet - after power and transport - awaits the seismic shift that will shake it to its foundations. Indeed, cement production still accounts for roughly 8% of the world’s greenhouse gas emissions.
The problem is that creating cement is an energy-intense, polluting process with firing temperatures of 2,700 degrees Fahrenheit needed to create it, and plenty of CO2 released during processing.
Green cement and concrete are needed to reduce emissions in construction and other industries.
But there are signs that the processing could become cleaner. A recent report released by Market Research Future (MRFR) predicts that concrete (of which cement is a key ingredient) use could get appreciably greener over the next six years. It estimates that the global green concrete market size will grow at a 9.45% compound annual growth rate from 2020-27.
MRFR attributes this rise to several factors. First, there is a growing demand for green or recycled concrete (that incorporates waste components) within the construction industry. For builders, it enhances their environmental credentials and will increasingly become a business-savvy investment as governments seek to reduce carbon emissions.
Green building codes and the creation of energy-efficient infrastructure will also help propel this growth, and changing building regulations in massive markets including China, India, and the Middle East will result in many manufacturers looking to develop different material combinations. Increasingly, we’re seeing manufacturers turning to less energy-intensive manufacturing methods and investigating which waste materials could be used to create a greener cement or concrete that doesn’t compromise on performance.
Researchers at Chalmers University of Technology, in Sweden, have even been developing a rechargeable cement-based battery. If it ever comes to pass, this could be used to create buildings that store energy like giant batteries. Some manufacturers are also looking into the electrification of kilns, which isn’t feasible yet, and carbon capture and storage has long been mooted as a means to reduce industrial emissions.
Imagine an entire twenty storey concrete building that can store energy like a giant battery. This could be possible if Chalmers University’s cement-based rechargeable batteries come to fruition. | Image Credit: Yen Strandqvist/Chalmers University of Technology
The good news is that we don’t just have people all over the world working on low-carbon materials and manufacturing methods; experts in the UK are tackling the issue right now. On 2 June, speakers at the SCI’s free webinar, Ultra-low carbon concrete, a sustainable future, will examine some of the exciting initiatives underway.
These include an award winning, industry accepted ultra-low carbon alternative to traditional cement, which could result in CO2 savings of up to 78%, and the potential of using offsite manufacturing to provide commercial projects with a sustainable structural frame solution.
As with transport and power, cement is getting greener increment by increment. But with drastic climate change consequences dangling above us like the Sword of Damocles, now is the time for concrete action.
Register for Ultra-low carbon concrete, a sustainable future today at: https://bit.ly/33WfjkN.
Sometimes, when you try to solve one problem, you create another. A famous example is the introduction of the cane toad into Australia from Hawaii in 1935. The toads were introduced as a means of eliminating a beetle species that ravaged sugar cane crops; but now, almost a century later, Western Australia is inundated with these venomous, eco-system-meddling creatures.
In a similar spirit, disposable face masks could help tackle one urgent problem while creating another. According to researchers at Swansea University, nanoplastics and other potentially harmful pollutants have been found in many disposable face masks, including the ones some use to ward off Covid-19.
After submerging various types of common disposable face masks in water, the scientists observed the release of high levels of pollutants including lead, antimony, copper, and plastic fibres. Worryingly, they found significant levels of pollutants from all the masks tested.
Microscope image of microfibres released from children's mask: the colourful fibres are from the cartoon patterns | Credit: Swansea University
Obviously, millions have been wearing single-use masks around the world to protect against the Covid-19 pandemic, but the release of potentially harmful substances into the natural environment and water supply could have far-reaching consequences for all of us.
‘The production of disposable plastic face masks (DPFs) in China alone has reached approximately 200 million a day in a global effort to tackle the spread of the new SARS-CoV-2 virus,’ says project lead Dr Sarper Sarp, whose team’s work has been published on Science Direct. ‘However, improper and unregulated disposal of these DPFs is a plastic pollution problem we are already facing and will only continue to intensify.
The presence of potentially toxic pollutants in some face masks could pose health and environmental risks.
‘There is a concerning amount of evidence that suggests that DPFs waste can potentially have a substantial environmental impact by releasing pollutants simply by exposing them to water. Many of the toxic pollutants found in our research have bio-accumulative properties when released into the environment and our findings show that DPFs could be one of the main sources of these environmental contaminants during and after the Covid-19 pandemic.’
The Swansea scientists say stricter regulations must be enforced during manufacturing and disposal of single-use masks, and more work must be done to understand the effect of particle leaching on public health and on the environment. Another area they believe warrants investigation is the amount of particles inhaled by those wearing these masks.
‘This is a significant concern,’ adds Sarp, ‘especially for health care professionals, key workers, and children who are required to wear masks for large proportions of the working or school day.’
Every tin can dropped into our recycling bins is a small act of faith. We hope each one is recycled, yet the figures take some of that fervour from our faith. According to UK government statistics from 2015-2018, only about 45% of our household waste is recycled. Similarly, the UN has noted that only 20% of the 50 million tonnes of electronics waste produced globally each year is formally recycled. So, it’s fair to say we could do better.
Thankfully, thousands of people around the globe are working on these problems and two recent developments give us grounds for optimism. The first involves upcycling metal waste into multi-purpose aerogels, and the second involves fully recyclable printed electronics that include a wood-derived ink.
Researchers at the National University of Singapore (NUS) claim to have turned one person’s trash into treasure with a low-energy way to convert aluminium and magnesium waste into high value aerogels for the construction industry.
To do this, they ground the metal waste into a powder and mixed it with chemical cross-linkers. They heated this mixture in an oven before freeze-drying it and turning it into an aerogel. The team says this simple process makes their aerogels 50% cheaper than commercially available silica aerogels.
Aerogels have many useful properties. They are absorbent, extremely light (hence the frozen smoke nickname), and have impressive thermal and sound insulation capabilities. This makes them useful as thermal insulation materials in buildings, in piping systems, or for cleaning up oil spills. However, the NUS team has loftier goals than that.
There is a great need for less energy intensive ways to recycle metals
“Our aluminium aerogel is 30 times lighter and insulates heat 21 times better than conventional concrete,” research team leader Associate Professor Duong Hai-Minh whose research has been published in the Journal of Material Cycles and Waste Management. “When optical fibres are added during the mixing stage, we can create translucent aluminium aerogels which, as building materials, can improve natural lighting, reduce energy consumption for lighting and illuminate dark or windowless areas. Translucent concrete can also be used to construct sidewalks and speed bumps that light up at night to improve safety for pedestrians and road traffic.”
The aerogels could even be used for cell cultivation. Professor Duong explains: “Microcarriers are micro-size beads for cells to anchor and grow. Our first trials were performed on stem cells, using a cell line commonly used for testing of drugs as well as cosmetics, and the results are very encouraging.”
Whatever about these speculative applications, this upcycling method will hopefully help us find new homes for all types of metal waste including metal chips and discarded electronics.
A team at Duke University has also made interesting progress in reducing electronic waste. The researchers claim to have developed fully recyclable printed electronics that could be used and reused in a wide range of sensors.
The researchers’ transistor is made from three carbon-based inks that can be printed onto paper, and their use of a wood-derived insulating dielectric ink called nanocellulose helps make them recyclable. Carbon nanotubes and graphene inks are also used for the semiconductors and conductors, respectively.
A 3D rendering of the first fully recyclable, printed transistor. CREDIT: Duke University
“Nanocellulose is biodegradable and has been used in applications like packaging for years,” said Aaron Franklin, the Addy Professor of Electrical and Computer Engineering at Duke, whose research has been published in Nature Electronics. “And while people have long known about its potential applications as an insulator in electronics, nobody has figured out how to use it in a printable ink before. That’s one of the keys to making these fully recyclable devices functional.”
The team has developed a way to suspend these nanocellulose crystals (extracted from wood fibres) with a sprinkling of table salt to create an ink that performs well in its printed transistors. At the end of their working life, these devices can be submerged in baths with gently vibrating sound waves to recover the carbon nanotubes and graphene components. These materials can be reused and the nanocellulose can be recycled just like ordinary paper.
The team conceded that these devices won’t ruffle the trillion dollar silicon-based computer component market, but they do think these devices could be useful in simple environmental sensors to monitor building energy use or in biosensing patches to track medical conditions.
Read about the Duke University research here: https://www.nature.com/articles/s41928-021-00574-0
Take a look at the NUS study here: https://link.springer.com/article/10.1007/s10163-020-01169-1
To some, the almond is a villain. This admittedly tasty nut takes an extraordinary amount of water to grow (1.1 gallons per nut) and some in California say almond cultivation has contributed to drought.
And so it is no surprise to see the almond lined up in the rogue’s gallery of the thirstiest foods. In a study in the journal Nature Food, University of Michigan (U-M) and Tulane University researchers assessed how the food we eat affects water scarcity.
Meat consumption was found to be the biggest culprit in the US, with the hooves and feet of livestock accounting for 31% of the water scarcity footprint. Within the meat category, beef is the thirstiest, with almost six times more water consumption than chicken.
Almond crops in California have come under heavy criticism due to their heavy water consumption
However, the picture is a little more nuanced. Lead author Martin Heller, of U-M's School for Environment and Sustainability, explains: “Beef is the largest dietary contributor to the water scarcity footprint, as it is for the carbon footprint. But the dominance of animal-based food is diminished somewhat in the water scarcity footprint, in part because the production of feed grains for animals is distributed throughout less water-scarce regions, whereas the production of vegetables, fruits and nuts is concentrated in water-scarce regions of the United States, namely the West Coast states and the arid Southwest.”
Certain types of diets drain the water supply. People who eat large quantities of beef, nuts such as the infamous almond, walnut, and cashew, and a high proportion of water-intense fruits and vegetables including lemon, avocado, asparagus, broccoli, and cauliflower take a heavy toll on the water footprint.
The Brussels sprout is not just for Christmas… it is a less water intense option for your dinner table.
“The water-use impacts of food production should be a key consideration of sustainable diets,” adds study co-author Diego Rose of Tulane University. “There is a lot of variation in the way people eat, so having a picture with this sort of granularity – at the individual level – enables a more nuanced understanding of potential policies and educational campaigns to promote sustainable diets.”
So, what do you do the next time you feel a pang of water guilt? According to the researchers, you could swear off asparagus and that crushed avocado on your toast and replace them with less water intense foods such as fresh peas, Brussels sprouts, cabbage, and kale (but maybe not on your toast). Those beef steaks and hamburgers could make way for other protein sources, such as chicken, pork, and soybeans, and you could graze on peanuts and seeds instead of those honey roasted almonds you love so dearly. Just think of all those gallons of water you’ll save.
For more on this study, visit: https://www.nature.com/articles/s43016-021-00256-2
Bit by bit, the green hydrogen revolution is coming to our shores. The news that a planning application has been filed for the UK’s largest electrolyser in Glasgow could be a boon for hydrogen evangelists, the local communities, and the political class.
The 20MW electrolyser will form part of the green hydrogen facility on the outskirts of Glasgow near Whitelee, the UK’s largest wind farm. The proposed project would produce up to 8 tonnes of green hydrogen each day – the equivalent of 550 return bus trips from Glasgow to Edinburgh.
If approved, the scheme would be delivered by ScottishPower, BOC, and ITM Power as part of the Green Hydrogen for Scotland Partnership. BOC would operate the facility using solar and wind power produced by Scottish Power and ITM Power would provide the all-important 20 MW electrolyser. Renewable energy would power the electrolyser, which would split the water into hydrogen and oxygen gas. The hydrogen produced by this process could then be used in various applications including transport.
Fundamentally, the people who will benefit most are the people of Glasgow, with the project aiming to provide carbon-free transport and clean air for people across the city area, while satisfying some industrial hydrogen demand. And we can all rest easy now that we know politicians will be pleased about it too, for the project coincides nicely with the United Nations 26th Climate Change Conference, which will be held in Glasgow later this year.
The new facility will be based beside a plentiful renewable energy source, Whiteless wind farm in Eaglesham Moor. | Editorial credit: Maritxu / Shutterstock.com
If all goes swimmingly, the facility will supply hydrogen for the commercial market by 2023. “Whitelee keeps breaking barriers, first the UK’s largest onshore wind farm, and soon to be home to the UK’s largest electrolyser,” says Barry Carruthers, ScottishPower’s Hydrogen Director. “The site has played a vital role in helping the UK to decarbonise and we look forward to delivering another vital form of zero carbon energy generation at the site to help Glasgow and Scotland achieve their net zero goals.”
Tumbling renewable prices
This exciting news follows on the back of some bold green hydrogen claims made in a recent Bloomberg New Energy Foundation (NEF) report: the 1H 2021 Hydrogen Levelised Cost Update. According to Martin Tengler, BloombergNEF’s Lead Hydrogen Analyst, the report authors believe the cost of renewable hydrogen could fall 85% by 2050, 17% lower than they had previously predicted. This, he says, is due to falling renewables prices.
It is becoming cheaper all the time to produce solar and wind power, which is good news for those producing green hydrogen.
Tengler also says that renewable hydrogen should be cheaper than blue hydrogen (when natural gas is split into hydrogen and CO2 via processes such as steam methane reforming) in many countries by 2030. Furthermore, Bloomberg NEF predicts that green hydrogen will be cheaper to process than natural gas in many countries by 2050.
With the prices of solar and wind power constantly tumbling, it would be no surprise to see the authors of these reports revising their projections even further in the coming years. In the mean-time, we welcome the green shoots peeking through outside Glasgow.
Many of us have contemplated buying a reconditioned phone. It might be that bit older but it has a new screen and works as well as those in the shop-front. I’m not sure, however, that any of us have thought of investing in a reconditioned liver – but it could be coming to a body near you.
Researchers based in São Paulo’s Institute of Biosciences have been developing a technique to create and repair transplantable livers. The proof-of-concept study published in Materials Science and Engineering by the Human Genome and Stem Cell Research Centre (HUG-CELL) is based on tissue bioengineering techniques known as decellularisation and recellularisation.
The organs of some donors are sometimes damaged in traffic accidents, but these may soon be transplantable if the HUG-CELL team realises its goal.
The decellularisation and recellularisation approach involves taking an organ from a deceased donor and treating it with detergents and enzymes to remove all the cells from the tissue. What remains is the organ’s extracellular matrix, containing its original structure and shape.
This extracellular matrix is then seeded with cells from the transplant patient. The theoretical advantage of this method is that the body’s immune system won’t rile against the new organ as it already contains cells from the patient’s own body, thereby boosting the chance of long-term acceptance.
However, the problem with the decellularisation process is that it removes the very molecules that tell cells to form new blood vessels. This weakens cell adhesion to the extracellular matrix. To get around this, the researchers have introduced a stage between decellularisation and recellularisation. After decellularising rat livers, the scientists injected a solution that was rich in the proteins produced by lab-grown liver cells back into the extracellular matrix. These proteins then told the liver cells to multiply and form blood vessels.
These cells then grew for five weeks in an incubator that mimicked the conditions inside the human body. According to the researchers, the results showed significantly improved recellularisation.
“It’s comparable to transplanting a ‘reconditioned’ liver, said Mayana Zatz, HUG-CELL’s principal investigator and co-author of the article. “It won't be rejected because it uses the patient’s own cells, and there’s no need to administer immunosuppressants.”
Extracellular matrix of a decellularised liver | Image Credit: HUG-CELL/USP
Obviously, there is a yawning gap between proof of concept and the operating theatre, but the goal is to scale up the process to create human-sized livers, lungs, hearts, and skin for transplant patients.
“The plan is to produce human livers in the laboratory to scale,” said lead author Luiz Carlos de Caires-Júnior to Agência FAPESP. “This will avoid having to wait a long time for a compatible donor and reduce the risk of rejection of the transplanted organ."
This technique could also be used to repair livers given by organ donors that are considered borderline or non-transplantable. “Many organs available for transplantation can’t actually be used because the donor has died in a traffic accident,” Caires-Júnior added. “The technique can be used to repair them, depending on their status.”
Even if we are at the early stages of this approach, it bodes well for future research. And for those on the organ transplant list, a reconditioned liver would be as good as a new one – complete with their very own factory settings.
Read the paper here: https://www.sciencedirect.com/science/article/abs/pii/S0928493120337814
When you live in a cold country, you think of hot days as a blessing. Air conditioning units are for those in far-away places – humid countries where the baked earth smell rises to meet you when you step off the plane.
But cooling comes at a cost. According to the UN Environment Programme, it accounts for 7% of global greenhouse gas emissions. Some of us are visual learners; so, the sheer cost of cooling really hit me when I stared up at an apartment building in Hong Kong with hundreds of air conditioning units perched above the windows like birds.
And it isn’t just the Hong Kongers feeling the heat. The cooling industry as a whole is under pressure to cut its greenhouse gas emissions. The International Energy Agency expects emissions from cooling to double by 2030 due to heat waves, population growth, urbanisation, and the growing middle class. By 2050, it forecasts that space cooling will consume as much electricity as China and India do today.
Air conditioning units cling to a building
All of this was captured by the Cooling Suppliers: Who's Winning the Race to Net Zero report released by the Race to Zero campaign, the Kigali Cooling Efficiency Program (K-CEP), Carbon Trust and other partners in the UN Environment Programme-hosted Cool Coalition.
This report's authors found that only five of the 54 cooling companies they assessed have committed to net-zero targets. The document outlines three areas that must be addressed on the Cooling Climate Pathway: super-efficient appliances, ultra-low global warming refrigerants, and the widespread adoption of passive cooling measures such as clever home design and urban planning.
So, while builders adjust window sizes, introduce trees for shading, and choose materials (such as terracotta cooling systems) thoughtfully to temper the sun’s gaze, others are availing of different methods.
For example, the COP26 (the 2021 UN Climate Change Conference) Champions Team has just released its Net Zero Cooling Action Plan that includes a Cool Calculator tool to help companies and governments run simple calculations to see where they could decarbonise their cooling systems. Similarly, the UK's Environmental Investigation Agency (EIA) has launched a net-zero cooling product guide that showcases energy-efficient products run on natural refrigerants.
Green walls are one of many passive cooling approaches used to reduce our reliance on mechanical systems.
However, it’s clear that the softly-softly approach won’t suffice. The EIA has called on governments to do more to encourage organisations to adopt sustainable cooling, to make concrete policy commitments, and speed-up the phase-out of climate-warming refrigerants such as hydrofluorocarbons.
“The development and expansion of net-zero cooling is a critical part of our Race to Zero emissions,” said Nigel Topping, UK High Level Champion for COP26. “In addition to technological breakthroughs and ambitious legislation, we also need sustainable consumer purchasing to help deliver wholesale systems change.”
We all love the technological panacea – innovations that will cure all the climate ills we have inflicted on the world. But the solution will also involve stodgy government regulations and changing consumer habits, and a reliance on the continued fall in renewable power generation.
For those in traditionally cooler climes, it’s no longer someone else’s problem. It was a balmy 22°C in London this week and we’re not even in April yet. So, it’s certainly time to turn up the heat on the cooling industry.
Every day, there are subtle signs that machine learning is making our lives easier. It could be as simple as a Netflix series recommendation or your phone camera automatically adjusting to the light – or it could be something even more profound. In the case of two recent machine-learning developments, these advances could make a tangible difference to both microscopy, cancer treatment, and our health.
The first is an artificial intelligence (AI) tool that improves the information gleaned from microscopic images. Researchers at the University of Gothenburg have used this deep machine learning to enhance the accuracy and speed of analysis.
The tool uses deep learning to extract as much information as possible from data-packed images. The neural networks retrieve exactly what a scientist wants by looking through a huge trove of images (known as training data). These networks can process tens of thousands of images an hour whereas some manual methods deliver about a hundred a month.
Machine learning can be used to follow infections in a cell.
In practice, this algorithm makes it easier for researchers to count and classify cells and focus on specific material characteristics. For example, it can be used by companies to reduce emissions by showing workers in real time whether unwanted particles have been filtered out.
“This makes it possible to quickly extract more details from microscope images without needing to create a complicated analysis with traditional methods,” says Benjamin Midtvedt, a doctoral student in physics and the main author of the study. “In addition, the results are reproducible, and customised. Specific information can be retrieved for a specific purpose."
The University of Gothenburg tool could also be used in health care applications. The researchers believe it could be used to follow infections in a cell and map cellular defense mechanisms to aid the development of new medicines and treatments.
Machine learning by colour
On a similar thread, machine learning has been used to detect cancer by researchers from the National University of Singapore. The researchers have used a special dye to colour cells by pH and a machine learning algorithm to detect the changes in colour caused by cancer.
The researchers explain in their APL Bioengineering study that the pH (acidity level) of a cancerous cell is not the same as that of a healthy cell. So, you can tell if a cell is cancerous if you know its pH.
With this in mind, the researchers have treated cells with a pH-sensitive dye called bromothymol blue that changes colour depending on how acidic the solution is. Once dyed, each cell exudes its unique red, green, and blue fingerprint.
By isolating a cell’s pH, researchers can detect the presence of cancer.
The authors have also trained a machine learning algorithm to map combinations of colours to assess the state of cells and detect any worrying shifts. Once a sample of the cells is taken, medical professionals can use this non-invasive method to get a clearer picture of what is going on inside the body. And all they need to do all of this is an inverted microscope and a colour camera.
“Our method allowed us to classify single cells of various human tissues, both normal and cancerous, by focusing solely on the inherent acidity levels that each cell type tends to exhibit, and using simple and inexpensive equipment,” said Chwee Teck Lim, one of the study’s authors.
“One potential application of this technique would be in liquid biopsy, where tumour cells that escaped from the primary tumour can be isolated in a minimally invasive fashion from bodily fluids.”
The encouraging sign for all of us is that these two technologies are but two dots on a broad canvas, and machine learning will enhance analysis. There are certainly troubling elements to machine learning but anything that helps hinder disease is to be welcomed.
Machine Learning-Based Approach to pH Imaging and Classification of Single Cancer Cells:
Quantitative Digital Microscopy with Deep Learning:
What do grape stalks, pineapple leaves, corn cobs, rice husks, sheep’s wool, and straw have in common? Apart from being natural materials, they have all been used to insulate homes. Increasingly, people are turning towards natural, sustainable materials as climate change and waste have become bigger problems.
Existing building insulation materials such as synthetic rock wool are excellent at keeping our homes warm in winter, but the conversation has moved beyond thermal performance. Energy use, re-usability, toxicity, and material disposal are all live considerations now, especially with regulations and emissions targets tightening. So, rock wool might perform better than straw bale insulation but straw is biodegradable, reusable, easy to disassemble, and doesn’t require large amounts of energy to process.
Sheep’s wool and hemp insulation have also become attractive to homeowners and housebuilders alike, but an even more encouraging prospect is the use of waste materials to create next generation insulation. In this spirit, researchers at Flinders University in Adelaide, Australia, have taken waste cooking oil, wool offcuts, and sulphur to process a novel housing insulation material.
Recycled paper is one of many waste materials that has found its way into domestic insulation.
To make this composite, they followed several stages. In the first stage of the synthesis, the researchers used inverse vulcanisation to create a polysulphide polymer from canola oil triglyceride and sulphur. They then mixed this powdered polymer with wool and coated the fibres through electrostatic attraction. This mixture was compressed through mild heating to provoke S−S metathesis in the polymer and bind the wool. The wool bolsters the tensile strength of the material, makes it less flammable, and provides excellent insulation. The result is a sustainable building material that fulfils its function without damaging the environment.
For Associate Professor Justin Chalker, the lead author of this study, this work provides an ideal jumping-off point. “The promising mechanical and insulation properties of this composite bodes well for further exploration in energy saving insulation in our built environment,” he said.
It is clear that ventures like the one in Adelaide will continue to sprout all over the world. After all, necessity dictates that we change the way we build our homes and treat materials.
A recent report from Emergen Research predicts that the global insulation materials market will be worth US $82.96 billion (£59.78 billion) by 2027. The same report was also at pains to mention that the increasing demand for reduced energy consumption in buildings will be a significant factor in influencing industry growth.
“Market revenue growth is high and expected to incline rapidly going ahead due to rising demand for insulation materials... to reduce energy consumption in buildings,” it said. One of the main reasons given for this increased green building demand was stricter environmental regulations.
And Emergen isn’t the only organisation feeling the ground moving. Online roofing merchant Roofing Megastore, which sells more than 30,000 roofing materials, has detected a shift towards environmentally friendly materials, with many homeowners sourcing these products themselves.
Rock wool insulation panels have come under greater scrutiny in recent times.
Having analysed two years of Google search data on sustainable building materials, the company found that synthetic roof tiles are generating the most interest from the public. Like the Flinders insulation, these roof tiles make use of waste materials, in this case recycled limestone and plastic. And you don’t need to look far down the list to find sustainable insulation materials, with sheep’s wool insulation in 9th place, wood fibre insulation in 10th, and hemp insulation in 12th.
Over time, the logic of the progression towards natural, less energy-intensive building materials will become harder to ignore. “Traditional materials such as synthetic glass mineral wool offer high levels of performance but require large amounts of energy to produce and must be handled with care while wearing PPE,” the company noted. “Natural materials such as hemp or sheep’s wool, however, require very little energy to create and can be installed easily without equipment.”
So, the next time you look down at your nutshells, spent cooking oil, or tattered woollen sweater, think of their potential. In a few years, these materials could be sandwiched between your walls, keeping you warm all winter.
Insulating composites made from sulphur, canola oil, and wool (2021): https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202100187?af=R